Results 151 to 160 of about 88,529 (348)
The Inhibition of RANKL-Induced Osteoclastogenesis through the Suppression of p38 Signaling Pathway by Naringenin and Attenuation of Titanium-Particle-Induced Osteolysis [PDF]
, 2014 Wengang Wang +11 more
openalex +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT This study evaluated the effects of puerarin and adipose‐derived stem cells (ADSCs), alone or combined, on p38MAPK activity, alveolar bone preservation, and inflammatory responses in a rat periodontitis (PD) model and in vitro. ADSCs were exposed to various puerarin concentrations to assess cell proliferation, osteogenic differentiation, and ...
Ting Yang, Xu Zhang, Liang‐Fu Zhang
wiley +1 more source
PM&R, EarlyView.Abstract Background Osteoporosis fractures pose a significant public health concern, leading to substantial morbidity and mortality rates. The emerging evidence on the potential link between gut microbiota, proteins, and osteoporosis fractures suggests a complex relationship that warrants further investigation.
Qiong Wang +6 more
wiley +1 more source
New Advances of Degradable Magnesium‐Based Metal Biomaterials in the Field of Orthopedics
Rare Metals, EarlyView.ABSTRACT Based on their outstanding biomechanical properties and superior osteogenic activity, magnesium (Mg) and its alloys have been extensively investigated for their biocompatibility and therapeutic efficacy in treating fractures and bone defects.
Jia‐Nan Yu +8 more
wiley +1 more source
Rare Metals, EarlyView.ABSTRACT The limited osteogenic capacity of magnesium phosphate cement (MPC) has constrained its biomedical applications, underscoring the necessity to develop MPC with enhanced physical properties and bone‐forming capabilities. In this study, a multifunctional MPC system was developed by incorporating zoledronic acid‐loaded near‐infrared (NIR ...
Bin Wang +8 more
wiley +1 more source
A Cell‐Intrinsic Role for RANK in Regulatory T Cells of the Human Thymus [PDF]
Eur J ImmunolWe identified RANK (TNFRSF11a) expression in human thymic FOXP3+ Tregs, revealing a previously unknown role for the RANK‐RANKL axis in human tTreg development. We show that IL‐2 and IL‐15 can drive RANK expression in CD4+ tTregs, which in turn may modulate their maturation and proliferation within the thymic environment. Created in BioRender. Biorender,
Junginger Z +5 more
europepmc +2 more sources
Mechanisms of Disease: roles of OPG, RANKL and RANK in the pathophysiology of skeletal metastasis [PDF]
, 2006 Julie M. Blair +3 more
openalex +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objectives Acquired cholesteatoma is an abnormal and invasive growth of keratinized squamous epithelial cells in the middle ear. The study aims to explore the role of exosomal miRNAs in the pathogenesis of acquired cholesteatoma and their potential in clinical application.
Qi Tang +12 more
wiley +1 more source
The Policy and Politics of Improving Standards in the English Private Rented Sector
The Political Quarterly, EarlyView.Abstract The standard of existing homes in the English private rented sector (PRS) presents several challenges. As the sector has expanded, issues of inadequate renovation, maintenance and upgrading have assumed greater salience. Research has also highlighted enforcement challenges which make it more difficult to raise property standards and improve ...
Alice Earley, Alex Marsh, Ken Gibb
wiley +1 more source