Results 91 to 100 of about 20,909,028 (154)
Detection of prions in skin punch biopsies of Creutzfeldt–Jakob disease patients
Annals of Clinical and Translational Neurology, 2020 Prion real‐time quaking‐induced conversion (RT‐QuIC) is an ultrasensitive assay detecting pathological aggregates of misfolded prion protein in biospecimens.
Angela Mammana +7 more
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Journal of Geophysical Research: Solid Earth, Volume 131, Issue 6, June 2026.Abstract We investigate shear‐wave splitting of SKS and SKKS phases from teleseismic earthquakes to study the anisotropic structure of the lithosphere and upper mantle beneath the Colombian Andes. This area is shaped by complex interactions between the subducting Nazca and Caribbean plates beneath the South American plate. A recent broadband deployment
Christopher J. W. Carchedi +4 more
wiley +1 more source
Journal of General Virology, 2016 Prions have been demonstrated in body fluids and excreta using bioassay, but at levels too low for detection by conventional direct-detection assays. More rapid and sensitive detection of prions in these clinically accessible specimens would be valuable for diagnosis and investigations of transmission, environmental impact, and interventions.
Nathaniel D, Denkers +3 more
openaire +2 more sources
A new diagnostic test for Creutzfeldt-Jakob disease: Real-time quaking-induced conversion (RT-QuIC)
Canada Communicable Disease Report, 2015 Currently, definitive diagnoses of Creutzfeldt-Jakob disease (CJD) require an examination of the brains of deceased patients. In cooperation with an international consortium, Canada's National Microbiology Laboratory is performing a validation of a new test that can diagnose CJD in living patients.
D, Godal +3 more
openaire +2 more sources
Creutzfeldt-Jakob Disease – A Series of Four Clinical Cases
Acta Medica BulgaricaCreutzfeldt-Jakob Disease (CJD) is a rare, progressive, and fatal degenerative brain disorder caused by prion proteins. The diagnosis of the disease is based on established criteria and biomarkers – cerebrospinal fluid analysis, real-time quaking induced
Karameshev A. +8 more
doaj +1 more source
The FASEB Journal, Volume 40, Issue 10, 31 May 2026.Bats can sustain powered flight, but their reliance on fatty acid oxidation may limit long‐distance migration compared to birds. Using untargeted metabolomics, we analyzed blood metabolites of Nathusius' pipistrelle under controlled flight and migratory field conditions to identify fuel use.
Alesia Walker +7 more
wiley +1 more source
PrionChronic wasting disease (CWD) is a contagious prion disorder affecting cervids such as deer, elk, caribou, and moose, causing progressive and severe neurological degeneration followed by eventual death.
Madeline K. Grunklee +9 more
doaj +1 more source
Anti-Prion Screening for Acridine, Dextran, and Tannic Acid using Real Time-Quaking Induced Conversion: A Comparison with PrPSc-Infected Cell Screening. [PDF]
, 2017 Prion propagation is mediated by the structural alteration of normal prion protein (PrPC) to generate pathogenic prion protein (PrPSc). To date, compounds for the inhibition of prion propagation have mainly been screened using PrPSc-infected cells.
Yeong Seon Lee +6 more
core +1 more source
Conformational Properties of Prion Strains Can Be Transmitted to Recombinant Prion Protein Fibrils in Real-Time Quaking-Induced Conversion [PDF]
, 2014 The phenomenon of prion strains with distinct biological characteristics has been hypothesized to be involved in the structural diversity of abnormal prion protein (PrPSc).
Satoh, Katsuya +5 more
core +2 more sources
, 2014 Announcement -- Agenda -- Breakout Sessions: Questions and Responses -- An Ounce of Understanding is Worth a Pound of Cure / by Kyle E. Murray -- Induced Seismicity and the Oil and Gas Industry -- Overview of Kansas Earthquakes / Rick Miller, Shelby ...
Induced Seismicity State Task Force Meeting (2014 : Wichita, Kan.)
core +1 more source