Results 71 to 80 of about 105,143 (344)

Modeling of the kinetics of vitamin D$_3$ in osteoblastic cells

open access: yesMathematical Biosciences and Engineering, 2012
A one-dimensional model for the transport of vitamin D$_3$ in anosteoblast cell is proposed, from its entry through the membraneto its activation of RANKL synthesis in the nucleus.
Robert P. Gilbert   +2 more
doaj   +1 more source

Association of NFKB1, NKX2-5, GATA4 and RANKL gene polymorphisms with sporadic congenital heart disease in Greek patients

open access: yesBalkan Journal of Medical Genetics, 2021
Congenital heart disease (CHD) is a group of structural defects of the heart and the great vessels, and one of the leading causes of death among infants and young adults.
Aidinidou L   +6 more
doaj   +1 more source

The unbearable lightness of bone marrow homeostasis [PDF]

open access: yes, 2015
The anatomical and functional dimensions of bone marrow topography have been at the forefront of modern bone and immunological research for many years and remain a source of complexity and perplexity due to the multitude of microhabitats within this ...
AGAS, DIMITRIOS   +3 more
core   +1 more source

Si Inhibited Osteoclastogenesis: The Role of Fe and the Fenton Reaction

open access: yesAdvanced Healthcare Materials, EarlyView.
Silicate (Si) inhibition of osteoclastogenesis, is mediated by Fe. Si chemical interactions with Fe inhibit the Fenton reaction and intercellular ROS availability. This reduction in ROS availability inhibits osteoclastogenesis. The addition of Fe, in Si‐inhibited osteoclast cultures, restores the Fenton reaction, and osteoclastogenesis.
Yutong Li   +7 more
wiley   +1 more source

Polylactic/polyglycolic acid copolymer is a good carrier for BMP-2 on bone regeneration?

open access: yesBioscience Journal, 2017
The aim of this work was to evaluate the role of polylactic /polyglycolic acid copolymer as carrier for BMP-2 on bone regeneration in rat calvarium. Forty five adult male rats underwent 5-mm critical defects in bone calvaria to be divided into three ...
Alexandre Ladeira Veloso dos Anjos   +7 more
doaj   +1 more source

Osteoprotegerin reduces osteoclast resorption activity without affecting osteogenesis on nanoparticulate mineralized collagen scaffolds. [PDF]

open access: yes, 2019
The instructive capabilities of extracellular matrix-inspired materials for osteoprogenitor differentiation have sparked interest in understanding modulation of other cell types within the bone regenerative microenvironment.
Bischoff, David   +11 more
core  

Vibration‐Mediated Recovery of Irradiated Osteocytes and Their Regulatory Role in Breast Cancer Bone Metastasis

open access: yesAdvanced Healthcare Materials, EarlyView.
Radiotherapy damages bone and disrupts osteocyte function, yet mechanically mediated protection remains largely unexplored. This study demonstrates that low‐magnitude, high‐frequency (LMHF) vibration mitigates irradiated osteocyte apoptosis, restores their ability to regulate breast cancer extravasation, and acts synergistically with radiotherapy to ...
Xin Song   +7 more
wiley   +1 more source

Denosumab treatment in patients with different courses of osteoporosis

open access: yesОстеопороз и остеопатии, 2017
We present three clinical cases of successful osteoporosis treatment with denosumab in patients with different courses of osteoporosis: postmenopausal with bisphosphonates ineffectiveness, osteoporosis of mixed etiology in patient on thyroid stimulating ...
Liudmila Ya. Rozhinskaya   +4 more
doaj   +1 more source

The Effects of Exercise Intensity Difference on Bone Metabolic Markers and Cytokines of the RANKL/RANK/OPG System in Korean Osteopenia Elderly Women [PDF]

open access: yes운동과학, 2017
PURPOSE Regular exercise augments the bone mineral density in postmenopausal elderly women. However, its acute effects by different intensities on bone metabolic markers and cytokines of the RANKL/RANK/OPG system have not been determined.
Chang-Sun Kim   +6 more
doaj   +1 more source

1, 25-dihydroxy vitamin D3 alleviates collagen-induced arthritis via regulating Th17/Treg ratio and RANKL/OPG axis

open access: yes陆军军医大学学报, 2023
Objective To investigate the mechanisms of 1, 25(OH)2D3 on joint inflammation and bone destruction in a mouse model of collagen-induced arthritis (CIA). Methods Thirty DBA/1J mice were equally allocated into control, CIA and intervention (VD) groups. The
QI Kun, LIU Yun, TANG Tao, LUO Xiwen
doaj   +1 more source

Home - About - Disclaimer - Privacy