Discovering The New Chemical Entities of Therapeutic Interest [PDF]
, 2005 Not ...
Vagadia, Harsha C.
core
A green method for the synthesis of isoxazolyl aryl thieno[2,3-d]pyrimidinones using reusable polyethylene glycol as simple solvent catalyst and evaluation of anti-microbial activity [PDF]
, 2022 336-347Novel series of isoxazolyl aryl thieno[2,3-d]pyrimidinones 4 have been synthesized from (E)-2-amino-5-(3-methyl-4- nitroisoxazol-5-yl)-N-(3-methyl-5-styrylisoxazol-4-yl)-4-arylthiophene-3-carboxamide synthon 3. Compound 3 is obtained by reaction
Dharavath, Nagaraju +2 more
core
A simple and efficient one-pot synthesis of novel benzimidazo[1,2-a]- chromeno[4,3-d] pyrimidinones catalyzed by [Et3NH][HSO4] [PDF]
, 2020 1418-1424A simple and efficient one-pot synthesis of novel polyheterocyclic benzimidazo[1,2-a]- chromeno[4,3-d]pyrimidinones 4 via a three-component condensation of 2-aminobenzimidazole 1, aromatic aldehydes 2 and 4-hydroxy coumarin 3 catalyzed by ...
Brahmeshwari, G, Kishore, B, Prasoona, G
core +3 more sources
Green Synthesis of Pyrazol‑chromeno[2,3‑d]pyrimidinones Using SBA-Pr-SO3H as an Efficient Nanocatalyst [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2017 Hexagonal mesoporous silica (SBA-15) was prepared and then functionalized by(3-mercaptopropyl)trimethoxysilane. The obtained 3-mercaptopropyl functionalized SBA-15 (SBA-Pr-SH) was then oxidized using H2O2 in methanol under an acidic condition to give ...
Ghodsi Mohammadi Ziarani +4 more
doaj
, 2011 An efficient synthesis of nitrogen-containing heterocycles pyrazole, triazole, pyridinone and pyrimidinone derivatives from ethyl 3-(6-dibenzothiophen-2-yl-pyridazin-3-ylamino)-3-oxopropanoate (2) was described.
Bloomer, Donia, Issac, Ungureanu
core +1 more source
Pyrimidinone: versatile Trojan horse in DNA photodamage?
Photochemical & Photobiological Sciences, 2015 Abstract (6-4) Photolesions between adjacent pyrimidine DNA bases are prone to secondary photochemistry. It has been shown that singlet excited (6-4) moieties form Dewar valence isomers as well as triplet excitations. We here report on the triplet state of a minimal model for the (6-4) photolesion, 1-methyl-2(1H)-pyrimidinone.
Christian Torres Ziegenbein +3 more
openaire +3 more sources
Highly regioselective 6-exo-dig iodo/bromo cyclizations of functionalized 5-amino propargyl pyrimidinones: an efficient synthesis of functionalized pteridines. [PDF]
RSC Adv, 2023 Naikoo RA +4 more
europepmc +1 more source
Direct Chemoselective Synthesis of N-3-Substituted Pyrimidinones in a Microwave-Assisted Method
, 2015 Synthesis of selectively N-3-substituted pyrimidine nucleobases or pyrimidinones has always been a challenge because of poor regioselectivity and chemoselectivity.
B. Laxminarayana, L. Kundu
semanticscholar +1 more source
Ethyl 4-[3,5-bis(trifluoromethyl)phenyl]-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate [PDF]
, 2009 In the title compound, C16H14F6N2O3, the dihydropyrimidinone ring adopts an envelope conformation. In the crystal, molecules are linked by N—H⋯O and C—H⋯O hydrogen bonds into a ribbon-like structure along the b axis.
Allen +15 more
core +3 more sources
, 2014 A straightforward method has been developed for the synthesis of 1-phenyl-imidazo [2,1-c][1,2,4]triazole derivatives 5a–j and 1-phenyl-[1,2,4]triazolo[4,3-a]pyrimidinones derivatives 6a–g starting from 5-amino-1-phenyl[1,2,4]triazole and p ...
Monia Aouali +5 more
semanticscholar +1 more source