Aerobic Glycolysis in the Retina: Functional Roles of Pyruvate Kinase Isoforms
Frontiers in Cell and Developmental Biology, 2020 One hundred years ago, Otto Heinrich Warburg observed that postmitotic retinal cells are the highest oxygen-consuming cells in the body. He compared these cells to actively growing mitotic tumor cells since both cells reprogram glucose for anabolic ...
R. V. Rajala
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Minimizing acetate formation in E. coli fermentations [PDF]
, 2007 Escherichia coli remains the best established production organisms in industrial biotechnology. However, during aerobic fermentation runs at high growth rates, considerable amounts of acetate are accumulated as by-product.
De Maeseneire, Sofie +3 more
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Programming Skeletal Muscle Metabolic Flexibility in Offspring of Male Rats in Response to Maternal Consumption of Slow Digesting Carbohydrates during Pregnancy [PDF]
, 2020 Skeletal muscle plays a relevant role in metabolic flexibility and fuel usage and the associated muscle metabolic inflexibility due to high-fat diets contributing to obesity and type 2 diabetes.
Andújar, Eloísa +7 more
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The contribution of two isozymes to the pyruvate kinase activity of Vibrio cholerae: One K+-dependent constitutively active and another K+-independent with essential allosteric activation. [PDF]
PLoS ONE, 2017 In a previous phylogenetic study of the family of pyruvate kinase EC (2.7.1.40), a cluster with Glu117 and another with Lys117 were found (numbered according to the rabbit muscle enzyme).
Carlos Guerrero-Mendiola +4 more
doaj +1 more source
Pyruvate Kinase Revisited [PDF]
Journal of Biological Chemistry, 2005 Desde hace más de 50 años, se sabe que el K+ es un activador esencial de la piruvato quinasa (Kachmar, J. F., y Boyer, P. D. (1953) J. Biol. Chem. 200, 669-683). Sin embargo, el papel de K+ en la catálisis por piruvato quinasa no se ha entendido completamente.
Jesús Oria‐Hernández +3 more
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Prevalence of pyruvate kinase deficiency: A systematic literature review
European Journal of Haematology, 2020 Pyruvate kinase deficiency (PK deficiency) is a rare disorder caused by compound heterozygosity or homozygosity for > 300 mutations in the PKLR gene. To understand PK deficiency prevalence, we conducted a systematic literature review.
M. Secrest +6 more
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Phosphoenolpyruvate Carboxykinase Is Involved in the Decarboxylation of Aspartate in the Bundle Sheath of Maize [PDF]
, 1999 We recently showed that maize (Zea mays L.) leaves contain appreciable amounts of phosphoenolpyruvate carboxykinase (PEPCK; R.P. Walker, R.M. Acheson, L.I. Técsi, R.C. Leegood [1997] Aust J Plant Physiol 24: 459–468).
Chen, Z. +3 more
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Proteomic study of the membrane components of signalling cascades of Botrytis cinerea controlled by phosphorylation [PDF]
, 2019 Protein phosphorylation and membrane proteins play an important role in the infection of plants by phytopathogenic fungi, given their involvement in signal transduction cascades.
Amil, Francisco +9 more
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Specificity of pyruvate kinase [PDF]
Biochimica et Biophysica Acta, 1959 Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/32459/1/0000543 ...
openaire +4 more sources
A genetic toolkit for the analysis of metabolic changes in Drosophila provides new insights into metabolic responses to stress and malignant transformation [PDF]
, 2019 Regulation of the energetic metabolism occurs fundamentally at the cellular level, so analytical strategies must aim to attain single cell resolution to fully embrace its inherent complexity.
Behrensen, C. +3 more
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