Results 71 to 80 of about 20,909,028 (154)
Creutzfeldt-Jakob disease: recent developments [version 1; referees: 2 approved]
F1000Research, 2017 Creutzfeldt-Jakob disease (CJD) is a rare prion disorder that has been the subject of both professional and public interest following the identification of variant CJD as a zoonotic disorder.
Graeme Mackenzie, Robert Will
doaj +1 more source
Translational Neurodegeneration, 2022 Background In patients with Parkinson’s disease (PD), real-time quaking-induced conversion (RT-QuIC) detection of pathological α-synuclein (α-syn) in olfactory mucosa (OM) is not as accurate as in other α-synucleinopathies.
Matilde Bongianni +25 more
doaj +1 more source
Case report: Two clusters of Creutzfeldt–Jakob disease cases within 1 year in West Michigan
Frontiers in Neurology, 2023 BackgroundCreutzfeldt–Jakob disease (CJD) is a rare, rapidly progressive, and uniformly fatal neurodegenerative disease. The reported incidence of CJD is 1 to 2 per million people worldwide annually, with fewer than 1,000 cases in the United States per ...
Ling Ling Rong +7 more
doaj +1 more source
Plant Direct, Volume 10, Issue 9, September 2026.ABSTRACT Plant vasculature is essential for the transport of water, nutrients, and signaling molecules across organs, while also providing critical mechanical support for growth and development. Disruptions in vascular bundle formation can therefore lead to severe physiological and developmental defects.
Anuradha Dhingra +2 more
wiley +1 more source
Diffusion MRI and α‐Synuclein Seed Amplification Status in Parkinson's Disease
Annals of Neurology, Volume 100, Issue 2, Page 295-304, August 2026.Objective Positive α‐synuclein seed amplification assay (SAA) is a biomarker found in most people with Parkinson's disease (PD). We explored if free‐water (FW) imaging detects microstructural differences in the brains of patients with early PD with SAA+ or SAA– status.
Shannon Y. Chiu +145 more
wiley +1 more source
Earth Surface Processes and Landforms, Volume 51, Issue 8, August 2026.Swath profile along the Sındırgı Segment. Grey curves show minimum, mean and maximum elevations, and the thick grey line shows elevation‐corrected Moho depth. Coloured circles indicate relative rock uplift from river‐profile inversion while the red curve shows cumulative uplift.
Savaş Topal +3 more
wiley +1 more source
Concurrent Hashimoto's Encephalopathy and Papillary Thyroid Carcinoma: A Case Report
Clinical and Experimental Neuroimmunology, Volume 17, Issue 3, August 2026.ABSTRACT Background Hashimoto's encephalopathy (HE) is a rare steroid‐responsive autoimmune syndrome. Although HE is associated with anti‐thyroid antibodies, its concurrence with malignant thyroid tumors has rarely been described and its clinical implications remain poorly understood.
Ryo Hara +12 more
wiley +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.Chronic cerebral hypoperfusion induces endothelial hypoxic stress. During the early adaptive phase, the HCG11/QKI5 axis acts upstream of HIF‐1α/VEGF signaling to promote compensatory angiogenesis. With prolonged hypoperfusion, this regulatory pathway declines, leading to impaired vascular adaptation.
Xueqiao Jiao +9 more
wiley +1 more source
Journal of General Virology, 2016 Real-time quaking-induced conversion (RT-QuIC) is a rapid, specific and highly sensitive prion seeding activity detection assay that uses recombinant prion protein (rPrPSen) to detect subinfectious levels of the abnormal isoforms of the prion protein (PrPSc). Although RT-QuIC has been successfully used to detect PrPSc in various tissues from humans and
Rohana P, Dassanayake +8 more
openaire +2 more sources
Chinese Journal of Contemporary Neurology and NeurosurgeryObjective To explore the diagnostic value of cerebrospinal fluid (CSF) biomarkers, total tau protein (t‑tau), phosphorylated tau protein 181 (p‑tau181) and real‑time quaking‑induced conversion (RT ‑QuIC) in sporadic Creutzfeldt‑Jakob disease (sCJD ...
WANG Xiao‑yan +5 more
doaj +1 more source