Results 111 to 120 of about 23,457 (205)

Cancer: Linking Powerhouses to Suicidal Bags. [PDF]

, 2017
Membrane-bound organelles are integrated into cellular networks and work together for a common goal: regulating cell metabolism, cell signaling pathways, cell fate, cellular maintenance, and pathogen defense.
Fajas, L., Martinez-Carreres, L., Nasrallah, A.   +2 more
core   +1 more source

Identification of key gut microbiota and microbial QTL in contributing to the significant differences in body weight between two Chinese local chicken breeds

Animal Genetics, Volume 57, Issue 1, February 2026.
Abstract Previous studies have identified genetic loci that are associated with both feed conversion efficiency and gut microbiota in chickens, suggesting that interactions between the host genome and gut microbiota may influence chicken growth. However, the number of microbial QTL and gut microbiota associated with chicken body weight remains largely ...
Linna Zhang, Chenglong Wang, Xiaojian Zhang, Guohui Li, Zheya Sheng   +4 more
wiley   +1 more source

Rab7-dependent regulation of goblet cell protein CLCA1 modulates gastrointestinal homeostasis

eLife
Inflammation in ulcerative colitis is typically restricted to the mucosal layer of distal gut. Disrupted mucus barrier, coupled with microbial dysbiosis, has been reported to occur prior to the onset of inflammation.
Preksha Gaur, Yesheswini Rajendran, Bhagyashree Srivastava, Manasvini Markandey, Vered Fishbain-Yoskovitz, Gayatree Mohapatra, Aamir Suhail, Shikha Chaudhary, Shaifali Tyagi, Subhash Chandra Yadav, Amit Kumar Pandey, Yifat Merbl, Avinash Bajaj, Vineet Ahuja, Chittur Srikanth   +14 more
doaj   +1 more source

MiniCORVET is a Vps8-containing hemocyte- and nephrocyte-specific early endosomal tether in Drosophila [PDF]

, 2016
Yeast studies identified two heterohexameric tethering complexes, which consist of 4 shared (Vps11, Vps16, Vps18 and Vps33) and 2 specific subunits: Vps3 and Vps8 (CORVET) versus Vps39 and Vps41 (HOPS).
Akbar, Baker, Balderhaar, Balderhaar, Bechtel, Belyaeva, Bröcker, Csordás, Gillingham, Guan, Hong, Jiang, Kim, Klinger, Koenig, Kosaka, Kurucz, Kurucz, Kümmel, Lachmann, Li, Lindmo, Lloyd, Lu, Markgraf, Morrison, Munier, Márkus, Ostrowicz, Patterson, Peplowska, Perini, Peterson, Plemel, Port, Pulipparacharuvil, Richardson, Rieder, Rusten, Schuldiner, Seals, Sevrioukov, Shestopal, Solinger, Srivastava, Südhof, Takáts, Takáts, Tanaka, van der Kant, Warner, Wartosch, Weavers, Wickner, Wucherpfennig, Wurmser, Zhang, Zhuang, Zick   +58 more
core   +3 more sources

Non‐Coding RNAs in Breast Cancer Radioresistance: Mechanisms, Functional Roles and Translational Potentials

Cell Proliferation, Volume 59, Issue 2, February 2026.
Non‐coding RNAs (ncRNAs) regulate breast cancer radioresistance via cell cycle, DNA repair and tumour microenvironment pathways. Targeting ncRNAs (e.g., HOTAIR and miR‐155) with RNA‐based therapies (ASOs and CRISPR) shows promise but faces delivery challenges.
Xiaohui Zhao, Yuting Qiu, Jie Chen, Danni Wang, Zairui Wang, Shuang Ma, Yimin Liu, Guoying Liu, Zhuofei Bi   +8 more
wiley   +1 more source

Scrambled Eggs: Apoptotic cell clearance by non-professional phagocytes in the Drosophila ovary [PDF]

, 2017
This manuscript was supported by NIH grant R01 GM060574 to KM.
McCall, Kimberly, Serizier, Sandy B.
core   +1 more source

Pulmonary Vascular Endothelial Cells in Lung Diseases: Mechanisms, Therapeutic Strategies, and Future Directions

Cell Proliferation, Volume 59, Issue 2, February 2026.
The pathogenic mechanisms of pulmonary vascular endothelial cells (VECs) in lung diseases and their multimodal therapeutic strategies. ABSTRACT Pulmonary vascular endothelial cells (VECs) are essential for the normal function of the lung, through maintaining vascular barrier integrity, regulating blood flow, and participating in inflammatory responses ...
Qianyue Liu, Hongshuai Zheng, Jing Liu, Ming Gao, Faquan Lin, Lin Liao   +5 more
wiley   +1 more source

Cloning of two genes encoding Rab7 in Paramecium.

Acta Biochimica Polonica, 2005
Rab7 is a small GTPase that plays a crucial role in the regulation of transport from early to late endosomes and lysosomes, phagosome maturation and in lysosomal biogenesis in mammalian cells. It contains conserved and unique sequence elements that mediate its function.
Liliana, Surmacz, Jolanta, Wiejak, Elzbieta, Wyroba   +2 more
openaire   +3 more sources

Salmonella Disrupts Host Endocytic Trafficking by SopD2-Mediated Inhibition of Rab7

Cell Reports, 2015
Intracellular bacterial pathogens of a diverse nature share the ability to evade host immunity by impairing trafficking of endocytic cargo to lysosomes for degradation, a process that is poorly understood.
Vanessa M. D’Costa, Virginie Braun, Marija Landekic, Rong Shi, Ariane Proteau, Laura McDonald, Miroslaw Cygler, Sergio Grinstein, John H. Brumell   +8 more
doaj   +1 more source

Regulation of autophagy by the nuclear factor κB signaling pathway in the hippocampus of rats with sepsis [PDF]

, 2015
BACKGROUND: Sepsis with brain dysfunction has contributed to an increase risk of morbidity and mortality. In its pathophysiology, both autophagy and nuclear factor κB (NF-κB) have been suggested to play important roles.
DeZhi Mu, FengYan Zhao, HuaFeng Li, XiHong Li, Yi Qu, YunJie Su   +5 more
core   +1 more source