Results 191 to 200 of about 296,841 (265)

Real-time in vivo quantification of human skeletal muscle metabolism during exercise using hyperpolarised [1-¹³C]pyruvate reveals training-dependent metabolic adaptation

Serres S, Torchi A, Mallinson J, Bawden S, McGing J, Lobo D, Cooper A, Glaser M, Twyman F, Awais R, Årstad E, Auer D, Gowland P, Greenhaff P, Morris P.   +14 more
europepmc   +1 more source

The inhibitory effect of hepatic cancer energy metabolism on immune checkpoint therapy: perspectives from single-cell multi-omics analysis. [PDF]

Front Immunol
Li X, Tang L, Cao J, Liu Y.
europepmc   +1 more source

A Case of Multiple Mitochondrial Dysfunctions Syndrome 1 and Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Multiple mitochondrial dysfunctions syndrome 1 (MMDS1, MIM #605711) due to NFU1 gene defects is an ultra‐rare autosomal recessive inborn error of metabolism associated with reduced function of NFU1 iron–sulfur cluster (ISC) scaffold protein.
Charles R. DiFalco, Aaron Williams, Claudia Soler‐Alfonso, Emily Waskow, Elizabeth Mizerik, Fernando Scaglia, Chaya N. Murali   +6 more
wiley   +1 more source

Physiological Interpretation of the Lactate to Pyruvate AUC Ratio for Hyperpolarized [1-¹³C]-Pyruvate Studies. [PDF]

Magn Reson Med
Boyce RT, Harlan CJ, Wang Q, Walker CM, Lai SY, Merritt ME, Bankson JA.   +6 more
europepmc   +1 more source

Plant Virus Immunotherapy for HPV‐Associated Oropharyngeal Squamous Cell Carcinoma

Advanced NanoBiomed Research, EarlyView.
Cowpea mosaic virus (CPMV) nanoparticles are safe and potent cancer immunotherapy candidates with strong immunomodulatory activity. CPMV activates innate immunity, which in turn drives adaptive immune responses and promotes durable, systemic antitumor effects.
Jessica Fernanda Affonso de Oliveira, Patrick Opdensteinen, Andrea Simms, Seongwon Jung, Giuliana P. Mognol, Hui Chen, Judith A. Varner, Nicole F. Steinmetz   +7 more
wiley   +1 more source

Alanine Rewires the Communication Pathways Established During the Allosteric Activation of Liver Pyruvate Kinase by Fructose Bisphosphate. [PDF]

J Chem Inf Model
Kumutima J, Yao XQ, Hamelberg D.
europepmc   +1 more source

Spatial Cell Death and Oxidative Stress Dynamics in Gas Plasma‐Treated Tumor Tissues

Advanced NanoBiomed Research, EarlyView.
Schematic representation of the four experimental models to study tissue penetration and oxidation. Four tissue models were used. Human pancreatic cancer cells were grown on the chorioallantois membrane of chicken embryos and gas plasma‐treated in ovo, murine colorectal tumor tissue was gas plasma‐exposed ex vivo, murine squamous cell carcinoma cells ...
Anke Schmidt, Shahrzad Rokhsary, Linus Hübner, Lea Miebach, Sander Bekeschus   +4 more
wiley   +1 more source

Lactate and Lactylation in Pulmonary Hypertension: Comprehensive Landscape and Future Perspectives. [PDF]

Int J Med Sci
Dai Q, Cai Y, Wang X, Li X, Zheng R, Cao X, Zhang C, Xu J, Yi J, Song L, Dai A.   +10 more
europepmc   +1 more source

Hyperpolarization of Pyridine 15N‐Oxide Molecular Probes Enabled by Parahydrogen

Angewandte Chemie, EarlyView.
Pyridine 15N‐oxides are introduced as motifs for hyperpolarization studies and biochemical applications are demonstrated. ABSTRACT Magnetic resonance (MR) is a powerful non‐invasive technique for probing structural, functional, and metabolic processes with high spatial and temporal resolution.
Ruhuai Mei, Lisa Maria Fries, Gonzalo Gabriel Rodriguez, Charlotte von Petersdorff‐Campen, Leander Konstantin May, Julius Frederik Matz, Sergey Korchak, Grysette Daher, Stefan Glöggler   +8 more
wiley   +1 more source

In vivo assessment of the recovery of myocardial pyruvate dehydrogenase activity following a ketogenic diet. [PDF]

Cardiovasc Res
Chen J, Erfani Z, Elnwasany A, Al Nemri S, Park J, Huynh MT, Zaidi M, Harrison CE, Wen X, Szweda LI, Park JM.   +10 more
europepmc   +1 more source