Spike protein D614G and RdRp P323L: the SARS-CoV-2 mutations associated with severity of COVID-19
Genomics & Informatics, 2020 The severity of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), greatly varies from patient to patient.
S. Biswas, S. R. Mudi
semanticscholar +1 more source
Real-time PCR Ct value in SARS-CoV-2 detection: RdRp or N gene?
Infection, 2021 Due to the rapid spread and increasing number of coronavirus disease 19 (COVID-19) cases caused by Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), simple, rapid, sensitive, and specific technique is necessary for routine detection of virus ...
Hamidreza Abbasi +4 more
semanticscholar +1 more source
Macromolecular Rapid Communications, EarlyView.Arsonic acid containing diblock copolymers are developed to incorporate arsonic acid moieties for surface anchoring to IONPs, along with water soluble PEG blocks to impart colloidal stability in aqueous environments. The resulting polymer‐coated IONPs are evaluated for stability in physiological media and cytocompatibility.
Nhu Thao Huynh +10 more
wiley +1 more source
Identification, Molecular Characterization, and Biology of a Novel Quadrivirus Infecting the Phytopathogenic Fungus Leptosphaeria biglobosa. [PDF]
, 2018 Here we report the molecular characterisation of a novel dsRNA virus isolated from the filamentous, plant pathogenic fungus Leptosphaeria biglobosa and known to cause significant alterations to fungal pigmentation and growth and to result in ...
Coutts, Robert +3 more
core +2 more sources
Frontiers in Molecular Biosciences, 2021 The COVID-19 pandemic has now strengthened its hold on human health and coronavirus’ lethal existence does not seem to be going away soon. In this regard, the optimization of reported information for understanding the mechanistic insights that facilitate
Mitul Srivastava +3 more
semanticscholar +1 more source
Iflaviruses in arthropods: when small is mighty
Insect Science, EarlyView.Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia +3 more
wiley +1 more source
Cu(0)-RDRP of methacrylates in DMSO: importance of the initiator [PDF]
Polymer Chemistry, 2018 The controlled radical polymerization of methacrylates via Cu(0)-mediated RDRP is challenging in comparison to acrylates with most reports illustrating higher dispersities, lower monomer conversions and poorer end group fidelity relative to the acrylic analogues.
Glen R. Jones +6 more
openaire +3 more sources
Living and controlled reversible‐activation polymerization (
, 2022 Graeme Moad
openalex +1 more source
Rituximab-Containing Treatment Regimens May Imply a Long-Term Risk for Difficult-To-Treat Chronic Hepatitis E [PDF]
, 2020 Hepatitis E virus (HEV) infection is an emerging disease in industrialized countries which is usually characterized by a self-limited course. However, there is an increased risk of HEV persistence in immunocompromised risk populations, comprising ...
Biedermann, Paula +7 more
core +1 more source
Targeting Genome Maintenance Defects of Cancers Using Chain‐Terminating Nucleoside Analogs
Cancer Science, EarlyView.Nucleoside analogs interfere with DNA replication either by their chain‐terminating properties or by serving as DNA damage on the template. The genome maintenance pathways required to maintain cellular tolerance to each nucleoside analog vary depending on the drug.
Ryotaro Kawasumi +2 more
wiley +1 more source