Results 31 to 40 of about 49,482 (250)

Quinoline-8-sulfonamide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2012
In the title compound, C(9)H(8)N(2)O(2)S, the sulfamoyl NH(2) group is involved in intra-molecular N-H⋯N and inter-molecular N-H⋯O hydrogen bonding. In the crystal, molecules are linked via pairs of N-H⋯O hydrogen bonds, forming inversion dimers, which are further associated through π-π stacking inter-actions between the quinoline benzene rings ...
Marciniec, Krzysztof, Maślankiewicz, Andrzej, Nowak, Maria, Kusz, Joachim   +3 more
openaire   +2 more sources

Synthesis of Cyclic Amidines from Quinolines by a Borane-Catalyzed Dearomatization Strategy.

Organic Letters, 2020
Described herein is the development of a new synthetic route to cyclic amidines from quinolines. The borane-catalyzed 1,4-hydrosilylation of quinoline was utilized for the dearomatization of the quinolines.
V. Cao, Soungyun Mun, Seo Ha Kim, Gyeong Un Kim, Hyung Guk Kim, Seewon Joung   +5 more
semanticscholar   +1 more source

A Hybrid of Amodiaquine and Primaquine Linked by Gold(I) Is a Multistage Antimalarial Agent Targeting Heme Detoxification and Thiol Redox Homeostasis

Pharmaceutics, 2022
Hybrid-based drugs linked through a transition metal constitute an emerging concept for Plasmodium intervention. To advance the drug design concept and enhance the therapeutic potential of this class of drugs, we developed a novel hybrid composed of ...
Caroline De Souza Pereira, Helenita Costa Quadros, Samuel Yaw Aboagye, Diana Fontinha, Sarah D’Alessandro, Margaret Elizabeth Byrne, Mathieu Gendrot, Isabelle Fonta, Joel Mosnier, Diogo Rodrigo M. Moreira, Nicoletta Basilico, David L. Williams, Miguel Prudêncio, Bruno Pradines, Maribel Navarro   +14 more
doaj   +1 more source

Visible-light-driven radical Friedländer hetero-annulation of 2-aminoaryl ketone and α-methylene carbonyl compound via organic dye fluorescein through a single-electron transfer (SET) pathway

BMC Chemistry, 2022
The discoveries recommend that the photoinduced conditions of fluorescein-determined go about as impetus for photochemically combining polysubstituted quinolines in ethanol at room temperature under air environment by means of revolutionary Friedländer ...
Farzaneh Mohamadpour
doaj   +1 more source

Synthesis and Antimycobacterial Evaluation of N-(4-(Benzyloxy)benzyl)-4-aminoquinolines

Molecules, 2022
Tuberculosis remains a global health problem that affects millions of people around the world. Despite recent efforts in drug development, new alternatives are required.
Estevão Silveira Grams, Alessandro Silva Ramos, Mauro Neves Muniz, Raoní S. Rambo, Marcia Alberton Perelló, Nathalia Sperotto, Laura Calle González, Lovaine Silva Duarte, Luiza Galina, Adilio Silva Dadda, Guilherme Arraché Gonçalves, Cristiano Valim Bizarro, Luiz Augusto Basso, Pablo Machado   +13 more
doaj   +1 more source

Evolution of PIKK family kinase inhibitors: A new age cancer therapeutics

Frontiers in Bioscience-Landmark, 2020
Phosphatidylinositol-3 kinase-related kinases (PIKKs) belong to a family of atypical serine/threonine kinases in humans. They actively participate in a diverse set of cellular functions such as meiotic, V(D)J recombination, chromosome maintenance, DNA ...
Althaf Shaik, Sivapriya Kirubakaran
doaj   +1 more source

Quinoline-2-carbonitrile [PDF]

Acta Crystallographica Section E Structure Reports Online, 2010
In the title compound, C(10)H(6)N(2), the mol-ecule is almost planar, with an r.m.s. desviation of 0.014 Å. The dihedral angle between the aromatic rings is 1.28 (16)°. In the crystal, mol-ecules are stacked along the axis by way of weak aromatic π-π stacking inter-actions between the benzene and pyridine rings of adjacent mol-ecules [centroid-centroid
Wan-Sin Loh, Ching Kheng Quah, Madhukar Hemamalini, Hoong‐Kun Fun   +3 more
openaire   +3 more sources

Synthesis of SF5-containing benzisoxazoles, quinolines, and quinazolines by the Davis reaction of nitro-(pentafluorosulfanyl)benzenes

Beilstein Journal of Organic Chemistry, 2013
Meta- or para-nitro-(pentafluorosulfonyl)benzenes underwent the Davis reaction with arylacetonitriles to provide the SF5-containing benzisoxazoles. Good yields were obtained with arylacetonitriles containing the electron-neutral or electron-donor group ...
Petr Beier, Tereza Pastýříková
doaj   +1 more source

Cyclometalated iridium complexes-catalyzed acceptorless dehydrogenative coupling reaction: construction of quinoline derivatives and evaluation of their antimicrobial activities

Beilstein Journal of Organic Chemistry, 2022
The acceptorless dehydrogenative coupling (ADC) reaction is an efficient method for synthesizing quinoline and its derivatives. In this paper, various substituted quinolines were synthesized from 2-aminobenzyl alcohols and aryl/heteroaryl/alkyl secondary
Hongling Shui, Yuhong Zhong, Renshi Luo, Zhanyi Zhang, Jiuzhong Huang, Ping Yang, Nianhua Luo   +6 more
doaj   +1 more source

Quinoline-2-sulfonamide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2013
In the title compound, C9H8N2O2S, the sulfamoyl -NH2 group is involved in inter-molecular hydrogen bonding with the sulfonamide O and quinoline N atoms. In the crystal, mol-ecules are linked into dimers via pairs of N-H⋯N hydrogen bonds, forming an R 2 (2)(10) motif.
Joachim Kusz, Maria Nowak, Andrzej Maślankiewicz, Krzysztof Marciniec   +3 more
openaire   +3 more sources