Fluid shear stress activates c-Src and promotes RANKL localization in the plasma membrane in osteoblast-like MC3T3-E1 cells. [PDF]
BBA AdvMatsubara T, Yoshimura A, Kokabu S.
europepmc +1 more source
Platelet‐Rich Fibrins as Local Drug‐Delivery Carriers
Journal of Periodontal Research, EarlyView.Autologous platelet concentrates (APCs), particularly platelet‐rich fibrin (PRF), act as biologically active fibrin scaffolds, capable of entrapping and gradually releasing therapeutic agents in oral and periodontal therapy. The incorporation of bioactive compounds, such as antibiotics, antifungals, vitamins, antidiabetic drugs, and exosomes, enhances ...
Karim M. Fawzy El‐Sayed +1 more
wiley +1 more source
Path Analysis Results on Bone Markers That Influence Accelerated Bone Remodeling: An Experimental Study. [PDF]
Clin Exp Dent ResDewi RK +8 more
europepmc +1 more source
MRONJ Risk Related to Dental Implants in Osteoporosis Treated With Denosumab: A Systematic Review
Oral Diseases, EarlyView.ABSTRACT Objectives The aim of this systematic review was to assess the impact of dental implants in osteoporotic patients undergoing treatment with denosumab on MRONJ development, considering both implant surgery‐triggered osteonecrosis (ISTO) and implant presence‐triggered osteonecrosis (IPTO).
Rebheca Maria Pereira Santos +4 more
wiley +1 more source
Significant association of RANKL polymorphisms with bone metastasis among patients with breast cancer. [PDF]
Front OncolLian H, Zhou S, He H, Liu Q, Zhao J.
europepmc +1 more source
Combined Effects of Romosozumab and Zoledronate on the Development of Osteonecrosis of the Jaw
Oral Diseases, EarlyView.ABSTRACT Objective This study aimed to assess the occurrence of medication‐related osteonecrosis of the jaw (MRONJ) in mice following the sequential administration of romosozumab and zoledronate and to confirm their inhibitory effects on osteoclast differentiation in vitro.
Hae‐Seo Park +5 more
wiley +1 more source
The Presence of SFRP1 Reduces the High Risk of Metastasis in RANKL-Expressing Canine Mammary Cancers. [PDF]
Animals (Basel)Durys N +3 more
europepmc +1 more source
RANKL Attenuates Sepsis-Associated Acute Lung Injury Through the OPG/RANKL/RANK/TLR4 Pathway. [PDF]
Immun Inflamm DisNiu X, Turson N, Chen W, Li H.
europepmc +1 more source
Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases
Periodontology 2000, EarlyView.Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva +2 more
wiley +1 more source