Results 41 to 50 of about 46,334 (221)
Importance of Zika Virus NS5 Protein for Viral Replication
Pathogens, 2019 Zika virus is the latest addition to an ever-growing list of arboviruses that are causing outbreaks with serious consequences. A few mild cases were recorded between 1960 and 1980 until the first major outbreak in 2007 on Yap Island. This was followed by
Hesham Elshahawi +2 more
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Viruses, 2023 Background: As long as COVID-19 endures, viral surface proteins will keep changing and new viral strains will emerge, rendering prior vaccines and treatments decreasingly effective.
Brittany A. Comunale +5 more
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Conformational Changes in Motif D of RdRPs as Fidelity Determinant [PDF]
Structure, 2012 RNA-dependent RNA polymerases (RdRPs) are the central players in both transcription and viral genome replication. Using NMR spectroscopy, Yang and colleagues (in this issue of Structure) show that the conformational changes in the structural motif D of poliovirus RdRP correlate with the nature of the bound nucleotide (correct versus incorrect), with a ...
Verdaguer, Nuria, Ferrer-Orta, Cristina
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A novel mechanism underlying the innate immune response induction upon viral-dependent replication of host cell mRNA: A mistake of +sRNA viruses' replicases [PDF]
, 2017 Viruses are lifeless particles designed for setting virus-host interactome assuring a new generation of virions for dissemination. This interactome generates a pressure on host organisms evolving mechanisms to neutralize viral infection, which places the
Colombo, Maria Isabel +1 more
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Meta-analysis of honey bee neurogenomic response links deformed wing virus type A to precocious behavioral maturation [PDF]
, 2020 Crop pollination by the western honey bee Apis mellifera is vital to agriculture but threatened by alarmingly high levels of colony mortality, especially in Europe and North America.
Ahmed, Amy Cash +7 more
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Biophysical Chemistry, 2021 Despite all the efforts to treat COVID-19, no particular cure has been found for this virus. Since developing antiviral drugs is a time-consuming process, the most effective approach is to evaluate the approved and under investigation drugs using in silico methods. Among the different targets within the virus structure, as a vital component in the life
Poustforoosh, Alireza +5 more
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RNA-Dependent RNA Polymerase from Heterobasidion RNA Virus 6 Is an Active Replicase In Vitro
Viruses, 2021 Heterobasidion RNA virus 6 (HetRV6) is a double-stranded (ds)RNA mycovirus and a member of the recently established genus Orthocurvulavirus within the family Orthocurvulaviridae.
Alesia A. Levanova +3 more
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RdRp-based sensitive taxonomic classification of RNA viruses for metagenomic data [PDF]
Briefings in Bioinformatics, 2022 Abstract With advances in library construction protocols and next-generation sequencing technologies, viral metagenomic sequencing has become the major source for novel virus discovery. Conducting taxonomic classification for metagenomic data is an important means to characterize the viral composition in the underlying samples.
Tang, Xubo, Shang, Jiayu, Sun, Yanni
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Infection and Drug Resistance, 2021 Endriyas Kelta Wabalo, Abebe Dukessa Dubiwak, Mengistu Welde Senbetu, Tariku Sime Gizaw Department of Biomedical Sciences, Faculty of Medical Sciences, Institute of Health, Jimma University, Jimma, EthiopiaCorrespondence: Endriyas Kelta WabaloDepartment ...
Kelta Wabalo E +3 more
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Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ, 2023 The Covid-19 pandemic has emerged as a global health crisis, with no definitive end in sight. In this study, molecular docking was employed to screen compounds derived from Eclipta prostrata for their potential inhibitory effects on the RNA-dependent RNA
Hồ Thiên Hoàng +3 more
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