Results 31 to 40 of about 23,522 (167)

G-quadruplexes: Kinetic stability and effects on the c-KIT promoter

, 2013
In addition to the famous Watson & Crick model for B-form duplex DNA, guanine-rich DNA sequences can self-assemble under certain conditions to form a four-stranded structure known as a G-quadruplex. G-quadruplexes are composed of stacks of Gquartets,
Raouf, Tara
core  

A pyrene-imidazolium derivative that selectively Recognizes G-Quadruplex DNA

, 2012
G-quadruplexes, formed of four stranded guanine bases stabilized by monovalent cations, serve important role in cancer cell growth and control gene expression in telomere. Since there are various types of quadruplex structures, rapid and simple screening
Kim, Ha Na, Yoon, Juyoung, DavidRSpring, Kim, Hee-Eun, Lee, Hee-Seung, Lee, Joon-Hwa, Xu, Zhaochao, WenjunWu, Lee, Eun-Hae   +8 more
core   +1 more source

Quadruplex-Interactive Agents as Telomerase Inhibitors:  Synthesis of Porphyrins and Structure−Activity Relationship for the Inhibition of Telomerase

, 2016
The cationic porphyrin 5,10,15,20-tetra-(N-methyl-4-pyridyl)porphyrin (TMPyP4) binds to quadruplex DNA and is thereby an inhibitor of human telomerase (Wheelhouse et al. J. Am. Chem. Soc. 1998, 120, 3261−3262).
Dong-Fang Shi (3012903), Richard T. Wheelhouse (1912465), Daekyu Sun (11744), Laurence H. Hurley (11747)   +3 more
core   +1 more source

Additional file 8: Table S6. of Recombination events among virulence genes in malaria parasites are associated with G-quadruplex-forming DNA motifs

, 2016
Putative G-quadruplex-forming sequences in the P. berghei ANKA genome (version 3). Genome searched using ‘QGRS Mapper’ [35] with the parameters G3 N(0–11) G3 N(0–11) G3 N(0–11) G3 [17].
Adam Stanton (3455450), Catherine Merrick (3455447), Gemma Graham (719041), Lynne Harris (3455453)   +3 more
core   +1 more source

Additional file 12 of Conserved associations between G-quadruplex-forming DNA motifs and virulence gene families in malaria parasites

, 2020
Additional file 12 Table S7. Putative G-quadruplex-forming sequences in the genomes of Plasmodium parasites, found by QGRS Mapper. Genomes were downloaded from PlasmoDB, v. 44, and searched using QGRS Mapper with the parameters: regex: G3N(0 − 11)G3N(0 − 
Hunter L. Gage (8592042), Catherine J. Merrick (8592045)   +1 more
core   +1 more source

DNA Damage Accelerates G‑Quadruplex Folding in a Duplex-G-Quadruplex-Duplex Context

Molecular details for the impact of DNA damage on folding of potential G-quadruplex sequences (PQSs) to noncanonical DNA structures involved in gene regulation are poorly understood.
Aaron M. Fleming (1314534), Brandon Leonel Guerra Castañaza Jenkins (18346284), Cynthia J. Burrows (1314543), Bethany A. Buck (2702977)   +3 more
core   +1 more source

Additional file 5: Table S4. of Recombination events among virulence genes in malaria parasites are associated with G-quadruplex-forming DNA motifs

, 2016
Putative G-quadruplex-forming sequences in the P. falciparum Dd2 genome. Genome searched using ‘QGRS Mapper’ [35] with the parameters G3 N(0–11) G3 N(0–11) G3 N(0–11) G3 [17].
Adam Stanton (3455450), Catherine Merrick (3455447), Gemma Graham (719041), Lynne Harris (3455453)   +3 more
core   +1 more source

Quadruplex DNA: structural features and potential applications

, 2008
Quadruplex DNA: structural features and potential ...
GALEONE, ALDO
core  

Spectroscopic Evidence of Human Telomeric G-quadruplex

, 2009
The structural interconversion between the G-quadruplex and duplex in vivo is an important subject because it is believed that the formation of G-quadruplex structure depends on the denaturation of the duplex [1].
冯兆池, 周俊, 李灿
core  

G-Quadruplexes (GQU) [PDF]

Journal of Nucleic Acids, 2018
Shozeb Haider, Gary N. Parkinson, Thomas C. Marsh   +2 more
openaire   +4 more sources