Results 101 to 110 of about 20,909,028 (154)

Accurate detection of pathologic α-synuclein in CSF, skin, olfactory mucosa, and urine with a uniform seeding amplification assay

Acta Neuropathologica Communications
Currently, early diagnosis of dementia with Lewy bodies (DLB) is based on clinical criteria, which is challenging due to overlapping symptoms with other neurodegenerative diseases. Seeding amplification assays, detecting minute amounts of disease causing
Remarh Bsoul, Oskar H. McWilliam, Gunhild Waldemar, Steen G. Hasselbalch, Anja H. Simonsen, Christian von Buchwald, Magne Bech, Clara H. Pinborg, Christian K. Pedersen, Sara O. Baungaard, José Lombardía, Patrick Ejlerskov, Matilde Bongianni, Erika Bronzato, Gianluigi Zanusso, Kristian S. Frederiksen, Eva L. Lund, Aušrinė Areškevičiūtė   +17 more
doaj   +1 more source

Creutzfeldt‐Jakob‐Like Presentation in Anti‐AMPAR Encephalitis

Annals of Neurology, Volume 99, Issue 6, Page 1466-1467, June 2026.
Kate Durbano, Marie Belley, Delphine Leclercq, Louis Cousyn   +3 more
wiley   +1 more source

Dynamic scheduling of parallel real-time jobs by modelling spare capabilities in heterogeneous clusters [PDF]

, 2003
In this research, a scenario is assumed where periodic real-time jobs are being run on a heterogeneous cluster of computers, and new aperiodic parallel real-time jobs' modelled by Directed Acyclic Graphs (DAG), arrive at the system dynamically.
Nudd, G. R., Stephen A. Jarvis, Nudd, Graham R., Jarvis, Stephen A.; id_orcid, He, Ligang, Daniel P. Spooner, Spooner, Daniel P., Ligang He, Jarvis, Stephen A., Graham R. Nudd   +9 more
core   +1 more source

Gerstmann-Sträussler- Scheinker Disease: A Case Report

Journal of the Korean Society of Radiology, 2023
Gerstmann-Sträussler-Scheinker (GSS) disease is a rare hereditary prion disease which is clinically characterized by a progressive cerebellar ataxia followed by cognitive impairment.
Minji Shin, Donghyun Kim, Young Jin Heo, Jin Wook Baek, Suyoung Yun, Hae Woong Jeong   +5 more
doaj   +1 more source

Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion. [PDF]

The development of technologies for the in vitro amplification of abnormal conformations of prion protein (PrP(Sc)) has generated the potential for sensitive detection of prions.
Yamaguchi, Naohiro, Nakagaki, Takehiro, Yamada, Masahito, Matsubara, Takehiro, Sano, Kazunori, Satoh, Katsuya, Fuse, Takayuki, Yamanaka, Hitoki, Mizusawa, Hidehiro, Nishida, Noriyuki, Ishibashi, Daisuke, Collins, Steven J, Atarashi, Ryuichiro, Shirabe, Susumu, Kitamoto, Tetsuyuki, Klug, Genevieve, McGlade, Amelia   +16 more
core  

Développement d’une méthode de détection des alpha-synucléinopathies par technologie RT-QuIC (Real Time-Quaking Induced Conversion)

, 2023
International audienceIntroductionLe diagnostic des α-synucléinopathies (A-syn) par la détection des formes agrégées d’alpha-synucléine semble prometteur.
Kaczorowski, Flora, Mollion, Hélène, Formaglio, Maïté, Fourier, Anthony, Verdurand, Mathieu, Quadrio, Isabelle, Desestret, Virginie   +6 more
core   +1 more source

Chronic wasting disease detection in the lymph nodes of free-ranging cervids by real time quaking-induced conversion [PDF]

, 2014
Chronic wasting disease (CWD), a transmissible spongiform encephalopathy of deer, elk and moose, is the only prion disease affecting free-ranging animals.
Galeota, Judith, Gray, Shawn, Carver, Scott, Bunting, Elizabeth, Haley, Nicholas J., Davenport, Kristen A., Dubovos, Tracy, Hoon-Hanks, Laura, LeVan, Ivy, Trindle, Bruce, Henderson, Davin M., Hoover, Edward A., Shelton, Paul   +12 more
core  

Prion disease blood test using immunoprecipitation and improved quaking-induced conversion

, 2011
A key challenge in managing transmissible spongiform encephalopathies (TSEs) or prion diseases in medicine, agriculture, and wildlife biology is the development of practical tests for prions that are at or below infectious levels.
Caughey B., Raeber AJ, Wilham JM, ORRU', CHRISTINA DORIANA, Raymond LD, Kuhn F, Schroeder B   +6 more
core   +2 more sources

Real-time Quaking-induced Conversion Analysis of Prion-like Seeding Activity of Pathological α-Synuclein

YAKUGAKU ZASSHI, 2019
Pathological α-synuclein (αSyn) has been shown to retain the ability to propagate as prions in humans and animals. However, the molecular basis underlying the prion-like properties of αSyn remains poorly understood. We examined whether brain tissues from cases of dementia with Lewy bodies (DLB), which contain serine 129 (Ser129)-phosphorylated ...
openaire   +3 more sources

APIS : a real-time message-oriented middleware [PDF]

, 2001
Includes bibliographical references.This thesis presents an investigation and evaluation of a Real-Time Message-Oriented Middleware (MOM) implementation using commercial off-the-shelf (COTS) software components.
Steyn, Manie C
core   +1 more source