Results 181 to 190 of about 128,438 (311)

Beyond Histones: Unveiling the Functional Roles of Protein Acetylation in Prokaryotes and Eukaryotes

open access: yesCell Biology International, EarlyView.
ABSTRACT Lysine acetylation plays a crucial role in cellular processes and is found across various evolutionary organisms. Recent advancements in proteomic techniques revealed the presence of acetylation in thousands of non‐histone proteins. Here, we conducted extensive meta‐analysis of 48 acetylomes spanning diverse organisms, including archaea ...
Bruno Sousa Bonifácio   +6 more
wiley   +1 more source

Bovine Pyruvate Kinases

open access: hybrid, 1973
Janet M. Cardenas   +2 more
openalex   +2 more sources

Role of pyruvate kinase M2 in regulating sepsis (Review). [PDF]

open access: yesMol Med Rep
Hu Y   +7 more
europepmc   +1 more source

Manganese Neurotoxicity and Familial Disorders of Manganese Transport

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Manganese is the 12th most common element in the Earth's crust and is an essential industrial component. Biologically, this metal plays an important role as a constituent of numerous enzymes. While manganese is required for normal biochemical and physiological processes, manganese excess can lead to significant toxicity, particularly to the ...
Sidney M. Gospe Jr.
wiley   +1 more source

Metabolomic analysis of Drosophila melanogaster larvae lacking pyruvate kinase. [PDF]

open access: yesG3 (Bethesda), 2023
Heidarian Y   +8 more
europepmc   +1 more source

Muscle Pyruvate Kinase: Interaction with Substrates and Analogues Studied by Difference Spectroscopy [PDF]

open access: bronze, 1975
Annie Brevet   +3 more
openalex   +1 more source

Semaglutide normalizes increased cardiomyocyte calcium transients in a rat model of high fat diet‐induced obesity

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1386-1397, April 2025.
Sequeira et al. reveal how the glucagon‐like peptide‐1 receptor agonist (GLP‐1‐RA) semaglutide restores cardiomyocyte function in rats subjected to a high‐fat/high‐fructose diet (HFD). Employing fluorescence‐ and patch‐clamp technology in isolated cardiac myocytes, they demonstrate that semaglutide reverses HFD‐induced activation of L‐type calcium ...
Vasco Sequeira   +12 more
wiley   +1 more source

Mitochondrial targets in ischaemic heart disease and heart failure, and their potential for a more efficient clinical translation. A scientific statement of the ESC Working Group on Cellular Biology of the Heart and the ESC Working Group on Myocardial Function

open access: yesEuropean Journal of Heart Failure, EarlyView.
Improving clinical translation of mitoprotective therapies. 31P MRI, phosphorus‐31 magnetic resonance imaging; hiPSC‐CM, human‐induced pluripotent stem cell‐derived cardiomyocyte; IHD, ischaemic heart disease. Abstract Acute myocardial infarction (MI) remains a major cause of death and disability worldwide.
Melanie Paillard   +29 more
wiley   +1 more source

Pyruvate Kinase Function Correlates With Red Blood Cell Properties and Clinical Manifestations in Sickle Cell Disease. [PDF]

open access: yesAm J Hematol
Traets MJM   +17 more
europepmc   +1 more source

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