Results 171 to 180 of about 59,926 (291)

Cilostazol ameliorates high glucose-induced osteoblast dysfunction by modulating mitogen-activated protein kinase signaling and the OPG/RANKL axis. [PDF]

Exp Ther Med
Kim JE, Park H.
europepmc   +1 more source

Periodontal Infectogenomics in Africa: The Biological Case for a Population‐Centred Research Agenda

Journal of Periodontal Research, EarlyView.
African populations harbour the greatest human genetic diversity on earth and carry the highest global burden of severe periodontitis, yet their absence from periodontal infectogenomics represents a biological limitation of the field with profound implications for host‐microbe interaction research.
Salma Kabbashi, Manogari Chetty
wiley   +1 more source

Reprogramming bone homeostasis: The recoupling-oriented framework of bidirectional regulation strategies for osteoporosis. [PDF]

iScience
Niu J, Li Z, Zou Y, Wang Z, Kang J, Zhang Y, Wang S, Liu R, Han X.   +8 more
europepmc   +1 more source

Combined Effects of Romosozumab and Zoledronate on the Development of Osteonecrosis of the Jaw

Oral Diseases, EarlyView.
ABSTRACT Objective This study aimed to assess the occurrence of medication‐related osteonecrosis of the jaw (MRONJ) in mice following the sequential administration of romosozumab and zoledronate and to confirm their inhibitory effects on osteoclast differentiation in vitro.
Hae‐Seo Park, Shihyun Kim, Seo‐Yeong An, Reuben H. Kim, Jongho Choi, Moon‐Young Kim   +5 more
wiley   +1 more source

The Relationship Between Orthodontic Malocclusion Severity and Periodontal Clinical and Biochemical Parameters in Adolescents: A Cross-Sectional Study. [PDF]

Diagnostics (Basel)
Yorgancilar N, Kose T, Uygun S, Kose O, Akyildiz K, Yilmaz A.   +5 more
europepmc   +1 more source

Oxidative Stress–Driven Alterations in FoxO‐1 and MMP‐9 Activity in Smoking‐Associated Periodontitis

Oral Diseases, EarlyView.
ABSTRACT Objectives Smoking disrupts oxidative balance and is a major risk factor for periodontitis. Forkhead box protein O‐1 (FoxO‐1) regulates antioxidant defense, yet its contribution to smoking‐associated periodontal breakdown is unclear. This cross‐sectional case–control study assessed reactive oxygen species (ROS), matrix metalloproteinase‐9 (MMP‐
Fatma Oner, Fatma Soysal, Ceren Gokmenoglu, Muhittin A. Serdar, Zeliha Guney   +4 more
wiley   +1 more source

Intratumoral Administration of Recombinant Murine Interleukin‐12 Prevents Tumor Progression and Bone Invasion

Oral Diseases, EarlyView.
ABSTRACT Objective Oral squamous cell carcinoma (OSCC) frequently invades the mandibular bone, leading to metastasis and poor prognosis. This study aimed to evaluate the therapeutic effects of locally administered interleukin‐12 (IL‐12) using an immunocompetent mouse model mimicking the clinical features of mandibular bone invasion. Methods The effects
Shun Kasahara, Miki Kashiwagi, Toshihiro Inubushi, Akinari Sugauchi, Wu Deyong, Kyoko Kurioka, Kazuaki Miyagawa, Takuma Matsuda, Soju Seki, Mikihiko Kogo, Susumu Tanaka, Toshihiro Uchihashi   +11 more
wiley   +1 more source

Research Progress on Signaling Pathways in Breast Cancer Bone Metastasis. [PDF]

Oncol Res
Li Y, Li T, Liang F, Kuang L, Li Y, Li H.   +5 more
europepmc   +1 more source

Algorithm for Surgical Management in Patients in Treatment With Medication Associated With Osteonecrosis of the Jaws

Oral Surgery, EarlyView.
ABSTRACT Background Osteonecrosis of the jaws is associated with various drugs, including antiresorptives such as bisphosphonates and denosumab, as well as antiangiogenics. These drugs are used for the treatment of multiple diseases, notably osteoporosis, bone metastases, Paget's disease, osteogenesis imperfecta, malignant hypocalcaemia, among others ...
Rodríguez Naranjo Julia Alexandra, Gómez Hernández Kevin Andrew, Cabrera del Cid María Fernanda, Jerez Robalino James Philippe   +3 more
wiley   +1 more source

Gut microbiota-immune-bone axis in osteoporosis: mechanisms and intervention strategies. [PDF]

Front Pharmacol
Huang M, Xie B, Liu H.
europepmc   +1 more source