Results 41 to 50 of about 49,482 (250)
Recent Strategies in the Nucleophilic Dearomatization of Pyridines, Quinolines, and Isoquinolines
Chemical ReviewsDearomatization reactions have become fundamental chemical transformations in organic synthesis since they allow for the generation of three-dimensional complexity from two-dimensional precursors, bridging arene feedstocks with alicyclic structures. When
Marcos Escolano +5 more
semanticscholar +1 more source
Acta Pharmaceutica, 2016 As a part of ongoing studies in developing new anticancer agents, novel 1,2-dihydropyridine 4, thienopyridine 5, isoquinolines 6–20, acrylamide 21, thiazolidine 22, thiazoles 23–29 and thiophenes 33–35 bearing a biologically active quinoline nucleus were
Ghorab Mostafa M. +5 more
doaj +1 more source
Repositioning of Antiparasitic Drugs for Tumor Treatment
Frontiers in Oncology, 2021 Drug repositioning is a strategy for identifying new antitumor drugs; this strategy allows existing and approved clinical drugs to be innovatively repurposed to treat tumors. Based on the similarities between parasitic diseases and cancer, recent studies
Yan-Qi Li +7 more
doaj +1 more source
Molecules, 2017 An efficient, convenient, and eco-friendly biocatalytic approach was developed for the synthesis of quinoline derivatives via the α-chymotrypsin-catalyzed Friedländer reaction. Interestingly, α-chymotrypsin exhibited higher catalytic activity in an ionic
Zhang-Gao Le +4 more
doaj +1 more source
8-(Diphenylphosphanyl)quinoline [PDF]
Acta Crystallographica Section E Structure Reports Online, 2010 The title compound, C(21)H(16)NP, is a known P-N chelator and various crystal structures of its metal complexes have been reported. However, no crystallographic evidence of the free ligand has been given to date. The phenyl rings are almost orthogonal to one another [dihedral angle = 88.9 (1)°], and they are twisted from the mean plane of the quinoline
Samik Nag +2 more
openaire +3 more sources
Photochemical C−H Hydroxyalkylation of Quinolines and Isoquinolines
Angewandte Chemie, 2019 We report herein a visible light‐mediated C−H hydroxyalkylation of quinolines and isoquinolines that proceeds via a radical path. The process exploits the excited‐state reactivity of 4‐acyl‐1,4‐dihydropyridines, which can readily generate acyl radicals ...
Bartosz Bieszczad +2 more
semanticscholar +1 more source
Guanidinium quinoline-2-carboxylate [PDF]
Acta Crystallographica Section E Structure Reports Online, 2009 In the structure of the guanidinium salt of quinaldic acid, CH(6)N(3) (+)·C(10)H(6)NO(2) (-), the asymmetric unit contains two independent cations and anions having similar inter-species hydrogen-bonding environments, which include cyclic R(2) (2)(8), R(2) (1)(6) and R(1) (2)(5) associations.
Smith, Graham, Wermuth, Urs
openaire +4 more sources
Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents
Advanced Functional Materials, EarlyView.Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras +6 more
wiley +1 more source
Molecules, 2010 The hydrogenation of 2-methylquinoline with Ir catalysts based on chiral phosphine-phosphites has been investigated. It has been observed that the reaction is very sensitive to the nature of the ligand. Optimization of the catalyst, allowed by the highly
Miguel Rubio, Antonio Pizzano
doaj +1 more source
Organic Letters, 2019 The first synthesis of 2,3-diaroyl quinolines via a formal [3 + 2 + 1] cycloaddition of enaminones, aryl methyl ketones, and aryl amines is disclosed.
Peng Zhao +6 more
semanticscholar +1 more source