Results 21 to 30 of about 81,880 (297)
Osteoclast activity in osteoporosis mandibular bone based on RANKL and osteoprotegerin ratio. [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2021 Context: Osteoporosis occurs not only in the lumbar bone, femur, and radius but also occurs in the mandibular bone. Therefore, osteoporosis is a disease that required attention from the dentists.
Mefina Kuntjoro +5 more
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Regulation of neurite growth by tumour necrosis superfamily member RANKL [PDF]
Open Biology, 2013 RANKL (receptor-activator of NF-κB ligand, TNFSF11) is a member of the TNF superfamily that regulates bone remodelling and the development of the thymus, lymph nodes and mammary glands.
Humberto Gutierrez +5 more
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Gerontology, 2015 Receptor activator of nuclear factor κB (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL
Vanja, Nagy, Josef M, Penninger
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Mathematical modelling of the pathogenesis of multiple myeloma-induced bone disease [PDF]
, 2014 Multiple myeloma (MM) is the second most common haematological malignancy and results in destructive bone lesions. The interaction between MM cells and the bone microenvironment plays an important role in the development of the tumour cells and MM ...
Blum B +6 more
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陆军军医大学学报, 2023 Objective To investigate the mechanisms of 1, 25(OH)2D3 on joint inflammation and bone destruction in a mouse model of collagen-induced arthritis (CIA). Methods Thirty DBA/1J mice were equally allocated into control, CIA and intervention (VD) groups. The
QI Kun, LIU Yun, TANG Tao, LUO Xiwen
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Osteopetrosis rescue upon RANKL administration to Rankl−/− mice: A new therapy for human RANKL-dependent ARO [PDF]
Journal of Bone and Mineral Research, 2012 Abstract In the last decades the molecular basis of monogenic diseases has been largely unraveled, although their treatment has often remained unsatisfactory. Autosomal recessive osteopetrosis (ARO) belongs to the small group of genetic diseases that are usually treated with hematopoietic stem cell transplantation (HSCT).
LO IACONO N +21 more
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Annals of Glaciology, 2016 Snow cover and glaciers in the Karakoram region are important freshwater resources for many down-river communities as they provide water for irrigation and hydropower.
Melanie Rankl, Matthias Braun
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RANK–RANKL signalling in cancer [PDF]
Bioscience Reports, 2016 Oncogenic events combined with a favourable environment are the two main factors in the oncological process. The tumour microenvironment is composed of a complex, interconnected network of protagonists, including soluble factors such as cytokines, extracellular matrix components, interacting with fibroblasts, endothelial cells, immune cells and various
Heymann, D. +4 more
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Histamine and Histamine H4 Receptor Promotes Osteoclastogenesis in Rheumatoid Arthritis. [PDF]
, 2017 Histamine H4 receptor (H4R) has immune-modulatory and chemotaxic effects in various immune cells. This study aimed to determine the osteoclastogenic role of H4R in rheumatoid arthritis (RA).
Firestein, Gary S +5 more
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Modelling Attitude as a Delighter in Supply Chains: A Kano-Based Perspective
LogisticsBackground: Global supply chains operate in increasingly volatile and technology-intensive environments shaped by digital transformation and artificial intelligence integration. While prior research has emphasized structural and technological enablers of
Andrea Rankl, Peter Nemeth
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