Ximenia americana L. From Popular Use to Anti‐Inflammatory Activities: A Comprehensive Review
ABSTRACT Ximenia americana (L.), known as “yellow plum,” “sea lemon,” or “Brazilian plum,” is a tropical/subtropical plant widely used in traditional medicine. Its roots, leaves, flowers, stem, and fruits are traditionally employed to treat various inflammatory disorders.
Bruno Anderson F. Silva +9 more
wiley +1 more source
18F‐Radiopharmaceutical Diversification Enabled by Deaminative Cross‐Electrophile Couplings
A general Ni‐mediated (C)sp2–(C)sp3 cross‐coupling expedites access to 18F‐radiopharmaceuticals, essential for positron emission tomography imaging and drug discovery. This late‐stage diversification approach was implemented across three user‐friendly automated protocols affording 18F‐radiotracers in sufficient quantities for imaging.
Isabella F. Ogilvy +13 more
wiley +2 more sources
ABSTRACT A stability‐indicating UHPLC–MS method was developed to investigate the stress degradation behavior of eletriptan hydrobromide under ICH‐recommended acidic, alkaline, neutral, oxidative, thermal, and photolytic conditions. Significant degradation was observed only under acidic and oxidative stress.
Dastagiri Reddy Bhuma +3 more
wiley +1 more source
Bis(4-(3,4-dimethylenepyrrolidyl)-phenyl) methane [PDF]
It is the primary object of the present invention to prepare high temperature polymeric materials, especially linear aromatic polyimides, which maintain their integrity and toughness during long exposure times at elevated temperatures.
Ottenbrite, Raphael M.
core +2 more sources
Thiophenderivate als vielseitige Vorstufen für die Synthese von (Hetero)aromaten und Naturstoffen
Verborgen, aber leistungsstark: Thiophene und ihre gesättigten Analoga haben sich als vielseitige C4‐Bausteine erwiesen, die sich effektiv in der Naturstoffsynthese sowie beim Aufbau funktionalisierter (Hetero)aromaten einsetzen lassen. Dieser Minireview soll einen Überblick über Strategien zur Anwendung dieser schwefelhaltigen heterozyklischen ...
Anna Keimer, Franz‐Lucas Haut
wiley +1 more source
Taurine-Based Hybrid Drugs as Potential Anticancer Therapeutic Agents: In Vitro, In Vivo Evaluations
Background/Objectives: The development of antitumor agents possessing low toxicity against non-cancerous cells is still a challenge in medicinal chemistry. In this paper, we report the antitumor activity of “hybrid structures” derived from the amino acid
Saltanat Nakypova +17 more
doaj +1 more source
Stereochemical Studies on a New Ciramadol Analogue by NMR-Spectroscopy [PDF]
The absol. configuration of a Ciramadol analogue obtained from (-)-menthone is established by 'H-NMR-. simulated NMR-, COSY-90-, and NOEmeasurements. The final compound 2-(a-1 -pyrrolidino)benzy 1-4-isopropyl- 1 -methyl-cyclohexan-3-one (4b), e.g..
Akgün, H. +4 more
core
Thiophene Derivatives as Versatile Precursors for (Hetero)Arene and Natural Product Synthesis
Hidden but Powerful: Thiophenes and their saturated analogues have been demonstrated to be versatile C4‐building blocks that can be rapidly applied to natural product synthesis and the construction of functionalized (hetero)arenes. This minireview aims to provide a concise overview of the strategies and implementations of these sulfur‐containing ...
Anna Keimer, Franz‐Lucas Haut
wiley +1 more source
Redox-neutral α-functionalization of pyrrolidines: facile access to α-aryl-substituted pyrrolidines
Using a quinone monoacetal as the oxidant and DABCO as the base, we report the one-step synthesis of α-aryl-substituted pyrrolidines from pyrrolidine. The reaction of pyrrolidine and quinone monoacetal in 2,2,2-trifluoroethanol afforded octahydro-dipyrroloquinoline in high yield.
Feng-Xian Tian +4 more
openaire +2 more sources
ChemInform Abstract: An Organocatalytic Direct Mannich—Cyclization Cascade as [3 + 2] Annulation: Asymmetric Synthesis of 2,3‐Substituted Pyrrolidines. [PDF]
Indresh Kumar +3 more
openalex +1 more source

