Results 61 to 70 of about 105,143 (344)
Targeting the RANKL/RANK/OPG Axis for Cancer Therapy
Frontiers in Oncology, 2020 RANKL and RANK are expressed in different cell types and tissues throughout the body. They were originally described for their essential roles in bone remodeling and the immune system but have subsequently been shown to provide essential signals from ...
Jie Ming +2 more
semanticscholar +1 more source
3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research
Advanced Functional Materials, EarlyView.A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram +5 more
wiley +1 more source
Advanced Functional Materials, EarlyView.This comprehensive review explores therapeutic titanium implants designed to enhance integration and provide superior antibacterial efficacy. It is focused on anodized titanium implants with titania nanotubes (TNTs) loaded with nanoparticles (NPs) for local therapeutic release, enhancing bioactivity and bactericidal functions.
Divya Chopra +5 more
wiley +1 more source
Journal of Inflammation Research, 2023 Mingzhe Feng,1,* Lin Liu,2,* Jiang Wang,1 Jialang Zhang,1 Zechao Qu,1 Yanjun Wang,3 Baorong He1 1Department of Spine Surgery, Honghui Hospital, School of Medicine, Xi’an Jiao Tong University, Xi’an, People’s Republic of China; 2Department of ...
Feng M +6 more
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Detection Of Rankl Positive Cells in Gingival Tissue in Healthy & Chronic Periodontal Disease Patients -A Comparative Study [PDF]
Journal of Clinical and Diagnostic Research, 2014 Aim & Objective: The receptor activator of NF-kappa B ligand (RANKL) and its decoy receptor, osteoprotegerin (OPG), are the important proteins implicated in osteoclastogenesis.
J. BHUVANESWARRI +2 more
doaj +1 more source
General analysis of mathematical models for bone remodeling
, 2010 Bone remodeling is regulated by pathways controlling the interplay of osteoblasts and osteoclasts. In this work, we apply the method of generalized modelling to systematically analyse a large class of models of bone remodeling.
Gross, Thilo +3 more
core +1 more source
RANKL/RANK/OPG system beyond bone remodeling: involvement in breast cancer and clinical perspectives
Journal of experimental & clinical cancer research : CR, 2019 RANKL/RANK/OPG system consists of three essential signaling molecules: i) the receptor activator of nuclear factor (NF)-kB-ligand (RANKL), ii) the receptor activator of NF-kB (RANK), and iii) the soluble decoy receptor osteoprotegerin (OPG).
M. Infante +5 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex +4 more
wiley +1 more source
Internal inflammatory root resorption in permanent teeth
Эндодонтия Today, 2020 Internal inflammatory root resorption is a rare find in everyday dental practice. Also, it is known to be an accident discovery. Analysis of publications of domestic and foreign periodicals and of biochemistry, histology, microbiology textbooks has ...
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Oroxin B Attenuates Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Formation and Activity
Drug Design, Development and Therapy, 2021 Jun-ming Huang, Chen-zhong Wang, Shun-yi Lu, Zhe Wang, Zuo-qin Yan Department of Orthopaedics, Zhongshan Hospital, Fudan University, Shanghai, 200032, People’s Republic of ChinaCorrespondence: Zuo-qin Yan 180 Feng Lin Road, Xuhui District, Shanghai ...
Huang JM, Wang CZ, Lu SY, Wang Z, Yan ZQ
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