Results 11 to 20 of about 81,008 (204)
Inhibition of RANKL-Induced Osteoclastogenesis by Novel Mutant RANKL [PDF]
International Journal of Molecular Sciences, 2021 Background: Recently, it was reported that leucine-rich repeat-containing G-protein-coupled receptor 4 (LGR4, also called GPR48) is another receptor for RANKL and was shown to compete with RANK to bind RANKL and suppress canonical RANK signaling during osteoclast differentiation.
Yuria Jang +4 more
openaire +2 more sources
Development of Functional Microfold (M) Cells from Intestinal Stem Cells in Primary Human Enteroids. [PDF]
, 2016 Background & aimsIntestinal microfold (M) cells are specialized epithelial cells that act as gatekeepers of luminal antigens in the intestinal tract.
Dunn, James CY +11 more
core +12 more sources
OSTEOPROTEGERIN, RANK, RANKL [PDF]
Biomedical Papers, 2001 Osteoprotegerin, RANK (Receptor Activator of Nuclear factor kappa B) and RANKL (Receptor Activator of Nuclear faktor kappa B ligand) became the aim of intensive research. RANK is considered as a hematopoietic surface receptor controlling osteoclastogenesis and calcium metabolism.
D, Stejskal +5 more
openaire +2 more sources
Bone matrix components activate the NLRP3 inflammasome and promote osteoclast differentiation [PDF]
, 2017 The NLRP3 inflammasome senses a variety of signals referred to as danger associated molecular patterns (DAMPs), including those triggered by crystalline particulates or degradation products of extracellular matrix. Since some DAMPs confer tissue-specific
Abu-Amer, Yousef +9 more
core +2 more sources
médecine/sciences, 2008 Given the increasing risk of fractures with aging in western countries, there is a need for the development of safe and efficient anti-osteoporotic drugs for the prevention and treatment of osteoporosis. Recent studies have provided evidence for an essential role of RANKL (Receptor Activator of Nuclear Factor-kappa B Ligand) and its decoy receptor ...
Pierre Marie, Philippe Halbout
openaire +1 more source
Mathematical modelling of the pathogenesis of multiple myeloma-induced bone disease [PDF]
, 2014 Multiple myeloma (MM) is the second most common haematological malignancy and results in destructive bone lesions. The interaction between MM cells and the bone microenvironment plays an important role in the development of the tumour cells and MM ...
Blum B +6 more
core +1 more source
Activated γδ T cells inhibit osteoclast differentiation and resorptive activity in vitro [PDF]
, 2013 Peer reviewedPublisher ...
Pappalardo, A., Thompson, K.
core +1 more source
International Journal of Nanomedicine, 2023 Lin Liu, Haifeng Tang, Yanjun Wang Department of Emergency, Honghui Hospital of Xi’an Jiaotong University, Xi’an, 710054, People’s Republic of ChinaCorrespondence: Yanjun Wang; Haifeng Tang, Department of Emergency, Honghui Hospital of Xi’an Jiaotong ...
Liu L, Tang H, Wang Y
doaj
Osteoclast activity in osteoporosis mandibular bone based on RANKL and osteoprotegerin ratio. [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2021 Context: Osteoporosis occurs not only in the lumbar bone, femur, and radius but also occurs in the mandibular bone. Therefore, osteoporosis is a disease that required attention from the dentists.
Mefina Kuntjoro +5 more
doaj
Regulation of neurite growth by tumour necrosis superfamily member RANKL [PDF]
Open Biology, 2013 RANKL (receptor-activator of NF-κB ligand, TNFSF11) is a member of the TNF superfamily that regulates bone remodelling and the development of the thymus, lymph nodes and mammary glands.
Humberto Gutierrez +5 more
doaj +1 more source