Results 51 to 60 of about 250,441 (257)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

What predicts word reading in Arabic?

open access: yesFrontiers in Psychology, 2023
Efficient and accurate word reading ability is critical for later reading success. As such, it is important to understand the component skills that underlie strong word reading ability.
Elsayed E. A. Hassanein   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Researches on The Accuracy of the DCMT Circle Reading System [PDF]

open access: yesSymposium - International Astronomical Union, 1993
The declinations of stars are determined by the circle micrometers on the meridian circle. The determined accuracy of declinations depends on the systematic accuracy of the micrometers. The DCMT (Danish Chinese Meridian Telescope) adopts photoelectric scanning micrometers as the circle reading system.
openaire   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

The Impact of Diplopia on Reading

open access: yesBritish and Irish Orthoptic Journal, 2019
Aim: To compare the effect of induced vertical diplopia (small and large separation) on reading speed and accuracy. Method: The Radner Reading Chart (RRC) was used to measure reading speed (correct words per minute (wpm)) and accuracy (percentage ...
Beckie Lijka   +2 more
doaj   +1 more source

Fluency Training for Struggling Readers: Examining the Effects of a Tier-2 Intervention in Third Graders

open access: yesEducation Sciences, 2023
Tier-2 reading fluency interventions are specifically tailored for struggling readers, addressing their unique needs. The aim of this study was to examine the impact of a Tier-2 reading fluency intervention on reading capabilities and motivation among ...
Joana Cruz   +4 more
doaj   +1 more source

Using quality scores and longer reads improves accuracy of Solexa read mapping [PDF]

open access: yesBMC Bioinformatics, 2008
Abstract Background Second-generation sequencing has the potential to revolutionize genomics and impact all areas of biomedical science. New technologies will make re-sequencing widely available for such applications as identifying genome variations or interrogating the oligonucleotide content of a large sample (e.g ...
Andrew D. Smith   +2 more
openaire   +3 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

LSCplus: a fast solution for improving long read accuracy by short read alignment [PDF]

open access: yesBMC Bioinformatics, 2016
Abstract Background The single molecule, real time (SMRT) sequencing technology of Pacific Biosciences enables the acquisition of transcripts from end to end due to its ability to produce extraordinarily long reads (>10 kb). This new method of transcriptome sequencing has been applied to several projects on humans and
Ruifeng Hu 0002, Guibo Sun, Xiaobo Sun
openaire   +2 more sources

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