Results 121 to 130 of about 20,909,028 (154)

Human PrP E219K: a new and promising substrate for robust RT-QuIC amplification of human prions with potential for strain discrimination

Microbiology Spectrum
Mammalian prion diseases are fatal neurodegenerative disorders caused by the conformational conversion of the host-encoded prion protein (PrP) into a pathogenic, misfolded isoform, known as PrPSc.
A. Marín-Moreno, F. Reine, F. Jaffrézic, L. Herzog, H. Rezaei, I. Quadrio, S. Haïk, V. Béringue, D. Martin   +8 more
doaj   +1 more source

ePoster

European Journal of Neurology, Volume 33, Issue S1, June 2026.
wiley   +1 more source

A Real Time Quaking Induced Conversion (RT-QuIC) Assay for Detection of Misfolded Insulin Protein

Abstract Protein misfolding plays a critical role in aging and disease, yet the involvement of specific proteins in metabolic dysfunction is still poorly understood. Here, we report studies on the development of a Real-time Quaking-Induced Conversion (RT-QuIC) assay to detect misfolded insulin, a peptide hormone required for blood ...
Jessica M. Alderiso, Rafael Hernandez LaTorre, Trisha M. Cox, Matthew G. DiGiovanni, Keileigh Fulbright, Brenda F. Canine   +5 more
openaire   +1 more source

Diagnostic Value of the CSF α-Synuclein Real-Time Quaking-Induced Conversion Assay at the Prodromal MCI Stage of Dementia With Lewy Bodies. [PDF]

Neurology, 2021
Rossi M, Baiardi S, Teunissen CE, Quadalti C, van de Beek M, Mammana A, Stanzani-Maserati M, Van der Flier WM, Sambati L, Zenesini C, Caughey B, Capellari S, Lemstra AW, Parchi P.   +13 more
europepmc   +1 more source

Real-Time Quaking-Induced Conversion Detection of PrP^Sc in Fecal Samples From Chronic Wasting Disease Infected White-Tailed Deer Using Bank Vole Substrate. [PDF]

Front Vet Sci, 2021
Hwang S, Greenlee JJ, Nicholson EM.
europepmc   +1 more source

Detection by real-time quaking-induced conversion (RT-QuIC), ELISA, and IHC of chronic wasting disease prion in lymph nodes from Pennsylvania white-tailed deer with specific PRNP genotypes. [PDF]

J Vet Diagn Invest, 2021
Tewari D, Steward D, Fasnacht M, Livengood J.   +3 more
europepmc   +1 more source

MDARTS: A Multiprocessor Database Architecture for Real-Time Systems

, 2007
Some of the advanced real-time systems being proposed, such as the Next Generation Workstation/Machine Controller (NGC) for automated factories, require a built-in database to support concurrent data access and provide well-defined interfaces between ...
Real-Time Computing Laboratory
core  

Real-Time Quaking-Induced Conversion Assay Applied to the Italian Chronic Wasting Disease Monitoring Plan: Comparison of Classical and Innovative Diagnostic Methods. [PDF]

Pathogens
Mazza M, Favole A, Campia V, Iulini B, Nonno R, Ligios C, Pintus D, Peletto S, Casalone C, Corona C, Bozzetta E, Acutis PL.   +11 more
europepmc   +1 more source

Comparison of the detection of the chronic wasting disease prion by real-time quaking-induced conversion (rtQuIC) and silica nanoparticle-rtQuIC (nano-rtQuIC) assays in retropharyngeal lymph nodes of white-tailed deer, mule deer, and Rocky Mountain elk. [PDF]

J Vet Diagn Invest
Ralston BA, Jennings J, Allen SE.
europepmc   +1 more source

Induced Seismicity Task Force Submits Seismic Action Plan To Governor Sam Brownback [2014]

, 2014
October 1 ...
Kansas Induced Seismicity State Task Force.
core