Results 181 to 190 of about 128,438 (311)
Beyond Histones: Unveiling the Functional Roles of Protein Acetylation in Prokaryotes and Eukaryotes
ABSTRACT Lysine acetylation plays a crucial role in cellular processes and is found across various evolutionary organisms. Recent advancements in proteomic techniques revealed the presence of acetylation in thousands of non‐histone proteins. Here, we conducted extensive meta‐analysis of 48 acetylomes spanning diverse organisms, including archaea ...
Bruno Sousa Bonifácio+6 more
wiley +1 more source
Role of pyruvate kinase M2 in regulating sepsis (Review). [PDF]
Hu Y+7 more
europepmc +1 more source
Manganese Neurotoxicity and Familial Disorders of Manganese Transport
ABSTRACT Manganese is the 12th most common element in the Earth's crust and is an essential industrial component. Biologically, this metal plays an important role as a constituent of numerous enzymes. While manganese is required for normal biochemical and physiological processes, manganese excess can lead to significant toxicity, particularly to the ...
Sidney M. Gospe Jr.
wiley +1 more source
Metabolomic analysis of Drosophila melanogaster larvae lacking pyruvate kinase. [PDF]
Heidarian Y+8 more
europepmc +1 more source
Muscle Pyruvate Kinase: Interaction with Substrates and Analogues Studied by Difference Spectroscopy [PDF]
Annie Brevet+3 more
openalex +1 more source
Sequeira et al. reveal how the glucagon‐like peptide‐1 receptor agonist (GLP‐1‐RA) semaglutide restores cardiomyocyte function in rats subjected to a high‐fat/high‐fructose diet (HFD). Employing fluorescence‐ and patch‐clamp technology in isolated cardiac myocytes, they demonstrate that semaglutide reverses HFD‐induced activation of L‐type calcium ...
Vasco Sequeira+12 more
wiley +1 more source
Improving clinical translation of mitoprotective therapies. 31P MRI, phosphorus‐31 magnetic resonance imaging; hiPSC‐CM, human‐induced pluripotent stem cell‐derived cardiomyocyte; IHD, ischaemic heart disease. Abstract Acute myocardial infarction (MI) remains a major cause of death and disability worldwide.
Melanie Paillard+29 more
wiley +1 more source
Pyruvate Kinase Function Correlates With Red Blood Cell Properties and Clinical Manifestations in Sickle Cell Disease. [PDF]
Traets MJM+17 more
europepmc +1 more source
Phosphocreatine does not inhibit rabbit muscle phosphofructokinase or pyruvate kinase.
Coy D. Fitch, Rekha Chevli, Max Jellinek
openalex +1 more source