Results 1 to 10 of about 446 (164)

Hydrogen Storage: Thermodynamic Analysis of Alkyl-Quinolines and Alkyl-Pyridines as Potential Liquid Organic Hydrogen Carriers (LOHC)

Applied Sciences, 2021
The liquid organic hydrogen carriers (LOHC) are aromatic molecules, which can be considered as an attractive option for the storage and transport of hydrogen. A considerable amount of hydrogen up to 7–8% wt.
Sergey P. Verevkin, Sergey P. Safronov, Artemiy A. Samarov, Sergey V. Vostrikov   +3 more
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N-(Quinolin-8-yl)quinoline-2-carboxamide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2012
In the title compound, C19H13N3O, the dihedral angle between the two quinoline systems is 11.54 (3)°. The molecular conformation is stabilized by intramolecular N—H...N and C—H...O hydrogen bonds, with N—H...N being bifurcated towards the two N atoms of the two quinoline rings.
Yanfeng Li, Hongbo Zhou, Xiaoping Shen
openaire   +3 more sources

2-Arylquinolines as novel anticancer agents with dual EGFR/FAK kinase inhibitory activity: synthesis, biological evaluation, and molecular modelling insights

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
In this study, different assortments of 2-arylquinolines and 2,6-diarylquinolines have been developed. Recently, we have developed a new series of 6,7-dimethoxy-4-alkoxy-2-arylquinolines as Topoisomerase I (TOP1) inhibitors with potent anticancer ...
Mostafa M. Elbadawi, Wagdy M. Eldehna, Amer Ali Abd El-Hafeez, Warda R. Somaa, Amgad Albohy, Sara T. Al-Rashood, Keli K. Agama, Eslam B. Elkaeed, Pradipta Ghosh, Yves Pommier, Manabu Abe   +10 more
doaj   +1 more source

Chiral Phosphoric Acid Promoted Chiral 1H NMR Analysis of Atropisomeric Quinolines

Frontiers in Chemistry, 2021
An efficient enantioselective NMR analysis of atropisomeric quinolines in the promotion of chiral phosphoric acid is described, in which a variety of racemic 4-aryl quinolines were well-recognized with up to 0.17 ppm ΔΔδ value.
Junlin Wan, Jun Jiang, Juan Li
doaj   +1 more source

Synthesis, delivery, and molecular docking of fused quinolines as inhibitor of Hepatitis A virus 3C proteinase

Scientific Reports, 2021
It is widely accepted that Hepatitis A virus (HAV) is responsible for liver failure and even death in older people and in people with other serious health issues; so, proposing new compounds with inhibitory activity can help to treated of these disease’s.
Mehrnaz Rafiei Jorshari, Manouchehr Mamaghani, Parivash Jahanshahi   +2 more
doaj   +1 more source

Design, Synthesis and Antimicrobial Activities of Quinoline-Based FabZ Inhibitors as Promising Antimicrobial Drugs

Medical Sciences Forum, 2022
At present, antimicrobial resistance is one of the most significant public health challenges [...]
Laurie Bibens, Jean-Paul Becker, Nadine Lemaitre, François Peltier, Virginie Morel, Céline Damiani, Nicolas Taudon, Alexandra Dassonville-Klimpt, Pascal Sonnet   +8 more
doaj   +1 more source

Transition-metal-free approach to quinolines via direct oxidative cyclocondensation reaction of N,N-dimethyl enaminones with o-aminobenzyl alcohols

Frontiers in Chemistry, 2022
A transition-metal-free method for the construction of 3-substituted or 3,4-disubstituted quinolines from readily available N,N-dimethyl enaminones and o-aminobenzyl alcohols is reported.
Kairui Rao, Zhangmengjie Chai, Pan Zhou, Donghan Liu, Yulin Sun, Fuchao Yu   +5 more
doaj   +1 more source

Multi-Substituted Quinolines as HIV-1 Integrase Allosteric Inhibitors

Viruses, 2022
Allosteric HIV-1 integrase (IN) inhibitors, or ALLINIs, are a new class of antiviral agents that bind at the dimer interface of the IN, away from the enzymatic catalytic site and block viral replication by triggering an aberrant multimerization of the ...
Long Phi Dinh, Jian Sun, Courtney D. Glenn, Krunal Patel, Julie A. Pigza, Matthew G. Donahue, Larry Yet, Jacques J. Kessl   +7 more
doaj   +1 more source

Quinoline Functionalized Schiff Base Silver (I) Complexes: Interactions with Biomolecules and In Vitro Cytotoxicity, Antioxidant and Antimicrobial Activities

Molecules, 2021
A series of fifteen silver (I) quinoline complexes Q1–Q15 have been synthesized and studied for their biological activities. Q1–Q15 were synthesized from the reactions of quinolinyl Schiff base derivatives L1–L5 (obtained by condensing 2 ...
Adesola A. Adeleke, Sizwe J. Zamisa, Md. Shahidul Islam, Kolawole Olofinsan, Veronica F. Salau, Chunderika Mocktar, Bernard Omondi   +6 more
doaj   +1 more source

Iron-catalyzed indolo[2,3-c]quinoline synthesis from nitroarenes and benzylic alcohols/aldehydes promoted by elemental sulfur

Green Synthesis and Catalysis, 2022
An iron-catalyzed strategy for the rapid synthesis of indolo[2,3-c]quinolines has been developed. This cascade reaction involving alcohol oxidation, nitro reduction, and oxidative annulation was achieved in a one-pot.
Rong Li, Shuxin Jiang, Haolin Zheng, Hanwen Lei, Zhi Huang, Shanping Chen, Guo-Jun Deng   +6 more
doaj   +1 more source