Results 71 to 80 of about 2,160 (134)

Aerial and Space‐Borne Seismology on Venus: Viability and Design Implications for Future Missions

Earth and Space Science, Volume 13, Issue 6, June 2026.
Abstract Venus' evolution remains a mystery because of the lack of in situ geophysical data to constrain its interior structure. Recently‐selected planetary missions VERITAS (NASA), DAVINCI+ (NASA), and EnVision (ESA) will investigate the planet's interior, surface, and atmospheric chemistry.
Quentin Brissaud, Chenxi Kong, Marouchka Froment, John Wilding, Anna J. P. Gülcher, Jennifer M. Jackson, Iris van Zelst, Raphaël F. Garci, Celine Marie Solberg, Sven Peter Näsholm   +9 more
wiley   +1 more source

Detection of Chronic Wasting Disease in the Lymph Nodes of Free-Ranging Cervids by Real-Time Quaking-Induced Conversion [PDF]

Journal of Clinical Microbiology, 2014
ABSTRACT Chronic wasting disease (CWD), a transmissible spongiform encephalopathy of deer, elk, and moose, is the only prion disease affecting free-ranging animals. Since the disease was first identified in northern Colorado and southern Wyoming in 1967, new epidemic foci of the disease have been identified in 20 additional states, as well as
Nicholas J, Haley, Scott, Carver, Laura L, Hoon-Hanks, Davin M, Henderson, Kristen A, Davenport, Elizabeth, Bunting, Shawn, Gray, Bruce, Trindle, Judith, Galeota, Ivy, LeVan, Tracy, Dubovos, Paul, Shelton, Edward A, Hoover   +12 more
openaire   +2 more sources

Detection of prions in skin punch biopsies of Creutzfeldt–Jakob disease patients

Annals of Clinical and Translational Neurology, 2020
Prion real‐time quaking‐induced conversion (RT‐QuIC) is an ultrasensitive assay detecting pathological aggregates of misfolded prion protein in biospecimens.
Angela Mammana, Simone Baiardi, Marcello Rossi, Alessia Franceschini, Vincenzo Donadio, Sabina Capellari, Byron Caughey, Piero Parchi   +7 more
doaj   +1 more source

Complex Shear‐Wave Splitting Behavior in the Northern Andes and Possible Implications for Mantle Flow Around the Caldas Tear

Journal of Geophysical Research: Solid Earth, Volume 131, Issue 6, June 2026.
Abstract We investigate shear‐wave splitting of SKS and SKKS phases from teleseismic earthquakes to study the anisotropic structure of the lithosphere and upper mantle beneath the Colombian Andes. This area is shaped by complex interactions between the subducting Nazca and Caribbean plates beneath the South American plate. A recent broadband deployment
Christopher J. W. Carchedi, Lara Wagner, Gaspar Monsalve, David S. Avellaneda‐Jiménez, Steven Golden   +4 more
wiley   +1 more source

α-Synuclein conformers reveal link to clinical heterogeneity of α-synucleinopathies

Translational Neurodegeneration, 2023
α-Synucleinopathies, such as Parkinson’s disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy, are a class of neurodegenerative diseases exhibiting intracellular inclusions of misfolded α-synuclein (αSyn), referred to as Lewy bodies ...
Matthias Schmitz, Niccolò Candelise, Sezgi Canaslan, Hermann C. Altmeppen, Jakob Matschke, Markus Glatzel, Neelam Younas, Saima Zafar, Peter Hermann, Inga Zerr   +9 more
doaj   +1 more source

High Relevance of Fatty Acid Oxidation in a Migrating Mammal, the Nathusius' Pipistrelle (Pipistrellus nathusii)

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Bats can sustain powered flight, but their reliance on fatty acid oxidation may limit long‐distance migration compared to birds. Using untargeted metabolomics, we analyzed blood metabolites of Nathusius' pipistrelle under controlled flight and migratory field conditions to identify fuel use.
Alesia Walker, Thuy Thanh Truong, Martin Klingenspor, Anders Hedenström, Gunars Pētersons, Philippe Schmitt‐Kopplin, Shannon E. Currie, Christian C. Voigt   +7 more
wiley   +1 more source

A new diagnostic test for Creutzfeldt-Jakob disease: Real-time quaking-induced conversion (RT-QuIC)

Canada Communicable Disease Report, 2015
Currently, definitive diagnoses of Creutzfeldt-Jakob disease (CJD) require an examination of the brains of deceased patients. In cooperation with an international consortium, Canada's National Microbiology Laboratory is performing a validation of a new test that can diagnose CJD in living patients.
D, Godal, Slr, Simon, K, Cheng, J D, Knox   +3 more
openaire   +2 more sources

Structural conservation of prion strain specificities in recombinant prion protein fibrils in real-time quaking-induced conversion [PDF]

Prion, 2015
A major unsolved issue of prion biology is the existence of multiple strains with distinct phenotypes and this strain phenomenon is postulated to be associated with the conformational diversity of the abnormal prion protein (PrP(Sc)). Real-time quaking-induced conversion (RT-QUIC) assay that uses Escherichia coli-derived recombinant prion protein (rPrP)
Sano, Kazunori, Atarashi, Ryuichiro, Nishida, Noriyuki   +2 more
openaire   +2 more sources

Rapid end-point quantitation of prion seeding activity with sensitivity comparable to bioassays. [PDF]

PLoS Pathogens, 2010
A major problem for the effective diagnosis and management of prion diseases is the lack of rapid high-throughput assays to measure low levels of prions. Such measurements have typically required prolonged bioassays in animals.
Jason M Wilham, Christina D Orrú, Richard A Bessen, Ryuichiro Atarashi, Kazunori Sano, Brent Race, Kimberly D Meade-White, Lara M Taubner, Andrew Timmes, Byron Caughey   +9 more
doaj   +1 more source

Pore Size and Wettability Control Dissolution Trapping Regimes of CO2 in Nano Porous Media

Geophysical Research Letters, Volume 53, Issue 10, 28 May 2026.
Abstract We simulate supercritical carbon dioxide (scCO2 ${\text{scCO}}_{2}$) dissolution in water in nano/submicron pore‐throats (14.3–21.5 nm) using a multi‐component, multiphase pseudopotential lattice Boltzmann model closed by a Peng–Robinson equation of state.
Jiangjiang Wang, Lei Liu, Herbert E. Huppert, Teng Man, Tilsa Aryeni, Ling Li, Sergio Andres Galindo‐Torres   +6 more
wiley   +1 more source