Results 31 to 40 of about 36,268 (188)

Interaction network of hNV and mNV-RdRp/6 complex.

, 2014
A) Fragment of 6 (carbon atoms in yellow) bound to hNV-RdRp in cartoon (magenta). All the amino acids involved in interaction with the inhibitor molecule are shown in sticks (carbon atoms in magenta).
Martino Bolognesi (104753), Jih Ru Hwu (534220), Mario Milani (119980), Jacques Rohayem (534219), Margherita Pezzullo (179177), Shwu-Chen Tsay (534216), Yi-Jin Tsai (534218), Eloise Mastrangelo (120000), Romina Croci (534214), Delia Tarantino (534215), Radhakrishnan Sureshbabu (534217)   +10 more
core   +1 more source

Gn recruits RdRp.

, 2013
A. BSR-T7/5 cells were transfected with pRdRp or pGn, and the proteins were visualized with anti-RdRp and anti-Gn, respectively (green channel). Cellular resident Golgi apparatus proteins, GS-28 or β-COP were also labeled (red channel).
Dorothy R. Sorenson (354497), Mary E. Piper (354496), Sonja R. Gerrard (354498)   +2 more
core   +1 more source

Mutations in RNA‐dependent RNA polymerase could be major cause of high pandemic potential of SARS‐CoV‐2: An in‐silico study

Indonesian Journal of Biotechnology
Human coronaviruses (HCoVs) are responsible for mild common cold to severe pneumonia‐like symptoms in infected individuals. The first HCoV was HCoV‐229E, discovered in 1962 in the US, which causes moderate symptoms.
Bhawna Sharma, Bennet Angel, Annette Angel, Vinod Joshi, Shareef Mohammed Buvvaji, Neha Singh, Khushbu Kumari, Aarya Chitransh, Poorna Khaneja, Devendra Kumar   +9 more
doaj   +1 more source

RdRp-scan: A bioinformatic resource to identify and annotate divergent RNA viruses in metagenomic sequence data

, 2022
Despite a rapid expansion in the number of documented viruses following the advent of metagenomic sequencing, the identification and annotation of highly divergent RNA viruses remain challenging, particularly from poorly characterized hosts and ...
HOLMES, Edward, Jan P Buchmann, BUCHMANN, Jan, Sadiq, Sabrina, Buchmann, Jan P, Holmes, Edward C, Sabrina Sadiq, Charon, Justine, Justine Charon, Edward C Holmes   +9 more
core   +1 more source

Heterogeneous catalysis in photo-RDRP : towards green polymer manufacturing [PDF]

, 2021
The rapid development of reversible deactivation radical polymerization (RDRP) enables the preparation of well-defined polymers with diverse topological architectures and functionalities.
Chu, Yingying
core   +1 more source

Evaluation of the Antiviral Characteristics of Tetragonula sapiens Propolis from Indonesia Using In Vitro and In Silico Methods

International Journal of Technology
The previous outbreaks of syndrome coronavirus 2 (SARS-CoV-2) are indications of the need for effective antiviral agents to mitigate disease severity and future outbreaks. In this context, natural products such as propolis have gained attention for their
Safira Candra Asih, Mohammad Nasikin, Jim-Tong Horng, Hui-Ping Tsai, Shan-Ko Tsai, Cheng-Hsun Chiu, Diah Kartika Pratami, Abdul Mun’im, Muhamad Sahlan   +8 more
doaj   +1 more source

Number of loci down-regulated at sRNA level in rdrp-1^- and rdrp-2^- mutants^a.

, 2015
aTotal number of loci (with normalized abundance of more than 50 reads per million) showing a fourfold or higher reduction in the rdrp- mutant strains compared to the wild type.bLoci that show the reduction only in the rdrp-1- or rdrp-2- mutants are ...
Santiago Torres-Martínez (287240), Francisco E. Nicolás (287239), Silvia Calo (392648), Ana Vila (436509), Victoriano Garre (721176), Trung Anh Trieu (721175), Simon Moxon (5837), Tamas Dalmay (251047), Rosa M. Ruiz-Vázquez (5651434)   +8 more
core   +1 more source

A Structure-Function Diversity Survey of the RNA-Dependent RNA Polymerases From the Positive-Strand RNA Viruses

Frontiers in Microbiology, 2019
The RNA-dependent RNA polymerases (RdRPs) encoded by the RNA viruses are a unique class of nucleic acid polymerases. Each viral RdRP contains a 500–600 residue catalytic module with palm, fingers, and thumb domains forming an encircled human right hand ...
Hengxia Jia, Hengxia Jia, Peng Gong
doaj   +1 more source

Natural plant products as potential inhibitors of RNA dependent RNA polymerase of Severe Acute Respiratory Syndrome Coronavirus-2.

PLoS ONE, 2021
Drug repurposing studies targeting inhibition of RNA dependent RNA polymerase (RdRP) of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) have exhibited the potential effect of small molecules.
Shruti Koulgi, Vinod Jani, Mallikarjunachari Uppuladinne V N, Uddhavesh Sonavane, Rajendra Joshi   +4 more
doaj   +1 more source

RNAi in the Rhizarian Phytopathogen Plasmodiophora brassicae: The Causal Agent of Clubroot Disease in Cruciferous Crops

Advanced Science, EarlyView.
This study uncovers an unusual RNAi pathway in the rhizarian pathogen Plasmodiophora brassicae. In the absence of Dicer, a Drosha‐like RNase III protein supports the biogenesis of predominant 21‐nt small RNAs, and two Argonaute proteins mediate small RNA‐guided silencing.
Xiong Zhang, Yupo Wu, Jiachang Hou, Lixia Gao, Longqi Pan, Cuicui Shen, Chuanji Zhao, Feng Gao, Yi Zhang, Li Ren, Xiaoping Fang, Xiaoling Dun, Shengyi Liu, Lijiang Liu   +13 more
wiley   +1 more source