Results 91 to 100 of about 23,834 (239)
Neurobiology of Disease, 2013 Huntington's disease (HD) causes preferential loss of a subset of neurons in the brain although the huntingtin protein is expressed broadly in various neural cell types, including astrocytes.
William Lee +6 more
doaj
An electron microscopic study of pyruvate carboxylase.
Journal of Biological Chemistry, 1979 Pyruvate carboxylases, purified to homogeneity from sheep and chicken liver, have been examined in the electron microscope and found to have a splayed tetrahedral structure which, in some views, appears similar to that described for this enzyme isolated from yeast.
John C. Wallace +3 more
openaire +3 more sources
Mitochondria ATP Pro‐Ferroptosis by Adjusting the Conversion of PUFA to PUFA‐PLs
MedComm – Oncology, Volume 4, Issue 3, September 2025.Glutamine deprivation can promote PUFA oxidation and PTGS2 expression through the upregulation of intracellular ROS, but not ferroptosis. Because glutamine deficiency exhausts mitochondrial ATP, thereby hinders the conversion of PUFA into their active form of PUFA‐CoA needed for lipid synthesis.
Chaoyi Xia +3 more
wiley +1 more source
Pyruvate carboxylase in lactating rat and rabbit mammary gland [PDF]
, 1969 Bilquis Gul, R. Dils
openalex +1 more source
Mitochondria as Regulators of Nonapoptotic Cell Death in Cancer
MedComm, Volume 6, Issue 8, August 2025.Mitochondrial fission and fusion are key processes in maintaining cellular health. Fission is driven by proteins like, Fis‐1, which recruits DRP‐1, to facilitate the division of mitochondria. Fusion, however, is mediated by mitofusion 1(MFN1), mitofusion 2(MFN2), and optic atrophy 1 (OPA1), which work together to merge mitochondria, allowing functional
Saloni Malla +8 more
wiley +1 more source
Journal of Lipid Research, 1979 Glucagon and N,(6)O(2)-dibutyryl cyclic adenosine 3‘,5‘-cyclic monophosphate (Bt(2)cAMP) inhibit fatty acid synthesis from acetate by more than 90% and prevent citrate formation in chick hepatocytes metabolizing glucose.
S D Clarke, P A Watkins, M D Lane
doaj
Astrocyte in Neurological Disease: Pathogenesis and Therapy
MedComm, Volume 6, Issue 8, August 2025.This review provides comprehensive overview of astrocytes in neurological disorders. Astrocytes contribute to neurological disorders via A1/A2 polarization, inducing neuroinflammation, synaptic, and BBB dysfunction. Metabolic disturbances in glucose, lipid, and amino acid pathways leading to oxidative stress and mitochondrial damage.
Meihui Huang +4 more
wiley +1 more source
PROTEOMICS, Volume 25, Issue 15, Page 13-26, August 2025.ABSTRACT Pancreatic beta cells secrete insulin in response to rising glucose levels, a process known as glucose‐stimulated insulin secretion (GSIS). Here, we acquire proteomes of rat pancreatic INS‐1 832/13 beta cells that were short‐term stimulated with 11 different glucose concentrations from 0 to 20 mM, quantifying the response of 3703 proteins ...
Nina Stremmel +6 more
wiley +1 more source
Holocarboxylase Synthetase 1 Physically Interacts with Histone H3 in Arabidopsis
Scientifica, 2013 Biotin is a water-soluble vitamin required by all organisms, but only synthesized by plants and some bacterial and fungal species. As a cofactor, biotin is responsible for carbon dioxide transfer in all biotin-dependent carboxylases, including acetyl-CoA
Xi Chen +2 more
doaj +1 more source
The enzyme kinetics of branched‐chain fatty acid synthesis of metazoan fatty acid synthase
Protein Science, Volume 34, Issue 8, August 2025.Abstract Branched‐chain fatty acids (BCFAs) exhibit enhanced oxidative stability, lower melting points, and reduced viscosity compared to straight‐chain fatty acids (StCFAs), making them valuable for biological systems and industrial applications.
Christian Gusenda +4 more
wiley +1 more source