Results 81 to 90 of about 3,593 (197)

Metal complexes of pyrimidinones

, 1977
Imperial Users ...
Johns, Keith William, Johns, Keith William   +1 more
openaire   +1 more source

Design, Synthesis, Antimicrobial Activity, and Molecular Docking of Novel Thiazoles, Pyrazoles, 1,3-Thiazepinones, and 1,2,4-Triazolopyrimidines Derived from Quinoline-Pyrido[2,3-d] Pyrimidinones

Pharmaceuticals
Background: Recently, pyrido[2,3-d] pyrimidine, triazolopyrimidine, thiazolopyrimidine, quinoline, and pyrazole derivatives have gained attention due to their diverse biological activities, including antimicrobial, antioxidant, antitubercular, antitumor,
Ameen Ali Abu-Hashem, Sami A. Al-Hussain
doaj   +1 more source

Иодирование аминопроизводных азотсодержащих гетероциклов под действием Me[4]N{+}ICl[2]{-}/AgNO{3} в метаноле [PDF]

, 2009
Исследована активность тетраметиламмоний иоддихлорида в присутствии нитрата серебра в растворе метанола для электрофильного иодирования аминопроизводных азотсодержащих гетероциклов ряда пиридина, пиримидина, хинолина. Реакция иодирования протекает при 20
Краснокутская, Елена Александровна, Лесина, Юлия Александровна, Третьяков, Алексей Николаевич   +2 more
core  

HIGHLIGTHS IN 1,2,3-DITHIAZOLE CHEMISTRY [PDF]

, 2010
Among the five-membered heterocycles containing nitrogen and sulphur atoms, 1,2,3-dithiazoles are important compounds due to their unusual physical properties, biological activity and versatile chemistry.
Emmanuel Deau, Hervé Rouillard, Hélène Laborie, Jean-René Chérouvrier, Lisianne Domon, Philippe Pineau, Valérie Thiéry   +6 more
core  

Chimeric design, synthesis, and biological assays of a new nonpeptide insulin-mimetic vanadium compound to inhibit protein tyrosine phosphatase 1B [PDF]

, 2010
Prior to its total synthesis, a new vanadium coordination compound, called TSAG0101, was computationally designed to inhibit the enzyme protein tyrosine phosphatase 1B (PTP1B). The PTP1B acts as a negative regulator of insulin signaling by blocking the
Do, Quoc Tuan, FJ, Melendez, H Abdallah, Hassan, José Antonio, Guevara García, Philippe, Bernard, Thomas, Scior   +5 more
core  

Cycloaddition reactions of conjugated azoalkenes [PDF]

, 2012
An overview of the use of 2H-azirines, conjugated nitrosoalkenes and conjugated azoalkenes bearing phosphorus substituents in addition and cycloaddition reactions is presented, focused on strategies for the synthesis of aminophosphonate and ...
Lemos, A.
core  

Investigation of structural effects on the reactivity of heterocyclic bioactive compounds [PDF]

, 2008
Tese de dout., Química, Faculdade de Ciências e Tecnologia, Universidade do Algarve, 2008In the course of this investigation, structural effects on the reactivity of a series of heterocyclic compounds, in particular tetrazole and benzisothiazole ...
Frija, L.
core  

In silico Design and Synthesis of Tetrahydropyrimidinones and Tetrahydropyrimidinethiones as Potential Thymidylate Kinase Inhibitors Exerting Anti-TB Activity Against Mycobacterium tuberculosis

Drug Design, Development and Therapy, 2020
Katharigatta N Venugopala, 1, 2 Christophe Tratrat, 1 Melendhran Pillay, 3 Sandeep Chandrashekharappa, 4 Omar Husham Ahmed Al-Attraqchi, 5 Bandar E Aldhubiab, 1 Mahesh Attimarad, 1 Osama I Alwassil, 6 Anroop B Nair, 1 Nagaraja Sreeharsha, 1 Rashmi ...
Venugopala KN, Tratrat C, Pillay M, Chandrashekharappa S, Al-Attraqchi OHA, Aldhubiab BE, Attimarad M, Alwassil OI, Nair AB, Sreeharsha N, Venugopala R, Morsy MA, Haroun M, Kumalo HM, Odhav B, Mlisana K   +15 more
doaj  

Highly regioselective 6-exo-dig iodo/bromo cyclizations of functionalized 5-amino propargyl pyrimidinones: an efficient synthesis of functionalized pteridines. [PDF]

RSC Adv, 2023
Naikoo RA, Kumar R, Sharma R, Mahajan D, Bhargava G.   +4 more
europepmc   +1 more source

Design and Synthesis of Chemical Entities of Therapeutic Interest [PDF]

, 2005
Not ...
chovatia, Prafulkumar T.
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