Results 91 to 100 of about 141,799 (322)

Industrial strategies to minimize glycerol formation in ethanol fermentation by conventional Saccharomyces cerevisiae

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Industrial ethanol production faces the challenge of balancing metabolic efficiency with the minimization of byproducts such as glycerol, whose formation is intensified by osmotic, thermal, oxidative, and nutritional stresses. In the literature, two main approaches stand out for modulating its synthesis: the use of genetically modified strains
Lorena M. F. Leite, Silvio R. Andrietta, Telma T. Franco   +2 more
wiley   +1 more source

Cloning and expression of the Propionibacterium shermanii methylmalonyl-CoA epimerase gene in Escherichia coli : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]

, 1994
Genomic DNA was isolated from Propionibacterium shermanii (52W). A 454 bp DNA fragment coding for the methylmalonyl-CoA epimerase (EC 5.1.99.1, subsequently referred to as epimerase) was amplified from genomic DNA by the polymerase chain reaction using ...
Saafi, 'Etuate Lui
core  

Metabolic characterisation of E. coli citrate synthase and phosphoenolpyruvate carboxylase mutants in aerobic cultures [PDF]

, 2006
E. coli is still one of the most commonly used hosts for protein production. However, when it is grown with excess glucose, acetate accumulation occurs.
De Maeseneire, Sofie, De Mey, Marjan, Vandamme, Erick, Vandedrinck, Sofie   +3 more
core   +1 more source

Long Noncoding RNA GCASPC, a Target of miR-17-3p, Negatively Regulates Pyruvate Carboxylase-Dependent Cell Proliferation in Gallbladder Cancer.

Cancer Research, 2016
Long noncoding RNAs (lncRNA) are being implicated in the development of many cancers. Here, we report the discovery of a critical role for the lncRNA GCASPC in determining the progression of gallbladder cancer.
M. Ma, Yan Zhang, M. Weng, Shouhua Wang, Ye Hu, Z. Hou, Yiyu Qin, W. Gong, Yong-jie Zhang, X. Kong, Jian-dong Wang, Z. Quan   +11 more
semanticscholar   +1 more source

Biological Conversion of Formate to Organic Compounds: Toward a Sustainable Formate Bioeconomy

Carbon Energy, EarlyView.
Formate bioconversion plays a crucial role in achieving renewable resource utilization and sustainable development. To tap its full potential, it is important to identify the most appropriate microbial hosts for incorporating formate into building blocks, design the most promising metabolic pathways for transmitting formate into central carbon ...
Jinyi Qian, Tiantian Chai, Chunlei Zhao, Xiulai Chen   +3 more
wiley   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

piR-hsa-211106 Inhibits the Progression of Lung Adenocarcinoma Through Pyruvate Carboxylase and Enhances Chemotherapy Sensitivity [PDF]

, 2021
Yongmei Liu, Yanhan Dong, Xinjia He, Anjing Gong, Jinning Gao, Xiaodan Hao, Shuai Wang, Yuqiao Fan, Zibo Wang, Meng Li, Wenhua Xu   +10 more
openalex   +1 more source

Exclusive neuronal expression of SUCLA2 in the human brain [PDF]

, 2013
SUCLA2 encodes the ATP-forming subunit (A-SUCL-) of succinyl-CoA ligase, an enzyme of the citric acid cycle. Mutations in SUCLA2 lead to a mitochondrial disorder manifesting as encephalomyopathy with dystonia, deafness and lesions in the basal ganglia ...
A Kowluru, A Minelli, A Navarro-Sastre, A Rotig, A Vozza, AA Gerencser, AC Yu, Aniko Gál, Arpád Dobolyi, Attila G. Bagó, B Przybyla-Zawislak, C Chinopoulos, C Chinopoulos, C Chinopoulos, C Chinopoulos, C Chinopoulos, C Miller, Christos Chinopoulos, DO Lambeth, E Brekke, E Ostergaard, E Ostergaard, E Ostergaard, E Ostergaard, E Pfaff, EE McKee, EE McKee, EF Kadrmas, Elsebet Ostergaard, F Conti, F Conti, G Kiss, JC Wallace, JD Johnson, JH Ottaway, L Milon, M Lopes-Cardozo, M Palkovits, M Thomson, Miklós Palkovits, ML Pall, Mária J. Molnár, N Westergaard, O Elpeleg, R Carrozzo, R Dringen, RF Labbe, RL Strausberg, RP Shank, S Tanner, Tamás Dóczi, TM Jenkins, U Sonnewald, Vera Adam-Vizi, X Li, Z Zhang   +55 more
core   +2 more sources

Modulating Lysine Crotonylation in Ulcerative Colitis Maintains Mitochondrial Homeostasis

Exploration, EarlyView.
NaCr promotes KCr to impede the inflammatory progression of ulcerative colitis. KCr induces mitophagy by activating the PINK1/PARKIN pathway to restrict NLRP3 inflammasome activation, thereby decreasing the production and release of various inflammatory cytokines, such as IL‐1β and TNF‐α. KCr induces mitophagy and inhibits NLRP3 inflammasome activation
Tongtong Liu, Binyan Lin, Ying Zhang, Jiayu Su, Xiaochao Hu, Xuan Wang, E‐Hu Liu, Shijia Liu   +7 more
wiley   +1 more source

Photorespiration: metabolic pathways and their role in stress protection [PDF]

, 2000
Photorespiration results from the oxygenase reaction catalysed by ribulose-1,5-bisphosphate carboxylase/ oxygenase. In this reaction glycollate-2-phosphate is produced and subsequently metabolized in the photorespiratory pathway to form the Calvin ...
Anderson L. E., Astrid Wingler, C. B. Osmond, C. H. Foyer, Downton W. J. S., G. Bock, Kacser H., Koch K. E., Nakamura Y., Noctor G., Noctor G., Nour J. M., Nour J. M., Osmond C. B., Peter J. Lea, Richard C. Leegood, Richardson K. E., Ruban A.V., Tolbert N. E., W. Paul Quick, Walker R. R., Wingler A.   +21 more
core   +2 more sources