Results 101 to 110 of about 88,529 (348)

Serum levels of interleukin-34 and RANKL as multivariable predictors of bone erosion seen by ultrasonography in patients with ankylosing spondylitis [PDF]

, 2022
Xianqian Huang, Yong Chen, Peng Yong, Minzhi Gan, Baoqing Geng, Mengya Zhu, Ying Ying   +6 more
openalex   +1 more source

Artificial Intelligence for Bone: Theory, Methods, and Applications

Advanced Intelligent Discovery, EarlyView.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan, Haicang Zhang, Liping Tong, Di Chen   +3 more
wiley   +1 more source

Emerging Importance of Supply Chain Attitudes

Chemical Engineering Transactions
The nature of relationships within supply chains and understanding the dynamics of interactions between the supply chain members are key factors in today's globalised economy, where speed, efficiency and flexibility in the flow of goods and information ...
Andrea Rankl, Péter Németh
doaj  

Mitigation of Rheumatic Arthritis in a Rat Model via Transdermal Delivery of Dapoxetine HCl Amalgamated as a Nanoplatform: In vitro and in vivo Assessment

International Journal of Nanomedicine, 2020
Heba Farouk Salem,1 Mohamed Mahmoud Nafady,2 Rasha Mostafa Kharshoum,1 Omnia Ahmed Abd el-Ghafar,3 Hanan Osman Farouk2 1Pharmaceutics and Industrial Pharmacy Department, Faculty of Pharmacy, Beni- Suef University, Beni Suef, Egypt; 2Pharmaceutics and ...
Salem HF, Nafady MM, Kharshoum RM, Abd el-Ghafar OA, Farouk HO   +4 more
doaj  

EFFECT OF GOLIMUMAB ON IMMUNOLOGICAL MARKERS FOR BONE METABOLISM AND ON ARTERIAL STIFFNESS IN PATIENTS WITH RHEUMATOID ARTHRITIS

Научно-практическая ревматология, 2018
Objective: to evaluate the effect of golimumab (GLM) on the receptor activator of NF-κB ligand (RANKL)/osteoprotegerin (OPG) transmembrane molecular system and arterial stiffness in patients with rheumatoid arthritis (RA).Subjects and methods. Thirty-six
L. A. Knyazeva, N. Damjanov, L. I. Knyazeva, N. S. Meshcherina, I. I. Goryainov   +4 more
doaj   +1 more source

An in vivo assay for osteoclast activity using mouse calvaria

Animal Models and Experimental Medicine, EarlyView.
This study describes a novel method for measuring osteoclast‐mediated bone resorption in vivo using a mouse model. Localized injection of RANKL in a basement membrane matrix above the cranium induced osteoclast‐mediated bone resorption. Utilizing micro‐computed tomography and a semiautomated three‐dimensional analysis program, osteoclast resorption pit
Christopher Grieg, Maya Deza Culbertson, J. Patrick O'Connor   +2 more
wiley   +1 more source

Baicalin Ameliorates Dexamethasone-Induced Osteoporosis by Regulation of the RANK/RANKL/OPG Signaling Pathway

Drug Design, Development and Therapy, 2020
Ye Zhao, 1, 2 Hui-Ling Wang, 1 Tong-Tong Li, 1 Fei Yang, 1 Chi-Meng Tzeng 1 1School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing 211800, People’s Republic of China; 2Jiangsu Synergetic Innovation Center for Advanced Bio ...
Zhao Y, Wang HL, Li TT, Yang F, Tzeng CM
doaj  

Indicators of the osteoclastogenesis system in men with different clinical types of ankylosing spondylitis

Современная ревматология, 2015
Objective: to evaluate the osteoclastogenesis regulatory system – osteoprotegerin/receptor activator of nuclear factor-κβ ligand (OPG/RANKL) system – in men with different clinical types of ankylosing spondylitis (AS).Subjects and methods.
T. A. Raskina, O. A. Pirogova, O. V. Zobnina, G. A. Pintova   +3 more
doaj   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

Exploring the Role of Exosomes in Accelerating Orthodontic Tooth Movement

Journal of Pharmacy and Bioallied Sciences
Background: Alveolar bone remodeling is a complicated biological process that is involved in orthodontic tooth movement (OTM). Recent studies have shown how exosomes, which are cell-secreted nanovesicles, influence cellular communication and encourage ...
Abdalwhab Zwiri, Mohammad Khursheed Alam, Mohammad Younis Hajeer, Ebtehal Dhyab M. Alserhani, Dalia Abdulrahman Alanazi, Jinan Mohammed Alanazi, Nor Farid Bin Mohd Noor, Zafrina Islam   +7 more
doaj   +1 more source