Results 101 to 110 of about 33,483 (272)

A Phenyl-Pyrrolidine Derivative Reveals a Dual Inhibition Mechanism of Myocardial Mitochondrial Permeability Transition Pore, Which Is Limited by Its Myocardial Distribution [PDF]

, 2020
Mathieu Panel, Abdelhakim Ahmed‐Belkacem, Isaac Ruiz, Jean‐François Guichou, Jean–Michel Pawlotsky, Bijan Ghaleh, Didier Morin   +6 more
openalex   +1 more source

The impact of tobacco cessation on buccal mucosa cancer risk: A multi‐centre case–control study in India

International Journal of Cancer, Volume 159, Issue 2, Page 368-377, 15 July 2026.
What's new? While the association between tobacco consumption and oral cancer is well established, the effect of cessation, particularly of chewing tobacco, the most common tobacco product in South Asia, is understudied. This case–control study in an Indian population demonstrates that a longer duration of tobacco smoking and chewing cessation is ...
Gayathri B. Pullat, Bastian Bohrmann, Grace Sarah George, Shubham Dikshit, Arjun Singh, Pankaj Chaturvedi, Rajesh Dikshit, Sarah Lewington, Sharayu Mhatre   +8 more
wiley   +1 more source

Structure-Activity relationship of 1-(Furan-2ylmethyl)Pyrrolidine-Based Stimulation-2 (ST2) inhibitors for treating graft versus host disease

, 2022
Xinrui Yuan, Hua Jiang, Denggang Fu, Aaron M. Robida, Krishani Rajanayake, Hebao Yuan, Bo Wen, Duxin Sun, Brennan T. Watch, Krishnapriya Chinnaswamy, Jeanne A. Stuckey, Sophie Paczesny, Jason C. Rech, Chao‐Yie Yang   +13 more
openalex   +2 more sources

Molecular Hybridization of Clinically Relevant P2X7 Antagonists

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
We employed a molecular hybridization strategy, combining clinically validated antagonists AZD‐9056 and JNJ‐54175446, to design and synthesize a library of novel adamantane‐containing P2X7R antagonists. Pharmacological and in silico analyses indicate that these adamantyl hybrids adopt a distinct, shallow binding mode within the P2X7R allosteric pocket,
Nicholas B. Lynch, Charleigh T. A. Agius, André D. J. McKenzie, Jessica O’Driscoll, Angus Tolmie, Taylor R. Garrett, Eryn Werry, Michael Kassiou   +7 more
wiley   +1 more source

A modular and divergent approach to spirocyclic pyrrolidines

, 2020
Benjamin D. A. Shennan, P. W. Smith, Yusuke Ogura, Darren J. Dixon   +3 more
openalex   +2 more sources

Crystal structure of 6-methyl-3-(pyrrolidine-1-carbonyl)-2H-chromen-2-one, C₁₅H₁₅N₁O₃ [PDF]

, 2022
Jie Wang, Li-Sha Luo, Yu-Cong Deng, Zhong-Chao Li, Da‐Yong Peng   +4 more
openalex   +1 more source

Closing the Carbon Loop: Continuous‐Flow Synthesis of N‐Aroyl Sulfoximines via Electrochemical CO2 Reduction

ChemSusChem, Volume 19, Issue 13, 14 July 2026.
A modular continuous‐flow platform enables the Pd‐catalyzed carbonylative N‐aroylation of sulfoximines using carbon monoxide (CO) generated on demand from carbon dioxide (CO2) via solid oxide electrolysis cell (SOEC). The integration of a heterogeneous palladium catalyst and a biomass‐derived solvent provides a safe, scalable, and sustainable route to ...
Giada Moroni, Maximilian Weiss, Giulia Russo, Gloria Biscontini, Olga Lanaridi, Andreas Limbeck, Tobias Huber, Alexander Karl Opitz, Katharina Bica‐Schröder   +8 more
wiley   +1 more source

Synthesis of Pyrrolidine Derivatives with Pharmacological Activity. IX. Synthesis of 1, 1, 5-Trimethyl-2-ethyl-and 1, 1, 2, 4, 5-Pentamethyl-3-diphenylmethylenepyrrolidinium Iodide as Potential Anticholinergic Agents

, 1976
S. OHKI, Yuichiro Yabe, N. OZAWA, Fumiko Hamaguchi   +3 more
openalex   +2 more sources

On the Planarity of Heterocyclic Bay‐Substituted Perylenediimides: Insight into the Fluorescent Photoinduced Electron Transfer Sensing Framework

European Journal of Organic Chemistry, Volume 29, Issue 26, 13 July 2026.
Near‐infrared fluorescent pH indicators based on perylenediimide were constructed in a modular receptor–spacer–fluorophore–spacer–receptor format with heterocyclic amino moieties at the bay positions. Counterintuitively, the dibrominated intermediate with two heavy atoms is more emissive than the heterocyclic compounds.
Luke Camenzuli, Davide Benedetto Tiz, Nicola’ Agius, Konrad Szaciłowski, David C. Magri   +4 more
wiley   +1 more source

Tetrasubstituted Pyrrolidines via a Tandem Aza‐Payne/Hydroamination Reaction.

, 2007
Jennifer M. Schomaker, Andrea R. Geiser, Rui Huang, Babak Borhan   +3 more
openalex   +2 more sources