Design, synthesis, conformational analysis and nucleic acid hybridisation properties of thymidyl pyrrolidine-amide oligonucleotide mimics (POM) [PDF]
, 2003 Pyrrolidine-amide oligonucleotide mimics (POM) 1 were designed to be stereochemically and conformationally similar to natural nucleic acids, but with an oppositely charged, cationic backbone.
Cooper, M.A. +5 more
core +1 more source
Azaporphyrinoid‐Based Photo‐ and Electroactive Architectures for Advanced Functional Materials
Advanced Materials, EarlyView.A long‐standing collaboration between the Torres and Guldi groups has yielded diverse azaporphyrinoid‐based donor‐acceptor nanohybrids with promising applications in solar energy conversion. This conspectus highlights key molecular platforms and structure‐function relationships that govern light and charge management, supporting the rational design of ...
Jorge Labella +3 more
wiley +1 more source
Crystal structure of 4-methoxy-N-(piperidine-1-carbonothioyl)benzamide
Acta Crystallographica Section E: Crystallographic Communications, 2017 In the title compound, C14H18N2O2S, the piperidine ring has a chair conformation. Its mean plane is twisted with respect to the 4-methoxybenzoyl ring, with a dihedral angle of 63.0 (3)°.
Khairi Suhud +4 more
doaj +1 more source
How cinchona alkaloid-derived primary amines control asymmetric electrophilic fluorination of cyclic ketones. [PDF]
, 2014 The origin of selectivity in the α-fluorination of cyclic ketones catalyzed by cinchona alkaloid-derived primary amines is determined with density functional calculations.
Houk, KN, Lam, Yu-hong
core +2 more sources
Synthesis of a New Chiral Pyrrolidine [PDF]
Molecules, 2010 The synthesis of a new chiral pyrrolidine has been performed using 2,3-O-isopropylidene-D-erythronolactol as a suitable starting material.
Mari Fe. Flores +7 more
openaire +3 more sources
Advanced Synthesis &Catalysis, EarlyView.A novel methodology for the construction of aromatic and heteroaromatic trifluoropropynyl derivatives has been developed. The new protocol is based on a tandem Sonogashira cross‐coupling reaction between a bench‐stable trifluoropropynyl carbinol reagent, generated from the commercially available and inexpensive hydrofluoroolefin‐1234yf gas, and (hetero)
Emma Bodnár +3 more
wiley +1 more source
Design, synthesis and biological evaluation of 1,3-dihydroxyxanthone derivatives: Effective agents against acetylcholinesterase [PDF]
, 2017 The present work concerns the rational design and development of new inhibitors of acetylcholinesterase (AChE) based on the privileged xanthone scaffold.
Accordino, Sebastian Roberto +5 more
core +1 more source
Advanced Science, EarlyView.A key challenge in nicotine electroanalysis is the unresolved complexity of its interface process, which directly determines sensor metrics. Herein, the proton‐coupled electron transfer mechanism of nicotine is decoded for multi‐scenario portable electrochemical sensing.
Yi Peng +9 more
wiley +1 more source
Sonogashira/N-acyliminium ion aromatic π-cyclisation processes: access to tetra- and pentacyclic lactams [PDF]
, 2008 Application of the Sonogashira reaction of N-alkynylimides with 2-iodophenol or 2-iodo-N-tosylaniline affords 2-(N-alkylimino)-benzofurans and indoles in good yield.
Grigg, R., Sridharan, V., Sykes, D.A.
core +1 more source
1-(3-Pyridyl)pyrrolidine-2,5-dione [PDF]
Acta Crystallographica Section E Structure Reports Online, 2009 In the title mol-ecule, C(9)H(8)N(2)O(2), the dihedral angle between the pyridine and the pyrrolidine rings is 64.58 (12)°. In the crystal structure, weak C-H⋯π-electron ring inter-actions stabilize the packing.
Luan-Fang Yang, Yi-Ming Liu, Hong-Bo Hou
openaire +3 more sources