Misfolded α-Synuclein in Autosomal Dominant Alzheimer's Disease. [PDF]
We analyzed Lewy body (LB) pathology in 18 autosomal dominant Alzheimer's disease (ADAD) brains via immunohistochemistry. Real-time quaking induced conversion was used to detect misfolded α-synuclein (α-syn) in 18 living ADAD cerebrospinal fluid (CSF ...
Antonell A +9 more
core +1 more source
The American lobster (Homarus americanus) is harvested along the eastern seaboard of North America and forms the economic backbone of many small fishing communities in Atlantic Canada and the northeastern United States.
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Prion Seeding Activity in Plant Tissues Detected by RT-QuIC
Prion diseases such as scrapie, bovine spongiform encephalopathy (BSE), and chronic wasting disease (CWD) affect domesticated and wild herbivorous mammals. Animals afflicted with CWD, the transmissible spongiform encephalopathy of cervids (deer, elk, and
Kate Burgener +5 more
doaj +1 more source
Application of real-time quaking-induced conversion in Creutzfeldt-Jakob disease surveillance. [PDF]
Hermann P +10 more
europepmc +1 more source
Effects of constant vs. fluctuating temperatures on performance and life history of the herbivorous pest Lymantria dispar (Lepidoptera: Eribidae) [PDF]
The role of temperature variation in organismal performance is understudied, but is critically important for understanding the response of biodiversity to climate change.
Sostak, Brendan E
core +1 more source
We have evaluated the diagnostic potential of the seeding amplification assay (SAA) in detecting α-synuclein seeding activity in postmortem brain and cerebrospinal fluid (CSF) samples from patients with primary and co-pathology α-synucleinopathies ...
Soňa Baranová +4 more
doaj +1 more source
Real-time quaking-induced conversion assays for prions: Applying a sensitive but imperfect test in clinical practice. [PDF]
Jones SM +6 more
europepmc +1 more source
The ecology of Atlantic white cedar wetlands: a community profile [PDF]
This monograph on the ecology of Atlantic white cedar wetlands is one of a series of U.S. Fish and Wildlife Service profiles of important freshwater wetland ecosystems of the United States.
Brody, Michael +2 more
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Seeding activity of skin misfolded tau as a biomarker for tauopathies
Background Tauopathies are a group of age-related neurodegenerative diseases characterized by the accumulation of pathologically hyperphosphorylated tau protein in the brain, leading to prion-like aggregation and propagation.
Zerui Wang +11 more
doaj +1 more source
Modelling and mapping of exceedance of critical loads and critical levels for acidification and eutrophication in the UK 2013-2016. Final report [PDF]
This report covers the work of the original contract (2013-15) and the following one-year extension (2015-16). The overall purpose of this project was to maintain, and where appropriate update, the UK critical loads database, and to provide estimates of ...
Barrett, Gaynor +14 more
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