Results 91 to 100 of about 4,479 (143)

Determination of prion proteins in the diagnosis of Creutzfeldt-Jakob disease using RT-QuIC: A case report from northeastern Colombia

Biomédica: revista del Instituto Nacional de Salud
Creutzfeldt-Jakob disease is a rare neurodegenerative disease caused by prions. We present the case of a woman in the seventh decade of life with rapidly progressive dementia and myoclonus.
Jairo Lizarazo, Aixa Xiomara Vargas, Rafael Olarte, David Andrés Lizarazo   +3 more
doaj   +1 more source

Upper Mantle Heterogeneity and Weak Subduction Boundaries Control Crustal Stress in the Korean Peninsula

Geophysical Research Letters, Volume 53, Issue 5, 16 March 2026.
Abstract Most earthquakes occur at plate boundaries, but some also strike within stable continental interiors. Although dominant causes of such intraplate earthquakes remain elusive, a prevailing hypothesis attributes intraplate stress and seismicity to variations in lithospheric thickness.
Sungho Lee, Chang Soo Cho, YoungHee Kim, Youngsang Kwon, Eunseo Choi   +4 more
wiley   +1 more source

Ex vivomammalian prions are formed of paired double helical prion protein fibrils [PDF]

, 2016
Mammalian prions are hypothesized to be fibrillar or amyloid forms of prion protein (PrP), but structures observed to date have not been definitively correlated with infectivity and the three-dimensional structure of infectious prions has remained ...
Clare, Daniel, Collinge, J., Gros, N., Hosszu, L.L.P., Joiner, S., Panico, Silvia, Saibil, Helen R., Sells, J., Tattum, M.H., Terry, C., Wadsworth, J.D.F., Wenborn, A.   +11 more
core   +2 more sources

Subsurface Expression of the Lambton Fault and Potential for the Basin Edge Effect in the Wellington Central Business District

New Zealand Journal of Geology and Geophysics, Volume 69, Issue 1, March 2026.
This study focuses on the subsurface structure of the Wellington basin and an assessment of the shaking potential due to the basin edge‐effect at its western margin. Seismic reflection surveys combined with gravity modelling provide data for a structural model from which to base our shaking analysis.
T. A. Stern, J. N. Louie, M. O. Newton, S. B. Thorpe‐Loversuch, A. I. Stronach, W. R. Stratford   +5 more
wiley   +1 more source

RNA Regulatory Networks: Key Hubs in the Panorama of Cancer and Emerging Therapeutic Targets

MedComm, Volume 7, Issue 3, March 2026.
RNA regulatory networks play a crucial role in the initiation and progression of cancer through various modes of RNA interactions. Notably, circulating RNAs have emerged as potential biomarkers, while targeted interventions in RNA regulatory networks facilitate precise therapeutic strategies. ABSTRACT Cancer is a global health challenge. The initiation
Xuan Yin, Zengkan Du, Shuya Jiang, Yan Liao, Changli Wang, Jiaqi Li, Haoling Zhang, Ting‐Ting Wei, Wangzheqi Zhang, Zui Zou   +9 more
wiley   +1 more source

Detection of chronic wasting disease prions in soil at an illegal white-tailed deer carcass disposal site

Prion
Chronic wasting disease (CWD) is a contagious prion disorder affecting cervids such as deer, elk, caribou, and moose, causing progressive and severe neurological degeneration followed by eventual death.
Madeline K. Grunklee, Stuart S. Lichtenberg, Nicole A. Lurndahl, Marc D. Schwabenlander, Diana L. Karwan, E. Anu Li, Jason C. Bartz, Qi Yuan, Peter A. Larsen, Tiffany M. Wolf   +9 more
doaj   +1 more source

Use of different RT-QuIC substrates for detecting CWD prions in the brain of Norwegian cervids [PDF]

, 2019
Chronic wasting disease (CWD) is a highly contagious prion disease affecting captive and free-ranging cervid populations. CWD has been detected in United States, Canada, South Korea and, most recently, in Europe (Norway, Finland and Sweden). Animals with
A Fediaevsky, A Franceschini, A Herbst, A Otero, A Selariu, AF Hill, AF Hill, AM Elder, AN Hamir, AN Hamir, B Pulford, B Race, B Race, B Race, C Duque Velasquez, C Johnson, C Kramm, C Meyerett, CD Orru, CD Orru, Christina Orrú, CJ Gibbs Jr., CJ Johnson, CJ Johnson, CJ Sigurdson, CJ Sigurdson, CK Mathiason, CP Hibler, D Keane, D Padilla, DC Guiroy, DC Guiroy, DM Henderson, DM Henderson, DM Henderson, DM Henderson, DP Keane, E Bistaffa, E McNulty, ED Belay, ES Almberg, ES Williams, ES Williams, ES Williams, ES Williams, ES Williams, FE Cohen, G Legname, GA Wilson, H Fraser, HJ Sohn, J Bian, J Peters, JC Bartz, JE Jewell, JM Wilham, Julie A. Moreno, JY Abrams, K Ball, KA Davenport, KA Davenport, KA Davenport, KA Fox, KC Gough, KI O’Rourke, KI O’Rourke, KI O’Rourke, Kurt Giles, L Cervenakova, L Luers, L Pirisinu, L Waddell, L Wik, LI McGuire, LI McGuire, LJ van Keulen, LL Wolfe, MA Barria, MA Barria, MA Wild, Marcello Rossi, MD Samuel, ME Bruce, ME Bruce, ME Bruce, MK Sandberg, ML Daus, MR Perrott, MW Miller, ND Denkers, ND Denkers, ND Denkers, Neil Mabbott, NJ Haley, NJ Haley, NJ Haley, NJ Haley, NJ Haley, NJ Haley, NJ Haley, NJ Haley, NJ Haley, NJ Haley, R Atarashi, RA Bessen, RA Bessen, RC Angers, RD Harrington, RF Marsh, RJ Monello, S Boerner, S Gilch, S Hannaoui, S Hannaoui, S Kaluz, S Manne, S Pritzkow, SB Prusiner, SB Prusiner, SB Prusiner, SE Bae, SE Saunders, SJ Moore, SJ Moore, SJ Robinson, SK Cooper, SL Benestad, TD Kurt, TD Kurt, TR John, TR Spraker, TR Spraker, TR Spraker, V Beringue, V Redaelli, YC Cheng   +135 more
core   +1 more source

Gerstmann-Sträussler- Scheinker Disease: A Case Report

Journal of the Korean Society of Radiology, 2023
Gerstmann-Sträussler-Scheinker (GSS) disease is a rare hereditary prion disease which is clinically characterized by a progressive cerebellar ataxia followed by cognitive impairment.
Minji Shin, Donghyun Kim, Young Jin Heo, Jin Wook Baek, Suyoung Yun, Hae Woong Jeong   +5 more
doaj   +1 more source

Accurate detection of pathologic α-synuclein in CSF, skin, olfactory mucosa, and urine with a uniform seeding amplification assay

Acta Neuropathologica Communications
Currently, early diagnosis of dementia with Lewy bodies (DLB) is based on clinical criteria, which is challenging due to overlapping symptoms with other neurodegenerative diseases. Seeding amplification assays, detecting minute amounts of disease causing
Remarh Bsoul, Oskar H. McWilliam, Gunhild Waldemar, Steen G. Hasselbalch, Anja H. Simonsen, Christian von Buchwald, Magne Bech, Clara H. Pinborg, Christian K. Pedersen, Sara O. Baungaard, José Lombardía, Patrick Ejlerskov, Matilde Bongianni, Erika Bronzato, Gianluigi Zanusso, Kristian S. Frederiksen, Eva L. Lund, Aušrinė Areškevičiūtė   +17 more
doaj   +1 more source

Neurofilaments in blood and CSF for diagnosis and prediction of onset in Creutzfeldt-Jakob disease [PDF]

, 2016
While cerebrospinal fluid (CSF) biomarkers for Creutzfeldt-Jakob disease (CJD) are established and partly included in the diagnostic criteria, no blood biomarkers are available.
Blennow, Kaj, Giese, Armin, Halbgebauer, Steffen, Kuhle, Jens, Oeckl, Patrick, Otto, Markus, Ruf, Viktoria, Shi, Song, Slivarichova, Dana, Steinacker, Petra, Zetterberg, Henrik   +10 more
core   +2 more sources