Results 201 to 210 of about 83,545 (299)

Correction: Uric acid promotes myocardial infarction injury via activating Pyrin domain-containing 3 inflammasome and reactive oxygen species/transient receptor potential melastatin 2/Ca2 + pathway. [PDF]

BMC Cardiovasc Disord
Wu H, Dai R, Wang M, Chen C.
europepmc   +1 more source

Chronic Pain: Epidemiology, Pathophysiology, and Clinical Management

MedComm, Volume 7, Issue 5, May 2026.
The multidimensional nature of chronic pain is illustrated through four interconnected domains. (Left) Epidemiology and Global Burden: Chronic pain affects approximately one in five individuals globally, contributing to a rising trend in disability‐adjusted life years (YLDs) and a significant socioeconomic impact.
Zhihao Shang, Zijiao Tian, Zhaoquan Wang, Zerui Yang, Ziyao Wang, Zikang Wang, Ziqing Wang, Xingyuan He, Yu Yan, Yuanfeng Gong, Siyuan Xu, Xinyi Li, Guihua Tian   +12 more
wiley   +1 more source

Gut microbiota alliance to shape sceneries of familial Mediterranean fever: a scoping review detailing difference between children and adults. [PDF]

Front Immunol
Pisa CM, Verrone A, Mazuy M, Ientile L, Rigante D, Esposito S.   +5 more
europepmc   +1 more source

FERM domain containing kindlin 1 knockdown attenuates inflammation induced by intracerebral hemorrhage in rats via NLR family pyrin domain containing 3/nuclear factor kappa B pathway

, 2023
Jian-Qiang Wei, Jing Yin, Ying Cui, Kaijie Wang, Ming-Yan Hong, Jianzhong Cui   +5 more
openalex   +2 more sources

The Evolving Therapeutic Landscape of Gallic Acid: A Review of Mechanistic Insights and Clinical Potential

Molecular Nutrition &Food Research, Volume 70, Issue 9, 13 May 2026.
ABSTRACT Gallic acid (GA), a plant‐derived phenolic compound, is evolving from a general antioxidant into a specific molecular modulator and a functional building block for advanced biomedical materials. This review synthesizes recent insights underpinned by GA's “redox duality”—its capacity to act as either a radical scavenger or a pro‐oxidant.
Woo Hyun Park
wiley   +1 more source

Interleukin-18: A Critical Culprit in Inflammatory Renal Disease. [PDF]

Kidney Int Rep
Sergi CM.
europepmc   +1 more source

Betulin Protects Against Cardiac Hypertrophy by Improving AMPK/Nrf2‐Dependent Mitochondrial Function

Phytotherapy Research, Volume 40, Issue 5, Page 2878-2894, May 2026.
Betulin effectively mitigates pressure overload‐induced cardiac hypertrophy in both Ang II‐infused and TAC‐operated mice. Mechanistically, betulin activated AMPK phosphorylation, promoted Nrf2 nuclear translocation, and upregulated antioxidant genes (HO‐1 and NQO‐1), thereby restoring mitochondrial function in cardiomyocytes.
Bei Zheng, Mingyang He, Haiying Wu, Tianjie Zhang, Yuxia Jiang, Chuanwei Xin, Meiling Zhang, Jiaqi He, Lulu Zheng   +8 more
wiley   +1 more source

Hidradenitis suppurativa with systemic autoinflammatory features in patients of Moroccan origin: case report and implications for personalized medicine. [PDF]

Front Immunol
Lurel J, El Aissoug F, Hammoud FZ, Mintoff D, Benhadou F.   +4 more
europepmc   +1 more source

Emerging Role of Ferroptosis in Diabetes and Associated Complications: When Metabolic Dysregulation Meets Cell Death

Cell Proliferation, Volume 59, Issue 5, May 2026.
This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang, Ying Zhang, Yue Xu, Mengyuan Yang, Yuan Wei, Yuan Li, Tongyue Yang, Xu Wang, Chaona Yang, Qi Feng, Guolan Xing   +10 more
wiley   +1 more source

A novel pathogenic variant in PSTPIP1 highlights the diversity of PSTPIP1-associated disorders. [PDF]

Rheumatology (Oxford)
Farajzadeh N, Triaille C, Monjarret B, Lamothe S, Touzot F, Cros G.   +5 more
europepmc   +1 more source