Angewandte Chemie, EarlyView.Concise total syntheses of five leuconoxine alkaloids have been achieved using a pyrrole‐centered strategy, which features a newly developed palladium/norbornene‐catalyzed pyrrole double C─H functionalization method, a divergent late‐stage oxidative dearomatization tactic, and no use of protecting groups.
Xin Liu +5 more
wiley +2 more sources
Nickel-Catalyzed cascade Cyclization-Negishi coupling of redox active esters for the synthesis of pyrrolidines [PDF]
, 2022 We have developed a Ni-catalyzed cascade cyclization/Negishicoupling reaction for the formation of pyrrolidines and pyrrolidinones starting from N-protected allylamines and acrylamides which contain a redox active ester group. The reaction provides two
Buñuel Magdalena, María Elena +3 more
core +1 more source
Does the exception prove the rule? - A comparative study of supramolecular synthons in a series of lactam esters [PDF]
, 2019 In this paper a series of simple lactam esters and carboxylic acids is studied with respect to their overall conformation and hydrogen bonding patterns. In total, eight lactams featuring Nα-substitution have been synthesized.
Gruber, Tobias +2 more
core +2 more sources
Towards Reaction Control: cis-Diastereoselective Reductive Dehydroxylation of 5-Alkyl-4-Benzyloxy-5-Hydroxy-2-Pyrrolidinones [PDF]
, 2012 通讯作者地址: Huang, PQA chemo-, regio-, and stereoselectively controlled reaction is highly desirable, yet challenging in organic synthesis. Diversely substituted cis and trans isomers of 2-alkyl-3-pyrrolidinols, 5-alkyl-4-hydroxy-2-pyrrolidinones, beta ...
Jian-Liang Ye +6 more
core +1 more source
Synthesis of the Pyrrolidinone Core of KSM-2690 B
Organic Letters, 2007 [reaction: see text] The first synthesis of the pyrrolidinone core of the polyene beta-lactone antibiotic KSM-2690 B is described. An ammonia-free Birch reductive aldol reaction utilizing acetaldehyde is one of the key steps, together with a ruthenium-catalyzed alkene isomerization reaction.
Donohoe, T, Chiu, J, Thomas, R
openaire +3 more sources
I. INCORPORATION OF FUNCTIONALITY AT THE β-POSITION FOR THE ZINC-MEDIATED CHAIN EXTENSION REACTION II. FORMAL SYNTHESIS OF HELIOTRIDANE AND PSEUDOHELIOTRIDANE THROUGH A ZINC-MEDIATED CHAIN EXTENSION APPROACH [PDF]
, 2021 The zinc-mediated chain extension reaction has been previously developed to incorporate alkyl or aryl substituents at the β position of the chain-extended product.
Arnista, Nicholas Alexander
core +4 more sources
Graft Copolymer‐Stabilized Liquid Metal Nanoparticles for Lithium‐Ion Battery Self‐Healing Anodes
Advanced Functional Materials, EarlyView.This study presents a self‐healing liquid metal anode for lithium‐ion batteries, where graft copolymer‐stabilized eutectic gallium indium (EGaIn) nanoparticles enhance stability and rate performance. The fluorinated grafted copolymer forms ionic channels, preventing EGaIn aggregation and facilitating lithium‐ion migration.
Youngwoo Seo +12 more
wiley +1 more source
Synthesis and Biological Evaluation of Thieno[3,2-d]- pyrimidinones, Thieno[3,2-d]pyrimidines and Quinazolinones: Conformationally Restricted 17b-Hydroxysteroid Dehydrogenase Type 2 (17b-HSD2) Inhibitors [PDF]
, 2018 In this study, a series of conformationally restricted thieno[3,2-d]pyrimidinones, thieno[3,2-d]pyrimidines and quinazolinones was designed and synthesized with the goal of improving the biological activity as 17-hydroxysteroid dehydrogenase type 2 ...
Hartmann, Rolf W. +2 more
core +1 more source
Advanced Materials, EarlyView.Bioxolography, a novel volumetric 3D‐bioprinting technique, enables rapid and high‐resolution fabrication of >1 cm3 engineered living materials. A newly developed three‐component photoinitiator system significantly enhances the photoreactivity of gelatin methacryloyl‐based bioresins, allowing for precise xolographic bioprinting.
Alexis Wolfel +6 more
wiley +1 more source
Synthesis and Characterization of Polymeric Materials Derived From Multifunctional Alkyl a-Hydroxymethylacrylates [PDF]
, 2008 The research presented in this dissertation covers the investigation of new materials derived from alkyl a-hydroxymethylacrylates (RHMA). The first project exposed in Chapter II involves the synthesis, characterization of RHMA-based reactive surfactants ...
Morizur, Jean-Francois
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