Results 181 to 190 of about 216,078 (374)

In vivo toxic and lethal cardiorespiratory effects of a synthetic quaternary ammonium salt derivative of haloperidol in mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Hematoxylin–eosin (H&E) stains of the heart, liver, lung, and kidney show acute toxicity. Abstract Background To investigate the toxicity of N‐n‐butyl haloperidol iodide (F2), a quaternary ammonium salt derivative of haloperidol, in mice for potential therapeutic purposes. Methods The acute median lethal dose (LD50) of F2 was determined using the Bliss
Jilin Liao   +6 more
wiley   +1 more source

Effects of pyruvate administration on infarct volume and neurological deficits following permanent focal cerebral ischemia in rats [PDF]

open access: yes, 2003
Recent experimental evidences indicate that pyruvate, the final metabolite of glycolysis, has a remarkable protective effect against different types of brain injury.
Candelario-Jalil, Eduardo   +3 more
core  

Yeast Pyruvate Kinase

open access: hybrid, 1969
James R. Hunsley, Clarence H. Suelter
openalex   +2 more sources

“Hydroxylamine Kinase” and Pyruvic Kinase

open access: yesJournal of Biological Chemistry, 1960
Floyd P. Kupiecki, Minor J. Coon
openaire   +3 more sources

Sugar‐sensing swodkoreceptors and swodkocrine signaling

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Sugar‐sensing swodkoreceptors that trigger swodkocrine signaling. Abstract Sugars are one of the major metabolites and are essential for nucleic acid synthesis and energy production. In addition, sugars can act as signaling molecules. To study sugar signaling at the systemic level, there is an urgent need to systematically identify sugar‐sensing ...
Savani Anbalagan
wiley   +1 more source

CLINICAL PATHOPHYSIOLOGY OF PYRUVATE KINASE DEFICIENCY

open access: yesMedicina v Kuzbasse
In our review we discuss pyruvate kinase deficiency, which is the most prevalent hereditary hemolytic enzymopathy resulting from a glycolytic defect.
Павел Павлович Поляков   +2 more
doaj  

An Update: Enzymatic Synthesis for Industrial Applications

open access: yesAngewandte Chemie International Edition, Accepted Article.
Supported by rapid technological advancements, biocatalytic applications have matured into a sustainable, scalable, and cost‐competitive alternatives to established chemical catalysis. This review presents the most recent examples of enzyme‐based solutions for the manufacturing of molecules with extended carbon‐carbon frameworks and multiple ...
Thomas Bayer   +4 more
wiley   +1 more source

Hepatic gluconeogenesis and regulatory mechanisms in lactating ruminants: A literature review

open access: yesAnimal Research and One Health, EarlyView.
phosphoenolpyruvate carboxy kinase, FBP1, and glucose‐6‐phosphatase are key rate‐limiting enzymes that determine the efficiency of gluconeogenesis. The main substrate for gluconeogenesis in the liver of ruminants is propionate, which provides more than 60% of the carbon source for gluconeogenesis.
Guoyan Wang   +5 more
wiley   +1 more source

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