Results 1 to 10 of about 81,237 (352)
Biosynthesis of the pyrrolidine protein synthesis inhibitor anisomycin involves novel gene ensemble and cryptic biosynthetic steps [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2017 Xiaoqing Zheng +10 more
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Recent Developments in Azomethine Ylide-Initiated Double Cycloadditions [PDF]
MoleculesAzomethine ylides (AMYs) have a nitrogen–carbon double bond and an electron lone pair on the nitrogen atom. They are essential 1,3-dipoles for [3+2] cycloadditions in the synthesis of pyrrolidine-containing heterocycles.
Tieli Zhou +4 more
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Nylon 4,I: an amorphous polyamide [PDF]
, 1984 The melt polymerization of nylon 4, I was studied, starting with nylon-salt and nylon prepolymers (ηinh=0.25). With nylon-salt only low molecular polymers were obtained, while with prepolymers the inherent viscosity could be raised to 0.77 (3h, 270°, vac.
Gaymans, R.J., Ham, A.G.J. van der
core +20 more sources
Therapeutic potential of pyrrole and pyrrolidine analogs: an update
Molecular diversity, 2022 The chemistry of nitrogen-containing heterocyclic compound pyrrole and pyrrolidine has been a versatile field of study for a long time for its diverse biological and medicinal importance .
N. Jeelan Basha +2 more
semanticscholar +1 more source
Recent insights about pyrrolidine core skeletons in pharmacology
Frontiers in Pharmacology, 2023 To overcome numerous health disorders, heterocyclic structures of synthetic or natural origin are utilized, and notably, the emergence of various side effects of existing drugs used for treatment or the resistance of disease-causing microorganisms ...
S. Poyraz +4 more
semanticscholar +1 more source
Pyrrolidine in Drug Discovery: A Versatile Scaffold for Novel Biologically Active Compounds
Topics in current chemistry, 2021 The five-membered pyrrolidine ring is one of the nitrogen heterocycles used widely by medicinal chemists to obtain compounds for the treatment of human diseases.
Giovanna Li Petri +5 more
semanticscholar +1 more source
Symmetry, 2021 A series of new spiro-heterocycles engrafted spirooxindole/pyrrolidine/thiochromene scaffolds was synthesized by the three-component 1,3-dipolar cycloaddition reactions in a fully controlled regio- and stereo-selective fashion.
A. Barakat +7 more
semanticscholar +1 more source
(Z)-1-Benzyl-5-(4-bromophenyl)-5-hydroxy-4-(2-oxomorpholin-3-ylidene)pyrrolidine-2,3-dione
Molbank, 2023 The reaction of 8-(4-bromobenzoyl)-3,4-dihydro-1H-pyrrolo[2,1-c][1,4]oxazine-1,6,7-trione with benzylamine in acetonitrile at room temperature afforded a good yield of (Z)-1-benzyl-5-(4-bromophenyl)-5-hydroxy-4-(2-oxomorpholin-3-ylidene)pyrrolidine-2,3 ...
Nikita A. Tretyakov, Andrey N. Maslivets
doaj +1 more source
Acta Crystallographica Section E Structure Reports Online, 2012 In the title compound, C(4)H(5)NO(2), the non-H atoms are nearly coplanar, with a maximum deviation of 0.030 (1) Å. In the crystal, pairs of mol-ecules are linked by N-H⋯O hydrogen bonds into inversion dimers.
Min Yu, Xing Huang, Feng Gao
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[(Pyrrolidin-1-yl)carbothioylsulfanyl]methyl pyrrolidine-1-carbodithioate [PDF]
Acta Crystallographica Section E Structure Reports Online, 2010 The title compound, C(11)H(18)N(2)S(4), was unexpectedly obtained during studies on the reactivity of the complex tris-(acac-κ(2)O,O')gallium(III) (acac is acetyl-acetonate) with C(4)H(8)NCS(2)H in dichloro-methane. The title compound shows disordered two pyrrolidine rings with major and minor occupancies of 0.546 (4) and 0.454 (4).
Yen-Hsiang Huang +4 more
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