A green and facile saccharin-catalyzed procedure is developed for the one-pot convenient synthesis of dihydropyrano[2,3-c]pyrazole, tetrahydrobenzo[b]pyran and pyrano[2,3-d]pyrimidinone scaffolds via multi-component tandem Knoevenagel cyclocondensation ...
Farzaneh Mohamadpour +2 more
doaj +1 more source
RECENT ADVANCES IN METAL-CATALYZED C-H FUNCTIONALIZATION OF PYRIMIDINONES, QUINAZOLINONES AND FUSED QUINAZOLINONES [PDF]
International audienceThis review emphasises the recent developments in metal-catalyzed functionalization using direct C-H bond activation of pyrimidinones (uracils), quinazolinones and quinazolinone-based fused poly-N-heterocycles as well as metal ...
Besson, Thierry, Fruit, Corinne
core +3 more sources
International audienceVariously substituted novel dihydropyridoazepinones have been prepared by an intermolecular radical addition followed by a radical cyclisation on a pyridine ring. The latter process involved the use of a combination of two different
Botez, I. +3 more
core +3 more sources
NITROIMIDAZOLES XI1 [I]: SYNTHESES OF TRISUBSTITUTED PYRAZOLES AND SUBSTITUTED (1 -METHYL-5-NITRO-2- IMIDAZOLYL) PYRIMIDINONES [PDF]
The reaction of P-diketones 1 with phenyl hydrazine afforded 5-aryl-3-(1- methyl-5-nitro-2-imidazoly1)-1-phenylpyrazole (2) and 3-aryl-5-(1-methyl-5- nitro-2-imidazoly1) -1-phenylpyrazole (3).
doaj
Green Synthesis of Pyrazol‑chromeno[2,3‑d]pyrimidinones Using SBA-Pr-SO3H as an Efficient Nanocatalyst [PDF]
Hexagonal mesoporous silica (SBA-15) was prepared and then functionalized by(3-mercaptopropyl)trimethoxysilane. The obtained 3-mercaptopropyl functionalized SBA-15 (SBA-Pr-SH) was then oxidized using H2O2 in methanol under an acidic condition to give ...
Ghodsi Mohammadi Ziarani +4 more
doaj
A new, simple thermally efficient and solvent-free condensation of 2-amino-3-cyano-6-methyl-4-phenyl-4H-pyran-5-ethylcarboxylate derivatives with coumarin-3-carboxylic acid employing pentafluorophenylammonium triflate (PFPAT) as an inexpensive ...
Majid Ghashang +2 more
doaj +1 more source
Plasmodium falciparum Hsp70-z, an Hsp110 homologue, exhibits independent chaperone activity and interacts with Hsp70-1 in a nucleotide-dependent fashion [PDF]
The role of molecular chaperones, among them heat shock proteins (Hsps), in the development of malaria parasites has been well documented. Hsp70s are molecular chaperones that facilitate protein folding.
Addmore Shonhai +5 more
core +2 more sources
Catalyzed Methods to Synthesize Pyrimidine and Related Heterocyclic Compounds [PDF]
This review covers articles published in the period from 2010 to mid-2022 on synthetic advances in the formation of pyrimidine and related heterocyclic compounds.
Algarra, Manuel +5 more
core
Studies on the properties and reactions of 1-ary1-2(1h)-pyrimidinones [PDF]
Thesis--University of Tsukuba, D.Sc.(A), no. 137, 1982.
Kato Akira, 加藤 明良
core
One- Pot synthesis and reactions of Novel 5-(4-fluoro-phenyl)-3-(8-hydroxyquinolin-5- yl)-7-phenyl-5H-thiazolo[3,2-a]pyrimidine-6- carbonitrile as antimicrobial agents [PDF]
The synthesis of 5-(4-fluoro-phenyl)-3-(8-hydroxyquinolin-5-yl)-7-phenyl-5H-thiazolo[3,2-a]pyrimidine-6-carbonitrile 4 was achieved by one-potthree-component synthesis using p-TSA (10 mol %) in refluxing CH3CN.
Abdelmohsen, S.A.
core +1 more source

