Results 41 to 50 of about 234,539 (335)

ROLE OF HOST CELL GLYCOLYTIC PROTEINS; ALPHA ENOLASE AND PYRUVATE KINASE IN INFLUENZA A VIRUS INFECTED CELLS

open access: yesInternational Journal of Infectious Diseases, 2023
Intro: Influenza A virus, a respiratory pathogen known to manipulate various cellular metabolic processes including glycolysis. Our earlier studies demonstrated the interaction of influenza A viral structural proteins; nucleoprotein and matrix protein ...
P. Goyal, M.S. Rajala
doaj   +1 more source

Role of AMPK Throughout Meiotic Maturation in the Mouse Oocyte: Evidence for Promotion of Polar Body Formation and Suppression of Premature Activation [PDF]

open access: yes, 2010
This study was conducted to assess the role of AMPK in regulating meiosis in mouse oocytes from the germinal vesicle stage to metaphase II. Exposure of mouse cumulus cell-enclosed oocytes (CEO) and denuded oocytes (DO) during spontaneous maturation in ...
Davis, Christopher C.   +2 more
core   +2 more sources

Effects of Pyruvate Kinase Phosphorylation and Acetylation on Its Activity and Structure

open access: yesShipin gongye ke-ji
Pyruvate kinase is one of the important glycolytic enzymes that affects the rate of postmortem muscle glycolysis and then regulates meat quality.
Xiaolan HUANG   +7 more
doaj   +1 more source

Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production

open access: yesCell Reports, 2019
Summary: Pyruvate kinase is an important enzyme in glycolysis and a key metabolic control point. We recently observed a pyruvate kinase liver isoform (PKL) phosphorylation site at S113 that correlates with insulin resistance in rats on a 3 day high-fat ...
Brandon M. Gassaway   +18 more
doaj   +1 more source

Pyruvate kinase deficiency mimicking congenital dyserythropoietic anemia type I

open access: yesThe Turkish Journal of Pediatrics, 2022
Background. Pyruvate kinase (PK) deficiency is the most common enzyme abnormality in the glycolytic pathway. Here, we describe two siblings with PK deficiency that mimicked congenital dyserythropoietic anemia (CDA) type I. Case.
Ayça Koca Yozgat   +4 more
doaj   +1 more source

Probing Conformational Feature of a Recombinant Pyruvate Kinase by Limited Proteolysis [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 2013
Pyruvate kinase is a key enzyme in glycolytic pathway that catalyzes the transphosphorylation between phosphoenolpyruvate and ADP to yield ATP and Pyruvate.
M. Banijamali   +2 more
doaj  

Sheng-Mai San extracts attenuate heart injury in chronic intermittent hypoxia via suppressing oxidative damage and regulating glucose metabolism

open access: yesPharmacological Research - Modern Chinese Medicine, 2022
Background: Sheng-Mai San extracts (SMSE), derived from a Chinese medicine formula Sheng-Mai San, benefits prevention and treatment of cardiovascular disease.
Chunhua Liu   +6 more
doaj   +1 more source

LC-MS proteomics analysis of the iInsulin/IGF-1-deficient Caenorhabditis elegans daf-2(e1370) mutant reveals extensive restructuring of intermediary metabolism [PDF]

open access: yes, 2014
The insulin/IGF-1 receptor is a major known determinant of dauer formation, stress resistance, longevity, and metabolism in Caenorhabditis elegans. In the past, whole-genome transcript profiling was used extensively to study differential gene expression ...
Braeckman, Bart   +7 more
core   +2 more sources

Cardiosphere-derived cells demonstrate metabolic flexibility that Is influenced by adhesion status [PDF]

open access: yes, 2017
Adult stem cells demonstrate metabolic flexibility that is regulated by cell adhesion status. The authors demonstrate that adherent cells primarily utilize glycolysis, whereas suspended cells rely on oxidative phosphorylation for their ATP needs.
Abraham, M. Roselle   +13 more
core   +2 more sources

Pyruvate kinase deficiency and PKLR gene mutations: Insights from molecular dynamics simulation analysis

open access: yesHeliyon
Pyruvate kinase deficiency is a rare hereditary erythrocyte enzyme disease caused by mutations in the pyruvate kinase liver and red blood cell gene. The clinical presentations of pyruvate kinase deficiency are significantly heterogeneous, ranging from ...
Yang Wang   +13 more
doaj   +1 more source

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