Results 21 to 30 of about 41,691 (265)
Osteopetrosis rescue upon RANKL administration to Rankl−/− mice: A new therapy for human RANKL-dependent ARO [PDF]
Journal of Bone and Mineral Research, 2012 Abstract In the last decades the molecular basis of monogenic diseases has been largely unraveled, although their treatment has often remained unsatisfactory. Autosomal recessive osteopetrosis (ARO) belongs to the small group of genetic diseases that are usually treated with hematopoietic stem cell transplantation (HSCT).
LO IACONO N +21 more
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The Effects of Acute Exercise on RANKL/RANK/OPG Pathway and Bone Metabolic Markers in Healthy College Female [PDF]
운동과학, 2018 PURPOSE The purpose of this study was to examine the effects of acute exercise with difference Intensitis on RANKL/RANK/OPG pathway and bone metabolic markers in healthy college female. METHODS Ten healthy college females (aged 21.5±1.84 years; VO2max 37.
Ji-Yeon Kim +5 more
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médecine/sciences, 2008 Given the increasing risk of fractures with aging in western countries, there is a need for the development of safe and efficient anti-osteoporotic drugs for the prevention and treatment of osteoporosis. Recent studies have provided evidence for an essential role of RANKL (Receptor Activator of Nuclear Factor-kappa B Ligand) and its decoy receptor ...
Pierre Marie, Philippe Halbout
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M CELLS ARE THE IMPORTANT POST IN THE INITIATION OF IMMUNE RESPONSE IN INTESTINE
Инфекция и иммунитет, 2018 Microfold cells (M cells) are specialized intestinal epithelial cells that initiate mucosal immune responses. These unique phagocytic epithelial cells are specialized for the transfer of a broad range of particulate antigens and microorganisms across the
A. S. Bykov +7 more
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Inhibition of RANK signaling as a potential immunotherapy in breast cancer
OncoImmunology, 2021 RANK signaling in mouse mammary tumor cells exerts an immunosuppressive environment by promoting the infiltration of pro-tumorigenic neutrophils and preventing CD8 T cell recruitment.
C Gómez-Aleza, E González-Suárez
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RANK–RANKL signalling in cancer [PDF]
Bioscience Reports, 2016 Oncogenic events combined with a favourable environment are the two main factors in the oncological process. The tumour microenvironment is composed of a complex, interconnected network of protagonists, including soluble factors such as cytokines, extracellular matrix components, interacting with fibroblasts, endothelial cells, immune cells and various
Heymann, D. +4 more
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International Journal of Nanomedicine, 2023 Lin Liu, Haifeng Tang, Yanjun Wang Department of Emergency, Honghui Hospital of Xi’an Jiaotong University, Xi’an, 710054, People’s Republic of ChinaCorrespondence: Yanjun Wang; Haifeng Tang, Department of Emergency, Honghui Hospital of Xi’an Jiaotong ...
Liu L, Tang H, Wang Y
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Osteoclast activity in osteoporosis mandibular bone based on RANKL and osteoprotegerin ratio. [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2021 Context: Osteoporosis occurs not only in the lumbar bone, femur, and radius but also occurs in the mandibular bone. Therefore, osteoporosis is a disease that required attention from the dentists.
Mefina Kuntjoro +5 more
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Regulation of neurite growth by tumour necrosis superfamily member RANKL [PDF]
Open Biology, 2013 RANKL (receptor-activator of NF-κB ligand, TNFSF11) is a member of the TNF superfamily that regulates bone remodelling and the development of the thymus, lymph nodes and mammary glands.
Humberto Gutierrez +5 more
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陆军军医大学学报, 2023 Objective To investigate the mechanisms of 1, 25(OH)2D3 on joint inflammation and bone destruction in a mouse model of collagen-induced arthritis (CIA). Methods Thirty DBA/1J mice were equally allocated into control, CIA and intervention (VD) groups. The
QI Kun, LIU Yun, TANG Tao, LUO Xiwen
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