Results 141 to 150 of about 70,546 (390)

Photoswitchable, Water‐Soluble Bisazobenzene Cross‐Linkers with Enhanced Properties for Biological Applications

ChemPhotoChem, Volume 6, Issue 12, December 2022., 2022
Photoswitchable cross‐linkers have the ability to connect two residues on a biomolecule, thereby causing large changes in the structure and function of the target upon irradiation. The design, synthesis and purification of cross‐linkers with large end‐to‐end distances remains challenging, especially for applications in chemical biology.
Jana Volarić, Sebastian Thallmair, Ben L. Feringa, Wiktor Szymanski   +3 more
wiley   +1 more source

Insights into the mechanism for gold catalysis: behaviour of gold(i) amide complexes in solution [PDF]

, 2013
We report the synthesis and activity of new mononuclear and dinuclear gold amide complexes . The dinuclear complexes and were characterised by single crystal X-ray analysis.
Alker, Bayler, Benitez, Berners-Price, Brandys, Brown, Chao, Delfs, Eddy M. E. Viseux, Forward, Frelek, Gao, Hashmi, Healy, Huo, Iain J. Day, Johnson Jr., Kanai, Kennedy-Smith, Khin, Macchioni, Mariusz Bobin, Mézailles, Nguyen, Nilsson, Noey, Saito, Schmidbaur, Schmidbaur, Stephen M. Roe, Teles, Toullec, Uson, Vicente, Vicente   +34 more
core   +1 more source

Plant enzyme reactions leading to the formation of heterocyclic compounds. 1. The formation of unsaturated pyrrolidine and piperidine compounds [PDF]

, 1955
P. J. Mann, W. R. Smithies
openalex   +1 more source

One-Pot Asymmetric Nitro-Mannich/Hydroamination Cascades for the Synthesis of Pyrrolidine Derivatives: Combining Organocatalysis and Gold Catalysis

ACS Catalysis, 2014
The highly enantioselective preparation of trisubstituted pyrrolidine derivatives employing a one-pot nitro-Mannich/hydroamination cascade is reported.
D. M. Barber, Andrej Ďuriš, A. Thompson, H. Sanganee, D. Dixon   +4 more
semanticscholar   +1 more source

Using EGA-GC to Analyze Nicotine N-oxide in Order to Explain Low Nicotine Concentrations in E-cigarette Liquids [PDF]

, 2018
Evolved-gas analysis coupled with gas chromatography (EGA-GC) was used to analyze e-cigarette liquids. Previous analyses of e-cigarette liquids have shown that the determined concentration of nicotine is lower than the advertised concentration.
Wuerch, Cory
core   +1 more source

Facile, Regio- and Diastereoselective Synthesis of Spiro-Pyrrolidine and Pyrrolizine Derivatives and Evaluation of Their Antiproliferative Activities

Molecules, 2014
A number of novel spiro-pyrrolidines/pyrrolizines derivatives were synthesized through [3+2]-cycloaddition of azomethine ylides with 3,5-bis[(E)-arylmethylidene]tetrahydro-4(1H)-pyridinones 2a–n. Azomethine ylides were generated in situ from the reaction
Abdulrahman I. Almansour, Raju Suresh Kumar, Farzana Beevi, Amir Nasrolahi Shirazi, H. Osman, R. Ismail, T. S. Choon, Brian Sullivan, Kellen McCaffrey, Alaa F. Nahhas, K. Parang, M. A. Ali   +11 more
semanticscholar   +1 more source

Design, synthesis and biological evaluation of 1,3-dihydroxyxanthone derivatives: Effective agents against acetylcholinesterase [PDF]

, 2017
The present work concerns the rational design and development of new inhibitors of acetylcholinesterase (AChE) based on the privileged xanthone scaffold.
Accordino, Sebastian Roberto, Appignanesi, Gustavo Adrian, Biscussi, Brunella, Gerbino, Darío César, Menéndez, Cintia Anabella, Murray, Ana Paula   +5 more
core   +1 more source

Enantioselective Total Synthesis of (—)-Acetylaranotin, a Dihydrooxepine Epidithiodiketopiperazine [PDF]

, 2012
The first total synthesis of the dihydrooxepine-containing epidithiodiketopiperazine (ETP) (−)-acetylaranotin (1) is reported. The key steps of the synthesis include an enantioselective azomethine ylide (1,3)-dipolar cycloaddition reaction to set the ...
Codelli, Julian A., Puchlopek, Angela L. A., Reisman, Sarah E.   +2 more
core   +1 more source

Crystal structure of ethyl 2′′,3-dioxo-7′,7a'-dihydro-1′H,3H,3′H-dispiro[benzo[b]thiophene-2,6′-pyrrolo[1,2-c]thiazole-5′,3′′-indoline]-7′-carboxylate

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C23H20N2O4S2, the central pyrrolidine ring adopts an envelope conformation with the spiro C atom, shared with the benzothiophene ring system, as the flap.
M. P. Savithri, M. Suresh, R. Raghunathan, R. Raja, A. SubbiahPandi   +4 more
doaj   +1 more source

β‐Quaternary α‐Amino Acids via Iridium‐Catalyzed Branched and Enantioselective Hydroalkylation of 1,1‐Disubstituted Styrenes

Angewandte Chemie International Edition, Accepted Article.
A cationic Ir(I)‐complex modified with the chiral diphosphine DM‐SEGPHOS mediates the hydroalkylation of diverse α‐methyl styrenes with N‐aryl glycine derivatives. The processes occur with complete branched selectivity and high enantioselectivity. Styrenes possessing higher α‐alkyl substituents also participate to provide the targets with moderate to ...
Fenglin Hong, L. Anders Hammarback, Yihong Wang, Craig M. Robertson, John Bower   +4 more
wiley   +1 more source