Results 51 to 60 of about 85,504 (285)

The Synthesis of Pyrroles from Nitroolefins

Журнал органічної та фармацевтичної хімії
The synthesis of pyrroles occupies a key place in synthetic organic chemistry due to the numerous biological properties of pyrrole derivatives, in particular antimicrobial, antibacterial, antifungal, antimalarial, anticancer activities, etc.
Andrii H. Hotynchan, Olena M. Kovtun, Yuriy P. Kovtun   +2 more
doaj   +1 more source

Cycloaddition of Benzyne with Alkoxy-Substituted Pyrroline-N-oxides­: Unexpected Rearrangement to an N-Phenylpyrrole

SynOpen, 2018
Reaction of enantiopure 3,4-dialkoxy-pyrroline N-oxides with benzyne affords the expected tetrahydrobenzo[d]pyrrolo[1,2-b]isoxazoles along with an unexpected 2,3-disubstitued-N-phenyl-pyrrole derived from an unprecedented rearrangement of the adduct of ...
Franca M. Cordero, Bhushan B. Khairnar, Anna Ranzenigo, Alberto Brandi   +3 more
doaj   +1 more source

Synthesis and Anti-Tuberculosis Activity of Substituted 3,4-(dicoumarin-3-yl)-2,5-diphenyl Furans and Pyrroles

Engineering Proceedings, 2022
Increasing rates of multi-drug resistant (MDR) and extremely-drug resistant (XDR) cases of tuberculosis (TB) strains are alarming, and eventually hampered an effective control of the pathogenic disease. In the present study, nine derivatives of 2,3-bis(2-
Bhagwat Jadhav, Ramesh Yamgar, Suraj N. Mali   +2 more
doaj   +1 more source

Synthesis and Pharmacochemistry of New Pleiotropic Pyrrolyl Derivatives

Molecules, 2015
Within the framework of our attempts to synthesize pleiotropic anti-inflammatory agents, we have synthesized some chalcones and their corresponding 3,4-pyrrolyl derivatives. Chalcones constitute a class of compounds with high biological impact.
Markella Konstantinidou, Alice Gkermani, Dimitra Hadjipavlou-Litina   +2 more
doaj   +1 more source

Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis. [PDF]

, 2016
The use of photochemical transformations is a powerful strategy that allows for the formation of a high degree of molecular complexity from relatively simple building blocks in a single step. A central feature of all light-promoted transformations is the
Kärkäs, Markus D., Porco, John A., Stephenson, Corey R.J.   +2 more
core   +2 more sources

Synthetic Approaches to the Lamellarins—A Comprehensive Review

Marine Drugs, 2014
The present review discusses the known synthetic routes to the lamellarin alkaloids published until 2014. It begins with syntheses of the structurally simpler type-II lamellarins and then focuses on the larger class of the 5,6-saturated and -unsaturated ...
Dennis Imbri, Johannes Tauber, Till Opatz   +2 more
doaj   +1 more source

From conjugated tertiary skipped diynes to chain-functionalized tetrasubstituted pyrroles [PDF]

, 2016
A novel and metal-free method for the synthesis of chain-functionalized tetrasubstituted pyrroles from easily accessible tertiary skipped diynes, was reported.
García-Tellado, Fernando, González-Platas, Javier, López-Tosco, Sara, Tejedor, David   +3 more
core   +1 more source

A Novel Indium-Catalyzed Three-Component Reaction: General and Efficient One-Pot Synthesis of Substituted Pyrroles [PDF]

, 2011
A convenient and general approach towards the synthesis of substituted pyrroles from propargylic acetates, silyl enol ethers, and primary amines was described. This novel transformation was catalyzed by indium trichloride in a one-pot synthesis, and high
Hao, Lu, Lin, Min, Ma, Rui-da, Zhan, Zhuang-ping, 詹庄平   +4 more
core   +1 more source

[3+3]-Annulation of Cyclic Nitronates with Vinyl Diazoacetates: Diastereoselective Synthesis of Partially Saturated [1,2]Oxazino[2,3-b][1,2]oxazines and Their Base-Promoted Ring Contraction to Pyrrolo[1,2-b][1,2]oxazine Derivatives

Molecules, 2023
A rhodium(II)-catalyzed reaction of cyclic nitronates (5,6-dihydro-4H-1,2-oxazine N-oxides) with vinyl diazoacetates proceeds as a [3+3]-annulation producing bicyclic unsaturated nitroso acetals (4a,5,6,7-tetrahydro-2H-[1,2]oxazino[2,3-b][1,2]oxazines ...
Yulia A. Antonova, Yulia V. Nelyubina, Sema L. Ioffe, Andrey A. Tabolin   +3 more
doaj   +1 more source

Synthesis of Non-Aromatic Pyrroles Based on the Reaction of Carbonyl Derivatives of Acetylene with 3,3-Diaminoacrylonitriles

Molecules, 2023
The reaction of 3,3-diaminoacrylonitriles with DMAD and 1,2-dibenzoylacetylene was studied. It is shown that the direction of the reaction depends on the structure both of acetylene and of diaminoacrylonitrile. In the reaction of DMAD with acrylonitriles
Pavel S. Silaichev, Lidia N. Dianova, Tetyana V. Beryozkina, Vera S. Berseneva, Andrey N. Maslivets, Vasiliy A. Bakulev   +5 more
doaj   +1 more source