Results 21 to 30 of about 88,034 (350)

Nanotechnology-Boosted Biomaterials for Osteoarthritis Treatment: Current Status and Future Perspectives

open access: yesInternational Journal of Nanomedicine, 2023
Lin Liu, Haifeng Tang, Yanjun Wang Department of Emergency, Honghui Hospital of Xi’an Jiaotong University, Xi’an, 710054, People’s Republic of ChinaCorrespondence: Yanjun Wang; Haifeng Tang, Department of Emergency, Honghui Hospital of Xi’an Jiaotong ...
Liu L, Tang H, Wang Y
doaj  

Serum fetuin-A and RANKL levels in patients with early stage breast cancer [PDF]

open access: yesJournal of Medical Biochemistry, 2023
Background: Breast cancer (BC) is the primary cause of mortality due to cancer in females around the world. Fetuin-A is known to increase metastases over signals and peroxisomes related with growing. Receptor activator of nuclear factor-kB ligand (RANKL)
Afsar Cigdem Usul   +7 more
doaj  

Assessment of Salivary Levels of the RANKL and RANK in Patients with Healthy Gingiva on Reduced Periodontium Versus Periodontitis: An Analytical Cross-Sectional Study

open access: yesDental Hypotheses, 2023
Introduction: We aimed to compare the changes in the two salivary biomarkers, RANKL and RANK, among patients with healthy gingiva on reduced periodontium versus generalized periodontitis stages II and III.
Shurooq Abdulkareem Muhssin   +1 more
doaj   +1 more source

SNX10 gene mutation leading to osteopetrosis with dysfunctional osteoclasts [PDF]

open access: yes, 2017
Acknowledgements We sincerely thank the patients and family members who participated in this study. We would also like to thank Stefan Esher, Umeå University, for help with genealogy, and Anna Westerlund for excellent technical assistance.
Ameur, Adam   +15 more
core   +1 more source

Targeting RANKL in metastasis [PDF]

open access: yesBoneKEy Reports, 2014
Acting through its cognate receptor, receptor activator of nuclear factor-κB (RANK), RANK ligand (RANKL) is an essential mediator of osteoclast function and survival. Preclinical data have now firmly established that blockade of tumor-induced osteoclastogenesis by RANKL inhibition will not only protect against bone destruction but will also inhibit the
Dougall, W.C.   +2 more
openaire   +3 more sources

The role of denosumab in the complex treatment of giant cell tumor of the spine: reducing of local recurrence rate, surgery time and blood loss

open access: yesХирургия позвоночника, 2021
Objective. To assess the effect of the combined treatment method including preoperative denosumab therapy on the results of treatment of patients with giant cell tumors of the spine. Material and Methods.
Anastasia A. Tararykova   +6 more
doaj   +1 more source

Aplidin (plitidepsin) is a novel anti-myeloma agent with potent anti-resorptive activity mediated by direct effects on osteoclasts [PDF]

open access: yes, 2019
Despite recent progress in its treatment, Multiple Myeloma (MM) remains incurable and its associated bone disease persists even after complete remission.
Atkinson, Emily G.   +7 more
core   +1 more source

The RANKL-RANK Story [PDF]

open access: yesGerontology, 2015
Receptor activator of nuclear factor κB (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL
Vanja, Nagy, Josef M, Penninger
openaire   +2 more sources

RANKL inhibits activation of hepatic stellate cells during hepatic fibrosis in mice

open access: yes陆军军医大学学报, 2023
Objective To explore the biological role of receptor activator of nuclear factor kappa-B ligand (RANKL) in the activation of hepatic stellate cells (HSCs) and the process of hepatic fibrosis.
ZHOU Lijia   +4 more
doaj   +1 more source

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