Results 31 to 40 of about 81,880 (297)

Serum fetuin-A and RANKL levels in patients with early stage breast cancer [PDF]

open access: yesJournal of Medical Biochemistry, 2023
Background: Breast cancer (BC) is the primary cause of mortality due to cancer in females around the world. Fetuin-A is known to increase metastases over signals and peroxisomes related with growing. Receptor activator of nuclear factor-kB ligand (RANKL)
Afsar Cigdem Usul   +7 more
doaj  

Serum RANKL, osteoprotegerin (OPG), and RANKL/OPG ratio in nephrotic children [PDF]

open access: yesPediatric Nephrology, 2010
Receptor activator of NF-kB ligand (RANKL) and osteoprotegerin (OPG) play key roles in the pathogenesis of glucocorticoid-induced osteoporosis (GIO). The aim of our study was to determine whether the cumulative glucocorticoid dose (CGCS) in children with idiopathic nephrotic syndrome (INS) has any effect on the concentration of serum RANKL and OPG and ...
Wasilewska, Anna   +2 more
openaire   +2 more sources

Changes in Bone Metabolism and Structure in Primary Hyperparathyroidism

open access: yesActa Medica Bulgarica, 2020
Parathyroid hormone (PTH) is a key regulator of bone turnover. Depending on the duration of action, the hormone causes catabolic and anabolic effects by binding with specific receptors (PTHR1) in the bone.
Yankova I., Shinkov A., Kovatcheva R.
doaj   +1 more source

Detection Of Rankl Positive Cells in Gingival Tissue in Healthy & Chronic Periodontal Disease Patients -A Comparative Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Aim & Objective: The receptor activator of NF-kappa B ligand (RANKL) and its decoy receptor, osteoprotegerin (OPG), are the important proteins implicated in osteoclastogenesis.
J. BHUVANESWARRI   +2 more
doaj   +1 more source

Investigation of the SH3BP2 Gene Mutation in Cherubism [PDF]

open access: yes, 2008
Cherubism is a rare developmental lesion of the jaw that is generally inherited as an autosomal dominant trait. Recent studies have revealed point mutations in the SH3BP2 gene in cherubism patients.
Ahn, Sang-Gun   +5 more
core   +1 more source

Guizhi-Shaoyao-Zhimu decoction attenuates bone erosion in rats that have collagen-induced arthritis via modulating NF‐κB signalling to suppress osteoclastogenesis

open access: yesPharmaceutical Biology, 2021
Context Guizhi-Shaoyao-Zhimu decoction (GSZD) is commonly used to treat rheumatoid arthritis (RA), but its mechanism is unclear. Objective To investigate the effect of GSZD on bone erosion in type II collagen (CII)-induced arthritis (CIA) in rats and to ...
Shu-jun Wei   +6 more
doaj   +1 more source

Effect of Low-magnitude, High-frequency Vibration on Osteocytes in the Regulation of Osteoclasts [PDF]

open access: yes, 2010
Osteocytes are well evidenced to be the major mechanosensor in bone, responsible for sending signals to the effector cells (osteoblasts and osteoclasts) that carry out bone formation and resorption. Consistent with this hypothesis, it has been shown that
Al-Dujaili, Saja   +5 more
core   +2 more sources

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

open access: yesAdvanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad   +2 more
wiley   +1 more source

RANKL Expression in Periodontal Disease: Where Does RANKL Come from?

open access: yesBioMed Research International, 2014
Periodontitis is an inflammatory disease characterized by periodontal pocket formation and alveolar bone resorption. Periodontal bone resorption is induced by osteoclasts and receptor activator of nuclear factor-κB ligand (RANKL) which is an essential and central regulator of osteoclast development and osteoclast function.
Bin Chen   +5 more
openaire   +4 more sources

Mechanisms underlying bone loss associated with gut inflammation [PDF]

open access: yes, 2019
Patients with gastrointestinal diseases frequently suffer from skeletal abnormality, characterized by reduced bone mineral density, increased fracture risk, and/or joint inflammation.
Abu-Amer, Yousef, Arra, Manoj, Ke, Ke
core   +2 more sources

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