Correlation of the differential expressions of RANK, RANKL, and OPG with obesity in the elderly population in Xinjiang [PDF]
Open MedicineObesity has been recognized as a global epidemic and public health crisis. The prevalence of obesity has tripled since 1975, especially in the elderly population.
Liu Jinling +8 more
doaj +2 more sources
Regulation of neurite growth by tumour necrosis superfamily member RANKL [PDF]
Open Biology, 2013 RANKL (receptor-activator of NF-κB ligand, TNFSF11) is a member of the TNF superfamily that regulates bone remodelling and the development of the thymus, lymph nodes and mammary glands.
Humberto Gutierrez +5 more
doaj +2 more sources
Drug Design, Development and Therapy, 2020 Ye Zhao, 1, 2 Hui-Ling Wang, 1 Tong-Tong Li, 1 Fei Yang, 1 Chi-Meng Tzeng 1 1School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing 211800, People’s Republic of China; 2Jiangsu Synergetic Innovation Center for Advanced Bio ...
Zhao Y, Wang HL, Li TT, Yang F, Tzeng CM
doaj +2 more sources
ANXA2 Regulates RANKL-Induced Osteoclast Differentiation Through STAT3 Signaling in Breast Cancer. [PDF]
Breast Cancer (Dove Med Press)Yuan J, Xin F, Wang R.
europepmc +2 more sources
RANKL biology: bone metabolism, the immune system, and beyond [PDF]
Inflammation and Regeneration, 2020 Receptor activator of NF-κB (RANK) ligand (RANKL) induces the differentiation of monocyte/macrophage–lineage cells into the bone–resorbing cells called osteoclasts.
T. Ono +3 more
openalex +2 more sources
Development of Functional Microfold (M) Cells from Intestinal Stem Cells in Primary Human Enteroids. [PDF]
, 2016 Background & aimsIntestinal microfold (M) cells are specialized epithelial cells that act as gatekeepers of luminal antigens in the intestinal tract.
Dunn, James CY +11 more
core +12 more sources
ارتباط بین غلظت سرمیRANKL با اختلالات قلبی در بیماران بتا تالاسمی ماژور [PDF]
Majallah-i Dānishkadah-i Pizishkī-i Dānishgāh-i ̒ Ulūm-i Pizishkī-i Mashhad., 2020 چکیده مقدمه: بتا تالاسمی ماژور نوعی اختلال اتوزومال مغلوب است که با اریتروپوئز غیر موثر شناخته میشود. تزریق مداوم و ناتوانی بدن در حذف آهن در بدن منجر به اضافه بار آهن شده که باعث ایجاد صدمه به بافت قلب میشود.
الهام محمودی +5 more
doaj +1 more source
The RANK–RANKL–OPG System: A Multifaceted Regulator of Homeostasis, Immunity, and Cancer
Medicina, 2023 The RANK–RANKL–OPG system is a complex signaling pathway that plays a critical role in bone metabolism, mammary epithelial cell development, immune function, and cancer. RANKL is a ligand that binds to RANK, a receptor expressed on osteoclasts, dendritic
Diego de Leon-Oliva +12 more
semanticscholar +1 more source
Bad to the bone: B cell acute lymphoblastic leukemia cells mediate bone destruction
Molecular & Cellular Oncology, 2021 Skeletal morbidities continue to cause acute and long-term burdens for B-ALL patients underscoring the need to identify the mechanisms underlying these processes and to develop effective therapies.
Sujeetha A. Rajakumar, Jayne S. Danska
doaj +1 more source
The Roles of RANK/RANKL/OPG in Cardiac, Skeletal, and Smooth Muscles in Health and Disease
Frontiers in Cell and Developmental Biology, 2022 Although their physiology and functions are very different, bones, skeletal and smooth muscles, as well as the heart have the same embryonic origin. Skeletal muscles and bones interact with each other to enable breathing, kinesis, and the maintenance of ...
L. Marcadet +3 more
semanticscholar +1 more source