Results 181 to 190 of about 1,574,412 (235)

Differential Adenosine Signaling and Effects of Acute Caffeine Exposure on Alternative Stress Coping Styles in Zebrafish (Danio rerio). [PDF]

Brain Behav
Klucas SE, Wong RY.
europepmc   +1 more source

Synergistic Effect of Hydrophilic Surface and Nano‐Ag2O in TiO2‐Based Composites Coating on Antibacterial and Osteogenic Properties of Low Modulus Ti‐Mo‐Ag Alloy

Rare Metals, Volume 45, Issue 9, September 2026.
ABSTRACT Ti‐15Mo‐2.5Ag alloy exhibited a low modulus and strong antibacterial ability but poor bioactivity. To resolve this problem, sandblasting and anodization were used to create a hydrophilic and nano‐Ag2O‐containing TiO2 coating. Subsequently, the microstructure and physicochemical properties were investigated by scanning electron microscopy, X ...
Yanchun Xie, Junfan Chen, Ming Zhang, Zixin Lin, Hailong Yu, Anwu Xuan, Yi Lian, Lei Yang, Yong Wang, Yuxin Liu, Erlin Zhang, Bing Bai   +11 more
wiley   +1 more source

Caffeine and Headache: Exploring the Multifaceted Relationship. [PDF]

Brain Behav
Hussein M, Hassan A, Al-Azayem SA, Thuraiaiyah J, Schytz HW, Nasser AMA, Magdy R.   +6 more
europepmc   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, Volume 81, Issue 9, Page 3039-3070, September 2026.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
Franziska Roth‐Walter, Ian M. Adcock, Cristina Benito‐Villalvilla, Rodolfo Bianchini, Leif Bjermer, Gaetano Caramori, Luigi Cari, Kian Fan Chung, Zuzana Diamant, Ibon Eguiluz‐Gracia, Edward F. Knol, Milos Jesenak, Francesca Levi‐Schaffer, Giuseppe Nocentini, Liam O'Mahony, Oscar Palomares, Frank Redegeld, Milena Sokolowska, Betty Van Esch, Marco Zurlo, Cristiana Stellato   +20 more
wiley   +1 more source

The biphasic regulatory effect of adenosine A2B receptor in ischemic brain injury and its therapeutic potential. [PDF]

Purinergic Signal
Rui X, Xi W, Mengzhu L, Peiwei S, Mudong L, Chao Z, Wanyu L, Haijun Z.   +7 more
europepmc   +1 more source

The Airway Transcriptome in Type 2 Cytokine Biomarker‐High and ‐Low Severe Asthma

Allergy, Volume 81, Issue 9, Page 3300-3317, September 2026.
This study distinguishes severe asthma–related airway transcriptomic changes from the effects of high‐dose ICS. Most dysregulated genes in severe asthma show concordance with corticosteroid responses. Corticosteroid‐resistant T2‐high asthma featured T2‐high and epithelial barrier gene upregulation, while T2‐low asthma featured Th1/IL‐17 signatures. ASM,
Jiashu Shen, Rekha Chaudhuri, Stephen Bicknell, Adel H. Mansur, Rahul Shrimanker, Ian D. Pavord, Stephen J. Fowler, Vanessa Brown, Lorcan P. McGarvey, Peter H. Howarth, Sven‐Erik Dahlén, Ian M. Adcock, Nazanin Zounemat‐Kermani, Joseph R. Arron, Liam G. Heaney, David F. Choy, Timothy S. C. Hinks, Emanuele Marchi, Peter Bradding, on behalf of the UK Medical Research Council Refractory Asthma Stratification programme (RASP‐UK)   +19 more
wiley   +1 more source

Energy Homeostasis Disruption in Neurological Disorders: Mitochondrial Dysfunction, High-Energy Phosphate Transfer, and Extracellular ATP-Dependent Purinergic Dysregulation. [PDF]

Int J Mol Sci
Tao H, Fujisawa K.
europepmc   +1 more source

Cannabinoid and adenosine A2A receptor crosstalk regulates postnatal and adult hippocampal neurogenesis

British Journal of Pharmacology, Volume 183, Issue 18, Page 5440-5457, September 2026.
Background and purpose Adult neurogenesis is a tightly regulated process affected by both cannabinoid receptors (CB1 and CB2) and adenosine 2A (A2A) receptors, both of which modulate neural progenitor cell activity. While emerging evidence suggests an interaction between these neuromodulatory systems, the extent and mechanism of their interplay in ...
Rui S. Rodrigues, Adam Armada‐Moreira, Laura Gómez‐Acero, Filipa F. Ribeiro, Francisco M. Mouro, Ana M. Sebastião, Francisco Ciruela, Ester Aso, Sara Xapelli   +8 more
wiley   +1 more source

Pharmacological Influences on the R2 Blink Reflex Response in Healthy Participants: A Systematic Review. [PDF]

Eur J Neurosci
Murphy J, Krecke J, Morgan C, Strutton PH, Bannister K, Hughes SW.   +5 more
europepmc   +1 more source

Peripheral κ opioid receptor in pain and inflammation: From molecular signalling and gene expression to drug discovery

British Journal of Pharmacology, Volume 183, Issue 17, Page 5157-5189, September 2026.
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan, Elena C. A. Becker, Boglarka B. Bata, Christian W. Gruber   +3 more
wiley   +1 more source