Results 61 to 70 of about 3,593 (197)

Mechanochemical Treatment of Cellulose: A Strategy for Developing Functional Biocomposite Materials

Polymer Engineering &Science, Volume 66, Issue 2, Page 662-688, February 2026.
Mechanochemistry as an integrated approach for combining fiber defibrillation, activation, surface functionalization, and cellulose‐based composite fabrication in a single or reduced number of steps. ABSTRACT Cellulose‐based biocomposites are attracting increasing scientific and industrial interest due to their sustainable origin, biodegradability, and
Murilo O. da Luz, Otávio Bianchi, Sandro Campos Amico, Fernanda T. G. Dias   +3 more
wiley   +1 more source

A novel VIVO–pyrimidinone complex: synthesis, solution speciation and human serum protein binding [PDF]

, 2013
The pyrimidinones mhcpe, 2-methyl-3H-5-hydroxy-6-carboxy-4-pyrimidinone ethyl ester (mhcpe, 1), 2,3- dimethyl-5-benzyloxy-6-carboxy-4-pyrimidinone ethyl ester (dbcpe, 2) and N-methyl-2,3-dimethyl-5- hydroxy-6-carboxyamido-4-pyrimidinone (N-MeHOPY, 3 ...
Avecilla, Fernando, Castro, M. M. C. A., Correia, Isabel, Garcia, M. Helena V., Gonçalves, Gisela, Jakusch, Támas, Kiss, Támas, Maestro, Miguel, Palacio, Lorena, Pessoa, João Costa, Tomaz, Isabel, Vieiros, Luís F.   +11 more
core   +1 more source

Controlling the Assembly of Ureido‐Pyrimidinone Supramolecular Monomers by Tuning the Hydrophilic‐Hydrophobic Balance

Journal of Polymer Science, Volume 64, Issue 3, Page 682-690, 1 February 2026.
In this study, the self‐assembly behavior of water‐compatible UPy‐based supramolecular monomers with varying hydrophilic‐hydrophobic balances is systematically investigated. Experimental and computational analyses reveal that the molecular monomer design is pivotal in steering the self‐assembly properties, highlighting the role of alkyl‐urea spacers in
Riccardo Bellan, Annalisa Cardellini, Claudio Perego, Lars J. M. M. Paffen, Laura Rijns, Giovanni M. Pavan, Patricia Y. W. Dankers   +6 more
wiley   +1 more source

Synthesis of thiophene and N-substituted thieno[3,2-d] pyrimidine derivatives as potent antitumor and antibacterial agents

Acta Pharmaceutica, 2017
A novel series of carbamothioylamino-benzene-sulfonamide-thiophene-carboxylates 4a-c and thieno[3,2-d]pyrimidin-2-yl-amino-benzene-sulfonamides 5a-c were synthesized in a series of synthetic steps and were used as key intermediates for the synthesis of ...
Hafez Hend N., Alsalamah Sulaiman A., El-Gazzar Abdel-Rhman B. A.   +2 more
doaj   +1 more source

Aza-Michael mono-addition using acidic alumina under solventless conditions [PDF]

, 2016
Aza-Michael reactions between primary aliphatic and aromatic amines and various Michael acceptors have been performed under environmentally-friendly solventless conditions using acidic alumina as a heterogeneous catalyst to selectively obtain the ...
Abdilla, Roderick, Bosica, Giovanna
core   +2 more sources

Unraveling Network Pharmacology‐Based Therapeutics of Anthranilate Sulfonamides via Sirtuins/FOXO3a Cascade in Alzheimer's Disease

Journal of Neurochemistry, Volume 170, Issue 2, February 2026.
Anthranilates sulfonamides (SA1–4) showed neuroprotective activity against human neuronal SH‐SY5Y cells under oxidative stress. The data represented significantly regulated sirtuins (SIRTs)/forkhead box class O 3a (FOXO3a)‐mediated longevity signaling pathway via targeting endogenous antioxidant enzymes, including superoxide dismutase 2 (SOD2) and ...
Waralee Ruankham, Veda Prachayasittikul, Ratchanok Pingaew, Wilasinee Jeungprasopsuk, Tanawut Tantimongcolwat, Virapong Prachayasittikul, Supaluk Prachayasittikul, Kamonrat Phopin   +7 more
wiley   +1 more source

The Redox Properties of Polyphenols and Their Role in ROS Generation for Biomedical Applications

Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.
The dual redox nature of polyphenols enables antioxidant activity and controlled reactive oxygen species (ROS) generation. This review details the biomedical applications of polyphenols in materials such as nanoparticles, coatings, and hydrogels for antimicrobial, tissue regeneration, and cancer therapies.
Jose Bolaños‐Cardet, Belén Pepió‐Tárrega, Javier Saiz‐Poseu, Alba López‐Moral, Faiz Ullah, Victor J. Yuste, Daniel Ruiz‐Molina, Salvio Suárez‐García   +7 more
wiley   +1 more source

Sigmatropic rearrangements in 5-allyloxytetrazoles [PDF]

, 2011
Mechanisms of thermal isomerization of allyl tetrazolyl ethers derived from the carbocyclic allylic alcohols cyclohex-2-enol and 3-methylcyclohex-2-enol and from the natural terpene alcohol nerol were investigated.
Abell, Abramovitch, Amin Ismael, Araújo, Araújo, Barkley, Basch, Becke, Bugalho, Bugalho, Cristiano, Cristiano, Cristiano, Cristiano, Daniela V. Coelho, Desarro, Dąbkowska, Frija, Frija, Frija, Frija, Frija, Frija, Frisch, Gu, Gómez-Zavaglia, Hashimoto, Head-Gordon, Igor Reva, Johnstone, Koldobskii, Lee, Luís M. T. Frija, M. Lurdes S. Cristiano, Mavromoustakos, McCarthy, Mishra, Pacios, Peng, Peng, Rui Fausto, Sandmann, Tamura, Toney   +43 more
core   +1 more source

Identification of Novel Class of Triazolo-Thiadiazoles as Potent Inhibitors of Human Heparanase and their Anticancer Activity

BMC Cancer, 2017
Background Expression and activity of heparanase, an endoglycosidase that cleaves heparan sulfate (HS) side chains of proteoglycans, is associated with progression and poor prognosis of many cancers which makes it an attractive drug target in cancer ...
C. P. Baburajeev, Chakrabhavi Dhananjaya Mohan, Shobith Rangappa, Daniel J. Mason, Julian E. Fuchs, Andreas Bender, Uri Barash, Israel Vlodavsky, Basappa, Kanchugarakoppal S. Rangappa   +9 more
doaj   +1 more source

Diels-alder cycloaddition of 2-azadienes to methyl 2-(2,6-dichlorophenyl)-2H-azirine-3-carboxylate in the synthesis of methyl 4-oxo-1,3-diazabicyclo[4.1.0]heptane-6-carboxylates [PDF]

, 2004
A number of fused 4-oxo-1,3-diazabicyclo[4.1.0]heptane-6-carboxylates, a new type of compound, have been obtained by Diels-Alder cycloaddition between nucleophilic 2-azadienes and an electrophilic 2H-azirine.
Alves, M. José, Durães, M. Miguel, Fortes, A. Gil   +2 more
core   +1 more source