Results 71 to 80 of about 35,351 (202)

Synthesis of 1‐Alkynylboronates, 1,1‐Diborylalkenes, and 1,1,1‐Triborylalkanes: Challenges and Opportunities

Chemistry – A European Journal, EarlyView.
ABSTRACT In the field of organoboron chemistry, multi(boronate) esters have emerged as crucial intermediates, with various applications in synthetic chemistry, material technology, and life sciences. This mini‐review discusses recent advancement in the synthesis of these versatile compounds, particularly alkynylboronates, 1,1‐diborylalkenes, and 1,1,1 ...
Son Hoai Doan, Vu Nguyen Tran, Thanh Vinh Nguyen   +2 more
wiley   +1 more source

The quinoline framework and related scaffolds in natural products with anti-Leishmania properties

Frontiers in Chemistry
For almost one hundred years, the quinoline heterocycle has been recognized as a privileged pharmacophore in anti-Leishmania agents. Early on, the action of compounds with this scaffold, found in some natural alkaloids, was tested against different ...
Gloria Yaluff, Gloria Yaluff, Leídi Herrera, Leídi Herrera, Miriam Soledad Rolón, Celeste Vega, Hugo Cerecetto, Hugo Cerecetto   +7 more
doaj   +1 more source

Copper‐ and Silver‐Catalyzed Reactions of Active Methylene Isocyanides: Facile Access to Highly Substituted Five‐ and Six‐Membered Heterocycles

Chemistry – A European Journal, EarlyView.
This review summarizes recent advances in copper‐ and silver‐catalyzed reactions of active methylene isocyanides for the synthesis of highly substituted five‐ and six‐membered heterocycles. Emphasis is placed on [3+n] cycloadditions, annulations, and asymmetric strategies, highlighting current limitations and future opportunities in heterocycle ...
Jimil George, Kyungsoo Oh
wiley   +1 more source

Crystal structure of 3-bromomethyl-2-chloro-6-(dibromomethyl)quinoline

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C11H7Br3ClN, the quinoline ring system is approximately planar (r.m.s. = 0.011 Å). In the crystal, molecules are linked by C—H...Br interactions forming chains along [10-1].
Kasirajan Gayathri, Palathurai S. Mohan, Judith A. K. Howard, Hazel A. Sparkes   +3 more
doaj   +1 more source

Engineering Lipid Nanoparticles for Precision RNA Delivery: Design Principles, Targeting Strategies, and Clinical Prospects

Cancer Nexus, EarlyView.
ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han, Ying Wang, Xintao Gao, Yan Lei, Yantao Li, Zhiyong Tang   +5 more
wiley   +1 more source

Crystal structure of hexaaquanickel(II) bis{5-bromo-7-[(2-hydroxyethyl)amino]-1-methyl-6-oxidoquinolin-1-ium-3-sulfonate} monohydrate

Acta Crystallographica Section E: Crystallographic Communications, 2016
The asymmetric unit of the title compound, [Ni(H2O)6](C12H12BrN2O5S)2·H2O, contains a half hexaaquanickel(II) complex cation with the NiII ion lying on an inversion center, one 5-bromo-7-[(2-hydroxyethyl)amino]-1-methyl-6-oxidoquinolin-1-ium-3-sulfonate (
Hai Le Thi Hong, Vinh Nguyen Thi Ngoc, Anh Do Thi Van, Luc Van Meervelt   +3 more
doaj   +1 more source

Enhancement of the Plant‐Accessible Phosphate Fraction in Sewage Sludge Ashes by Na+ or K+ Addition Prior to Combustion

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
The addition of Na2CO3 or K2CO3 to sewage sludge prior to combustion leads to the production of ashes containing phosphate in the form of buchwaldite‐like phases (Ca(Na/K)PO4). Compared to conventional sewage sludge mono‐ashes, such Na‐ or K‐ashes show greatly increased P‐solubilities and proved to be potent P‐fertiliser materials in greenhouse ...
Lorenz Bier‐Schorr, Viktoria Gräser, Michael Scherer‐Lorenzen, Peter Hajek, Philipp Kurz   +4 more
wiley   +1 more source

Recent Advances in Metal-Free Quinoline Synthesis

Molecules, 2016
The quinoline ring system is one of the most ubiquitous heterocycles in the fields of medicinal and industrial chemistry, forming the scaffold for compounds of great significance.
Ginelle A. Ramann, Bryan J. Cowen
doaj   +1 more source

Remote Migratory Reductive Arylation of Unactivated Alkenes Enabled by Electrochemical Nickel Catalysis

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
we have developed an electrochemical Ni−H catalyzed arylation coupling method of unactivated alkenes with aryl halides. The method displays broad functional group tolerance and proceeds under very mild conditions. Furthermore, aryl chlorides were also compatible substrates in this catalytic system. This conversion holds significant implications for the
Chao Xu, Ru‐Han A, Xiao‐Feng Wu
wiley   +1 more source

8-Hydroxyquinoline Glycoconjugates: Modifications in the Linker Structure and Their Effect on the Cytotoxicity of the Obtained Compounds

Molecules, 2019
Small molecule nitrogen heterocycles are very important structures, widely used in the design of potential pharmaceuticals. Particularly, derivatives of 8-hydroxyquinoline (8-HQ) are successfully used to design promising anti-cancer agents. Conjugating 8-
Monika Krawczyk, Gabriela Pastuch-Gawołek, Aleksandra Pluta, Karol Erfurt, Adrian Domiński, Piotr Kurcok   +5 more
doaj   +1 more source