Results 41 to 50 of about 41,957 (263)
Хирургия позвоночника, 2021 Objective. To assess the effect of the combined treatment method including preoperative denosumab therapy on the results of treatment of patients with giant cell tumors of the spine. Material and Methods.
Anastasia A. Tararykova +6 more
doaj +1 more source
Advanced Science, EarlyView.Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae +5 more
wiley +1 more source
Internal inflammatory root resorption in permanent teeth
Эндодонтия Today, 2020 Internal inflammatory root resorption is a rare find in everyday dental practice. Also, it is known to be an accident discovery. Analysis of publications of domestic and foreign periodicals and of biochemistry, histology, microbiology textbooks has ...
doaj
Oroxin B Attenuates Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Formation and Activity
Drug Design, Development and Therapy, 2021 Jun-ming Huang, Chen-zhong Wang, Shun-yi Lu, Zhe Wang, Zuo-qin Yan Department of Orthopaedics, Zhongshan Hospital, Fudan University, Shanghai, 200032, People’s Republic of ChinaCorrespondence: Zuo-qin Yan 180 Feng Lin Road, Xuhui District, Shanghai ...
Huang JM, Wang CZ, Lu SY, Wang Z, Yan ZQ
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Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis
Arthritis &Rheumatology, EarlyView.Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm +2 more
wiley +1 more source
Научно-практическая ревматология, 2018 Objective: to evaluate the effect of golimumab (GLM) on the receptor activator of NF-κB ligand (RANKL)/osteoprotegerin (OPG) transmembrane molecular system and arterial stiffness in patients with rheumatoid arthritis (RA).Subjects and methods. Thirty-six
L. A. Knyazeva +4 more
doaj +1 more source
Biology of RANK, RANKL, and osteoprotegerin [PDF]
Arthritis Research & Therapy, 2007 The discovery of the receptor activator of nuclear factor-kappaB ligand (RANKL)/RANK/osteoprotegerin (OPG) system and its role in the regulation of bone resorption exemplifies how both serendipity and a logic-based approach can identify factors that regulate cell function. Before this discovery in the mid to late 1990s, it had long been recognized that
Boyce, Brendan F, Xing, Lianping
openaire +2 more sources
Arthritis &Rheumatology, EarlyView.Objective Carbamylation, a nonenzymatic post‐translational modification, contributes to rheumatoid arthritis (RA) pathogenesis. Anti‐carbamylated protein antibodies (anti‐CarP) occur in around 50% of patients with RA and associate with greater joint damage. Neutrophil extracellular traps (NETs) are a major source of carbamylated autoantigens. We sought
Shuichiro Nakabo +9 more
wiley +1 more source
Современная ревматология, 2015 Objective: to evaluate the osteoclastogenesis regulatory system – osteoprotegerin/receptor activator of nuclear factor-κβ ligand (OPG/RANKL) system – in men with different clinical types of ankylosing spondylitis (AS).Subjects and methods.
T. A. Raskina +3 more
doaj +1 more source
RANKL inhibits activation of hepatic stellate cells during hepatic fibrosis in mice
陆军军医大学学报, 2023 Objective To explore the biological role of receptor activator of nuclear factor kappa-B ligand (RANKL) in the activation of hepatic stellate cells (HSCs) and the process of hepatic fibrosis.
ZHOU Lijia +4 more
doaj +1 more source