Results 81 to 90 of about 9,006 (217)

Alpha-7 nicotinic acetylcholine receptor agonist treatment in a rat model of Huntington's disease and involvement of heme oxygenase-1

Neural Regeneration Research, 2018
Neuroinflammation is a common element involved in the pathophysiology of neurodegenerative diseases. We recently reported that repeated alpha-7 nicotinic acetylcholine receptor (α7nAChR) activations by a potent agonist such as PHA 543613 in quinolinic ...
Laura Foucault-Fruchard, Claire Tronel, Sylvie Bodard, Zuhal Gulhan, Julie Busson, Sylvie Chalon, Daniel Antier   +6 more
doaj   +1 more source

Excitotoxic degeneration of hypothalamic orexin neurons in slice culture

Neurobiology of Disease, 2004
Several lines of evidence indicate that narcolepsy, a sleep disorder, results from the loss of hypothalamic orexin (hypocretin)-containing neurons, but the mechanisms responsible for selective elimination of this neuronal population are unknown.
Hiroshi Katsuki, Akinori Akaike
doaj   +1 more source

Conversion of 3-Hydroxyanthranilic Acid to Quinolinic Acid in Presence of Rat Liver treated with 2-Acetylaminofluorene [PDF]

, 1958
E Quagliariello, Sergio Auricchio, E Rinaldi   +2 more
openalex   +1 more source

Quinolinic acid impairs mitophagy promoting microglia senescence and poor healthspan in C. elegans: a mechanism of impaired aging process. [PDF]

Biol Direct, 2023
Dongol A, Chen X, Zheng P, Seyhan ZB, Huang XF.   +4 more
europepmc   +1 more source

Systemic approaches to modifying quinolinic acid striatal lesions in rats [PDF]

, 1988
M. Flint Beal, N. W. Kowall, KJ Swartz, RJ Ferrante, Martin Jb   +4 more
openalex   +1 more source

Chronic quinolinic acid lesions in rats closely resemble Huntington's disease [PDF]

, 1991
M. F. Beal, RJ Ferrante, KJ Swartz, N. W. Kowall   +3 more
openalex   +1 more source

Cerebrospinal fluid quinolinic acid is strongly associated with delirium and mortality in hip-fracture patients. [PDF]

J Clin Invest, 2023
Watne LO, Pollmann CT, Neerland BE, Quist-Paulsen E, Halaas NB, Idland AV, Hassel B, Hassel B, Henjum K, Knapskog AB, Frihagen F, Raeder J, Godø A, Ueland PM, McCann A, Figved W, Selbæk G, Zetterberg H, Fang EF, Myrstad M, Giil LM.   +20 more
europepmc   +1 more source

Sensorineural hearing loss from quinolinic acid: A neurotoxin in middle ear effusions [PDF]

, 1994
Robert F. Yellon, Elizabeth Kirk Rose, Margaret A. Kenna, William J. Doyle, Margaretha L. Casselbrant, Warren F. Diven, Theresa L. Whiteside, J. Douglas Swarts, Melvyn P. Heyes   +8 more
openalex   +1 more source

De novo NAD+ synthesis is ineffective for NAD+ supply in axenically cultured Caenorhabditis elegans

Communications Biology
To secure an adequate nicotinamide adenine dinucleotide (NAD+) supply for survival, organisms typically rely on two complementary mechanisms: the de novo synthesis pathway and the salvage pathway.
Shihao Zhu, Runshuai Zhang, Luxia Yao, Zhirong Lin, Yanjie Li, Siyuan Li, Lianfeng Wu   +6 more
doaj   +1 more source

C-Reactive protein and the kynurenic acid to quinolinic acid ratio are independently associated with white matter integrity in major depressive disorder. [PDF]

Brain Behav Immun, 2022
Zheng H, Teague TK, Yeh FC, Burrows K, Figueroa-Hall LK, Aupperle RL, Khalsa SS, Paulus MP, Savitz J.   +8 more
europepmc   +1 more source