Results 51 to 60 of about 9,223 (169)
Biomédica: revista del Instituto Nacional de Salud, 2018 The serotonergic and immunological hypothesis of depression proposes that certain types of excessive stress distort the relationship between the activities of the innate immune and central nervous systems, so that the stress caused by an infection, or ...
Leslie Alejandra Ramírez +5 more
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Clinical and Translational Medicine, Volume 16, Issue 11, November 2026.This Review proposes a microbiome–premetastatic brain niche axis connecting gut, lung, and intratumoral microbes with metabolites, blood–brain barrier remodeling, neuroimmune priming, and brain metastasis in NSCLC. It integrates current evidence while distinguishing established mechanisms from associations and hypotheses requiring prospective and ...
Long Liang +8 more
wiley +1 more source
The Influence of Kynurenine and Its Metabolites on Lipid Metabolism
Pteridines, 1997 Incorporation of fatty acids into phospholipids has been investigated using samples of rat liver tissue homogenate, Krebs-Ringer-phosphate buffer (pH=7.4) containing 0.3% albumin, fatty acid mixture and glycerol.
Rudzite Vera +6 more
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Improved Synthesis of N-Substituted Quinolinimides Using Microwave Irradiation
Molecules, 2000 The synthesis of several quinolinimidoacetic acid derivatives (I) by two different routes, starting from quinolinic anhydride or quinolinimide, is described.
M. M. Blanco +2 more
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MedComm, Volume 7, Issue 11, November 2026.Efferocytosis is a key process for macrophages to clear apoptotic cells, which undergoes the “ Find Me” chemotaxis signal stage, the “eat me” phagocytosis recognition stage and the “digest me” digestion stage in turn. During the aforementioned three stages, various signaling molecules released by apoptotic cells can promote the phenotypic polarization ...
Qiuping Chen +3 more
wiley +1 more source
Human brain matters: Navigating the neuropathology of COVID‐19
Brain Pathology, Volume 36, Issue 6, November 2026.Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland +4 more
wiley +1 more source
Acta Societatis Botanicorum Poloniae, 2015 Tecoma stans Juss. callus tissue grown on Murashige-Mei Lie Lin (M-L) and Murashige-Skoog (RT-k) medium supplemented with Tecoma alkaloid precursors like lysine, mevalonic acid lactone and quinolinic acid, were investigated for their alkaloid content by ...
Barbara Dohnal
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The FASEB Journal, Volume 40, Issue 20, 31 October 2026.A single exercise session transiently modulates systemic kynurenine pathway metabolism. Immediately after exercise, tryptophan decreases while kynurenine, KYN/TRP, kynurenic acid, and quinolinic acid increase. During recovery, lower tryptophan, higher KYN/TRP, and kynurenic acid remain.
Marcus Vinicius dos Santos Rangel +7 more
wiley +1 more source
Advanced Science, Volume 13, Issue 55, 5 October 2026.IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou +11 more
wiley +1 more source
Neurobiology of Disease, 2005 The effects of the peripheral benzodiazepine receptor (PBR) ligand, PK11195, were investigated in the rat striatum following the administration of quinolinic acid (QUIN).
Jae K. Ryu +2 more
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