Results 111 to 120 of about 81,237 (352)

A Self‐Healing Conductive PVP/SUM Hydrogel for Real‐Time Human Motion Detection

open access: yesNano Select, EarlyView.
The PVP/SUM hydrogel exhibits self‐healing, conductivity, and strong mechanical performance due to H‐bonds and dipole–dipole interactions. It elongates up to 330% and shows fracture strength between 0.9 and 1.5 MPa under varying strain rates. With a conductivity of 3.28 × 10−5 S/cm, it responds rapidly to human motion, enabling real‐time monitoring for
Vinnakoti Meghana, Illa Ramakanth
wiley   +1 more source

Room Temperature Synthesis and Antibacterial Activity of New Sulfonamides Containing N,N -Diethyl-Substituted AmidoMoieties [PDF]

open access: yes, 2012
Sulfonamide drugs which have brought about an antibiotic revolution in medicine are associated with a wide range of biological activities.
Ajani, Olayinka O.   +4 more
core   +5 more sources

Hydroxylated Pyrrolidines. Enantiospecific Synthesis of all-cis 2,3,4,5-Substituted Pyrrolidine Derivatives from Serine

open access: yesThe Journal of Organic Chemistry, 2002
We report the enantiospecific synthesis of the sterically congested all-cis 2,3,4,5-substituted pyrrolidines 4, 5, and 6, from either D- or L-serine. Hemiaminal intermediate 13 is converted to the fully substituted pyrrolidine 15 by way of a tandem Wittig-Michael reaction.
Verma, S.K.   +4 more
openaire   +4 more sources

Organocatalytic Doubly Annulative Approach to 3,4-Dihydrocoumarins Bearing a Fused Pyrrolidine Scaffold.

open access: yesJournal of Organic Chemistry, 2016
A new strategy for the highly enantio- and diastereoselective synthesis of 3,4-dihydrocoumarin derivatives bearing a fused pyrrolidine ring is reported.
D. Kowalczyk, Ł. Albrecht
semanticscholar   +1 more source

Microwave‐Assisted Organic Syntheses in Deep Eutectic Solvents: A Win‐Win Association for Sustainable Chemistry

open access: yesChemistryOpen, EarlyView.
In organic synthesis, deep eutectic solvents (DES) have demonstrated their ability to be used as reaction media for the development of reactions in line with green chemistry principles. This review presents an overview of microwave‐assisted organic synthesis in DES, highlighting the diversity of uses for these solvents, their role in mechanisms, the ...
Pierre‐Olivier Delaye   +2 more
wiley   +1 more source

Crystal structure of 1-[(2S*,4R*)-6-fluoro-2-methyl-1,2,3,4-tetrahydroquinolin-4-yl]pyrrolidin-2-one

open access: yesActa Crystallographica Section E, 2014
In the title compound, C14H17FN2O, the 1,2,3,4-tetrahydropyridine ring of the quinoline moiety adopts a half-chair conformation, while the pyrrolidine ring has an envelope conformation with the central methylene C atom as the flap.
P. S. Pradeep   +4 more
doaj   +1 more source

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

open access: yesChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel   +5 more
wiley   +1 more source

Gold-Catalyzed Intramolecular Aminoarylation of Alkenes: C-C Bond Formation through Bimolecular Reductive Elimination [PDF]

open access: yes, 2010
Gold-ilocks and the 3 mol % catalyst: Bimetallic gold bromides allow the room temperature aminoarylation of unactivated terminal olefins with aryl boronic acids using Selectfluor as an oxidant.
Benitez, Diego   +6 more
core   +1 more source

2,3‐Dichloro‐5,6‐Dicyano‐1,4‐Benzoquinone (DDQ)‐Mediated CC Bond Formation: Redox Strategies from Stoichiometric to Catalytic Systems

open access: yesChemistryOpen, EarlyView.
2,3‐Dichloro‐5,6‐dicyano‐1,4‐benzoquinone serves as a versatile oxidant and redox catalyst for CC bond formation through hydride abstraction or single‐electron transfer. Stoichiometric and catalytic systems enable benzylic, allylic, and aromatic CH activation under mild, metal‐free conditions, providing sustainable routes to complex and bioactive ...
Dohoon Cha, Sun‐Joon Min
wiley   +1 more source

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