A Truncated Serpin D1 Variant Regulates Adseverin-Dependent Actin Severing and Is Required for Osteoclastogenesis. [PDF]
Wang Y +8 more
europepmc +1 more source
Chinese Guideline on Risk Management of Osteoporosis in the General Public
Summary of the background, key recommendations, and expected impact of the public guideline for osteoporosis risk management. ABSTRACT Background Osteoporosis is a common chronic skeletal disorder characterized by decreased bone mass and microarchitectural deterioration, resulting in increased fragility and fracture risk. With rapid population aging in
Shiyong Zhang +84 more
wiley +1 more source
RANKL-convergent osteoimmune network framework in osteoporosis: integrating macrophage activation, T-cell imbalance, and cytokine crosstalk. [PDF]
Zheng K +6 more
europepmc +1 more source
Role of the Antioxidant Lycopene in Bone Health: Emphasis on the RANKL/RANK/OPG Signaling Pathway. [PDF]
Esmaili H +3 more
europepmc +1 more source
RANKL Attenuates Sepsis\u2010Associated Acute Lung Injury Through the OPG/RANKL/RANK/TLR4 Pathway
BACKGROUND: Sepsis\u2010associated acute lung injury (SA\u2010ALI) is a critical disease marked by a dysregulated immune response to infection, causing organ dysfunction.
Chen, Weilin +3 more
core +1 more source
Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases
Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva +2 more
wiley +1 more source
WDR23 prevents bone loss by promoting autophagic degradation of TRAF6 in osteoclastogenesis. [PDF]
Park HW +11 more
europepmc +1 more source
Etiology, pathogenesis and treatment of peri‐implantitis: A European perspective
Abstract Peri‐implantitis is a plaque‐associated pathological condition occurring in tissues around dental implants. It is characterized by inflammation in the peri‐implant mucosa and progressive loss of supporting bone. Over the last 30 years, peri‐implantitis has become a major disease burden in dentistry.
Tord Berglundh +3 more
wiley +1 more source
Asarinin Inhibits RANKL-Induced Osteoclast Differentiation by Targeting the p38/ERK-c-Fos-NFATc1 Axis. [PDF]
Zhang L +8 more
europepmc +1 more source
The role of acquired host immunity in periodontal diseases
Abstract The aim of this narrative review is to relate the contribution of European researchers to the complex topic of the host immune system in periodontal disease, focusing on acquired immunity. Other chapters in this volume will address the genetics and autoantibody responses and other forms of immunity to periodontal disease.
Denis F. Kinane +2 more
wiley +1 more source

