Results 11 to 20 of about 270,851 (310)

Angiotensin Type 2 Receptor-Mediated Hypotension in Angiotensin Type-1 Receptor-Blocked Rats [PDF]

Hypertension, 2001
The type-2 (AT 2 ) angiotensin (Ang) II receptor has been characterized as potentially counterregulatory to the actions of Ang II at its type-1 (AT 1 ) receptor. We investigated the effects of Ang II and CGP-42112A (CGP), a selective peptide AT
R M, Carey, N L, Howell, X H, Jin, H M, Siragy   +3 more
openaire   +2 more sources

Angiotensin II Type 2 Receptor Antagonizes Angiotensin II Type 1 Receptor–Mediated Cardiomyocyte Autophagy [PDF]

Hypertension, 2009
Autophagy has emerged as an important process in the pathogenesis of cardiovascular diseases, but the proximal triggers for autophagy are unknown. Angiotensin II plays a central role in the pathogenesis of cardiac hypertrophy and heart failure. In this study, we used angiotensin II type 1 (AT 1 ) and type 2 (AT
Porrello, Enzo R., D'Amore, Angelo, Curl, Claire L., Allen, Andrew M., Harrap, Stephen B., Thomas, Walter G., Delbridge, Lea M. D.   +6 more
openaire   +3 more sources

Angiotensin Type 2 Receptor [PDF]

Hypertension, 2015
See related article, pp 396–402 The biological function of the angiotensin type 2 receptor (AT2R) has been difficult to identify, with its role to a large extent masked by the predominate actions of angiotensin II (AngII) at the AT1R.1 However, it is now recognized that the AT2R opposes the actions of the AT1R in the cardiovascular system.
openaire   +2 more sources

Hypertension in COVID-19, A Risk Factor for Infection or A Late Consequence? [PDF]

Cell Journal, 2022
There are a lot of data about the correlation of SARS-CoV-2 infection and hypertension (HTN), but most of themare in the increased risk of morbidity and mortality in patients with HTN. SARS-CoV-2 can interfere with host cellsthrough the renin-angiotensin
Maryam Barekat, Mohammad Amin Shahrbaf, Kosar Rahi, Massoud Vosough   +3 more
doaj   +1 more source

Angiotensin-(1-7) and angiotensin-(1-9): function in cardiac and vascular remodeling [PDF]

, 2014
The renin angiotensin system (RAS) is integral to cardiovascular physiology, however, dysregulation of this system largely contributes to the pathophysiology of cardiovascular disease (CVD).
Akishita, Barroso, Booz, Bosnyak, Bosnyak, Brosnihan, Bruneval, Bryan, Calo, Campbell, Caroline Fattah, Castro, Chappell, Chappell, Chen, Christopher M. Loughrey, Clare A. McKinney, Clarke, Costa, Crackower, Cushman, De Mello, Dias-Peixoto, Domeier, Dong, Donoghue, Donoghue, Drummer, Faria-Silva, Ferreira, Ferreira, Ferreira, Ferreira, Flores-Munoz, Flores-Munoz, Fomovsky, Fraga-Silva, Fraga-Silva, Freeman, Galis, Gava, Gembardt, Gomes, Graeme Milligan, Grobe, Gusev, Hanke, Hannan, Harmer, Heitsch, Horiguchi, Horiuchi, Hunyady, Inaba, Iwata, Jackman, Jaiswal, Jarajapu, Kaminska, Kassiri, Katada, Kokkonen, Kramkowski, Langeveld, Lautner, Liao, Libby, Liu, Loot, Lovren, Masson, McCollum, Mehta, Mercure, Miura, Mogielnicki, Nakajima, Newby, Ng, Nouet, Ocaranza, Ocaranza, Ocaranza, Patel, Patel, Qi, Ray, Rice, Rodgers, Rodrigues-Machado, Ross, Rowe, Sampaio, Sampaio, Santos, Santos, Schultz Jel, Selvetella, Shah, Sheng-Long, Singh, Sluimer, Stegbauer, Strawn, Stuart A. Nicklin, Tallant, Tesanovic, Tipnis, Turner, Uekama, Varagic, Vickers, Vilas-Boas, Walters, Wang, Weber, West, Wiemer, Yamada, Yang, Zeng, Zhang, Zhao, Zhong   +123 more
core   +1 more source

Angiotensin Type 2 Receptor‐Dependent Vasodilation

ChemInform, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Katsutoshi, Yayama, Hiroshi, Okamoto
openaire   +3 more sources

Temporal profile and mechanisms of the prompt sympathoexcitation following coronary ligation in Wistar rats [PDF]

, 2014
Our aim was to assess the timing and mechanisms of the sympathoexcitation that occurs immediately after coronary ligation. We recorded thoracic sympathetic (tSNA) and phrenic activities, heart rate (HR) and perfusion pressure in Wistar rats subjected to ...
Abdala, Ana Paula, Mill, José Geraldo, Moraes, Davi José de Almeida, Passamani, Luciana Mesquita, Paton, Julian Francis Richmond, Sampaio, Karla Nívea   +5 more
core   +14 more sources

Double Deletion of Angiotensin II Type 2 and Mas Receptors Accelerates Aging‐Related Muscle Weakness in Male Mice

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background The activation of AT2 (angiotensin II type 2 receptor ) and Mas receptor by angiotensin II and angiotensin‐(1‐7), respectively, is the primary process that counteracts activation of the canonical renin‐angiotensin system (RAS).
Hikari Takeshita, Koichi Yamamoto, Masaki Mogi, Yu Wang, Yoichi Nozato, Taku Fujimoto, Serina Yokoyama, Kazuhiro Hongyo, Futoshi Nakagami, Hiroshi Akasaka, Yoichi Takami, Yasushi Takeya, Ken Sugimoto, Masatsugu Horiuchi, Hiromi Rakugi   +14 more
doaj   +1 more source

Angiotensin II type 1 and type 2 receptor expression in circulating monocytes of diabetic and hypercholesterolemic patients over 3-month rosuvastatin treatment

Cardiovascular Diabetology, 2012
Background In diabetes, a variety of pro-inflammatory cellular changes has been found in various cell types, including monocytes which are known to be involved in all the phases of atherogenesis.
Marino Franca, Maresca Andrea Maria, Cosentino Marco, Castiglioni Luana, Rasini Emanuela, Mongiardi Christian, Maio Ramona C, Legnaro Massimiliano, Schembri Laura, Dentali Francesco, Grandi Anna Maria, Guasti Luigina   +11 more
doaj   +1 more source

Facilitation of TRKB Activation by the Angiotensin II Receptor Type-2 (AT2R) Agonist C21

Pharmaceuticals, 2021
Blockers of angiotensin II type 1 receptor (AT1R) exert antidepressant-like effects by indirectly facilitating the activation of the angiotensin II type 2 receptor (AT2R), which leads to increased surface expression and transactivation of tropomyosin ...
Liina Laukkanen, Cassiano R. A. F. Diniz, Sebastien Foulquier, Jos Prickaerts, Eero Castrén, Plinio C. Casarotto   +5 more
doaj   +1 more source