Results 31 to 40 of about 1,570 (117)

Diurnal Changes in Photosynthesis in Sugarcane Leaves: I. Carbon dioxide exchange rate, photosynthetic enzyme activities and metabolite levels relating to the C4 pathway and the Calvin cycle

Plant Production Science, 2000
Diurnal changes in carbon dioxide exchange rate (CER), stomatal conductance (gs), photosynthetic enzyme activities and metabolite levels relating to the C4 pathway and the Calvin cycle in sugarcane (Saccharum sp. cv.
Yu-Chun Du, Akihiro Nose, Ayumu Kondo, Kikuo Wasano   +3 more
doaj   +1 more source

Genome‐Wide CRISPR/Cas9 Library Screening Revealed Dietary Restriction of Glutamine in Combination with Inhibition of Pyruvate Metabolism as Effective Liver Cancer Treatment

Advanced Science, 2022
Hepatocellular carcinoma (HCC) is the second most lethal cancer worldwide. Glutamine is an essential, extracellular nutrient which supports HCC growth. Dietary glutamine deficiency may be a potential therapeutic approach for HCC.
Chunxue Yang, Derek Lee, Misty Shuo Zhang, Aki Pui‐Wah Tse, Lai Wei, Macus Hao‐Ran Bao, Bowie Po‐Yee Wong, Cerise Yuen‐Ki Chan, Vincent Wai‐Hin Yuen, Yiling Chen, Carmen Chak‐Lui Wong   +10 more
doaj   +1 more source

Effect of pyruvate kinase gene deletion on the physiology of Corynebacterium glutamicum ATCC13032 under biotin-sufficient non-glutamate-producing conditions: Enhanced biomass production

Metabolic Engineering Communications, 2015
The effect of pyruvate kinase gene (pyk) deletion on the physiology of Corynebacterium glutamicum ATCC13032 was investigated under biotin-sufficient, non-glutamate-producing conditions.
Kazunori Sawada, Masaru Wada, Takuya Hagiwara, Susumu Zen-in, Keita Imai, Atsushi Yokota   +5 more
doaj  

Characterization of the metabolic shift between oxidative and fermentative growth in Saccharomyces cerevisiae by comparative ¹³C flux analysis

Microbial Cell Factories, 2005
Background One of the most fascinating properties of the biotechnologically important organism Saccharomyces cerevisiae is its ability to perform simultaneous respiration and fermentation at high growth rate even under fully aerobic conditions.
Wittmann Christoph, Frick Oliver
doaj   +1 more source

Metabolic responses to pyruvate kinase deletion in lysine producing Corynebacterium glutamicum

Microbial Cell Factories, 2008
Background Pyruvate kinase is an important element in flux control of the intermediate metabolism. It catalyzes the irreversible conversion of phosphoenolpyruvate into pyruvate and is under allosteric control.
Wittmann Christoph, Klopprogge Corinna, Becker Judith   +2 more
doaj   +1 more source

Generation of an induced pluripotent stem cell line (SHCDNi007-A) from a patient with pyruvate carboxylase deficiency carrying compound heterozygous (c.182 T > C/ c.2581G > A) variants in PC

Stem Cell Research, 2023
Pyruvate carboxylase (PC) deficiency (PCD), due to biallelic PC variants, is a rare inherited metabolic disease, which is characterized by seizures, global developmental delay, as well as lactic acidosis, and elevated plasma pyruvate and alanine levels ...
Jingjing Sun, Pei Lu, Yunlin Shen, Li Ma
doaj  

Targeting Pyruvate Carboxylase by a Small Molecule Suppresses Breast Cancer Progression

Advanced Science, 2020
Rapid metabolism differentiates cancer cells from normal cells and relies on anaplerotic pathways. However, the mechanisms of anaplerosis‐associated enzymes are rarely understood.
Qingxiang Lin, Yuan He, Xue Wang, Yong Zhang, Meichun Hu, Weikai Guo, Yundong He, Tao Zhang, Li Lai, Zhenliang Sun, Zhengfang Yi, Mingyao Liu, Yihua Chen   +12 more
doaj   +1 more source

Breast Cancer-Derived Lung Metastases Show Increased Pyruvate Carboxylase-Dependent Anaplerosis

Cell Reports, 2016
Cellular proliferation depends on refilling the tricarboxylic acid (TCA) cycle to support biomass production (anaplerosis). The two major anaplerotic pathways in cells are pyruvate conversion to oxaloacetate via pyruvate carboxylase (PC) and glutamine ...
Stefan Christen, Doriane Lorendeau, Roberta Schmieder, Dorien Broekaert, Kristine Metzger, Koen Veys, Ilaria Elia, Joerg Martin Buescher, Martin Franz Orth, Shawn Michael Davidson, Thomas Georg Philipp Grünewald, Katrien De Bock, Sarah-Maria Fendt   +12 more
doaj   +1 more source

Ketogenic Diet: An Early Option for Epilepsy Treatment, Instead of A Last Choice Only

Biomedical Journal, 2012
Ketogenic diet (KD) was usually tried as a last resort in the treatment of intractable epilepsy after failure of many antiepileptics and even epilepsy surgery. Glucose transporter-1 deficiency and pyruvate dehydrogenase deficiency must be treated with KD
Huei-Shyong Wang, Kuang-Lin Lin
doaj   +1 more source

Pyruvate carboxylase in lactating rat and rabbit mammary gland [PDF]

, 1968
Bilquis Gul, R. Dils
openalex   +2 more sources