Results 101 to 110 of about 10,380 (154)

Creutzfeldt-Jakob Disease – A Series of Four Clinical Cases

Acta Medica Bulgarica
Creutzfeldt-Jakob Disease (CJD) is a rare, progressive, and fatal degenerative brain disorder caused by prion proteins. The diagnosis of the disease is based on established criteria and biomarkers – cerebrospinal fluid analysis, real-time quaking induced
Karameshev A., Yoshinov B., Dimova P., Tanova R., Penkov M., Kochmalarski B., Mihaylova K., Stoilova D., Shotekov P.   +8 more
doaj   +1 more source

Determination of prion proteins in the diagnosis of Creutzfeldt-Jakob disease using RT-QuIC: A case report from northeastern Colombia

Biomédica: revista del Instituto Nacional de Salud
Creutzfeldt-Jakob disease is a rare neurodegenerative disease caused by prions. We present the case of a woman in the seventh decade of life with rapidly progressive dementia and myoclonus.
Jairo Lizarazo, Aixa Xiomara Vargas, Rafael Olarte, David Andrés Lizarazo   +3 more
doaj   +1 more source

Lumped time-delay compensation scheme for coding synchronization in the nonlinear spectral quantization-based all-optical analog-to-digital conversion

, 2013
In this paper, we propose a novel lumped time-delay compensation scheme for the all-optical analog-to-digital conversion based on soliton self-frequency shift and optical interconnection techniques.
Y, Chongxiu, Yu, Chongxiu, Li, Sha, Khang, Zhe, Yuan, Jinhui, Farrell, Gerald, Wang, Tao, Sang, Xinzhu, Kang, Zhe, Wu, Qiang   +9 more
core   +1 more source

Adult‐Onset Subacute Sclerosing Panencephalitis Presenting With Subacute Cognitive Deficits

Annals of Clinical and Translational Neurology, Volume 13, Issue 4, Page 845-849, April 2026.
ABSTRACT We describe the case of a 41‐year‐old man diagnosed with adult‐onset subacute sclerosing panencephalitis (SSPE). The patient presented with subacute progressive cognitive deficits and a neuropsychological profile indicating predominant frontoparietal dysfunction. MRI showed only mild parietal‐predominant cerebral atrophy.
Dennis Yeow, Nicola McKern, Vincent Oxenham, Kate Ahmad, Omar Ahmad   +4 more
wiley   +1 more source

Tracking tau and cellular responses in human iPSC‐microglia: from uptake to seedable secretion, including in extracellular vesicles

Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract INTRODUCTION Microglia have been implicated in the templated spread of tau aggregates in tauopathies through mouse studies. However, it is unclear whether these findings translate to human disease. METHODS We challenged human induced pluripotent stem cell (iPSC)‐derived microglia‐like‐cells (iMGL) with monomeric and fibrillar recombinant tau ...
Maria Kreger Karabova, Anna del Ser‐Badia, Anne Hedegaard, Sam J. Washer, Zeynep Baykam, Darragh P. O'Brien, Iolanda Vendrell, Svenja S. Hester, Roman Fischer, Errin Johnson, Charlotte E. Melia, Teige R. S. Matthews‐Palmer, Rishi Matadeen, Alessia Santambrogio, Michael A. Metrick II, Michele Vendruscolo, Sophie Keeling, Kimberly Ai Xian Cheam, William A. McEwan, Kenneth S. Kosik, Theresa A. Day, William S. James, Sally A. Cowley   +22 more
wiley   +1 more source

Prion disease blood test using immunoprecipitation and improved quaking-induced conversion

, 2011
A key challenge in managing transmissible spongiform encephalopathies (TSEs) or prion diseases in medicine, agriculture, and wildlife biology is the development of practical tests for prions that are at or below infectious levels.
Caughey B., Raeber AJ, Wilham JM, ORRU', CHRISTINA DORIANA, Raymond LD, Kuhn F, Schroeder B   +6 more
core   +2 more sources

The Phenotypic Spectrum of Sporadic Creutzfeldt‐Jakob Disease Cortical Subtype

Annals of Neurology, Volume 99, Issue 4, Page 883-896, April 2026.
Objective The objective of this study was to characterize the phenotypic spectrum of the rare sporadic Creutzfeldt‐Jakob disease cortical subtype (sCJDMM/MV2C) in a large multicentric autopsy cohort. Methods We evaluated clinical histories, biofluid markers, brain diffusion‐weighted (DW)‐magnetic resonance imaging (MRI), and electroencephalogram (EEG ...
Simone Baiardi, Claudia Marina Vargiu, Brian S. Appleby, Marcelo Barria, Giuseppe Mario Bentivenga, Ignazio Calì, Benedetta Carlà, Mark Cohen, Armin Giese, Jochen Herms, Aino‐Minerva Kortelainen, Anna Ladogana, Angela Mammana, Diane Ritchie, Otto Windl, Sabina Capellari, Piero Parchi   +16 more
wiley   +1 more source

Detection of chronic wasting disease prions in soil at an illegal white-tailed deer carcass disposal site

Prion
Chronic wasting disease (CWD) is a contagious prion disorder affecting cervids such as deer, elk, caribou, and moose, causing progressive and severe neurological degeneration followed by eventual death.
Madeline K. Grunklee, Stuart S. Lichtenberg, Nicole A. Lurndahl, Marc D. Schwabenlander, Diana L. Karwan, E. Anu Li, Jason C. Bartz, Qi Yuan, Peter A. Larsen, Tiffany M. Wolf   +9 more
doaj   +1 more source

Real-Time Pyruvate Chemical Conversion Monitoring Enabled by PHIP

, 2023
In recent years, parahydrogen-induced polarization side arm hydrogenation (PHIP-SAH) has been applied to hyperpolarize [1-13C]pyruvate and map its metabolic conversion to [1-13C]lactate in cancer cells.
Salvatore Mamone (1868716), Anil P. Jagtap (4434049), Yonghong Ding (3578078), Gabriele Stevanato (1357617), Sergey Korchak (12015731), Stefan Glöggler (4134937)   +5 more
core   +1 more source

Gerstmann-Sträussler- Scheinker Disease: A Case Report

Journal of the Korean Society of Radiology, 2023
Gerstmann-Sträussler-Scheinker (GSS) disease is a rare hereditary prion disease which is clinically characterized by a progressive cerebellar ataxia followed by cognitive impairment.
Minji Shin, Donghyun Kim, Young Jin Heo, Jin Wook Baek, Suyoung Yun, Hae Woong Jeong   +5 more
doaj   +1 more source