Results 91 to 100 of about 5,798 (220)

Neural stem cells express melatonin receptors and neurotrophic factors: colocalization of the MTreceptor with neuronal and glial markers [PDF]

open access: yes, 2004
Background In order to optimize the potential benefits of neural stem cell (NSC) transplantation for the treatment of neurodegenerative disorders, it is necessary to understand their biological characteristics.
McMillan Catherine R   +7 more
core   +1 more source

Behavioral Phenotype and Neuropsychological Profile of an Adult With Smith‐Magenis Syndrome due to a Previously Unreported RAI1 Mutation: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Smith‐Magenis Syndrome (SMS) is an uncommon genetic disorder caused by microdeletions of chromosome 17p11.2 including the RAI1 gene, or loss‐of‐function mutations that directly affect RAI1. Due to the involvement of RAI1 in neurodevelopment, SMS leads to typical pathologic features in the behavioral and physical phenotype that must be ...
Edgar Andrés Chavarría‐Martínez   +4 more
wiley   +1 more source

Anti-oxidants in Parkinson's disease therapy: a critical point of view [PDF]

open access: yes, 2016
Parkinson's disease (PD) is a degenerative neurological syndrome, which is characterized by the preferential death of dopaminergic (DAergic) neurons in the SubstantiaNigra.
Beltramini, Mariano   +3 more
core   +2 more sources

Correlation between sleep problems and morning serum melatonin and ferritin levels in Japanese 5‐year‐old children with autism spectrum disorder

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 5, Issue 1, March 2026.
Abstract Aim Children with autism spectrum disorder (ASD) are more likely to have sleep problems. Few studies have investigated the relationship between sleep problems and blood melatonin and ferritin levels. The objective of this study was to determine the correlation between sleep problems and morning serum melatonin and ferritin levels, and the ...
Ai Terui   +7 more
wiley   +1 more source

Ultrastructural evidence of a secretory role for melatonin in the human parotid gland [PDF]

open access: yes, 2015
In vivo animal studies show that pentagastrin, cholecystokinin and melatonin cause the secretion and synthesis of salivary proteins. Melatonin occurs in large amounts in the gut and is released into the blood on food intake.
Ekstrom, J.   +6 more
core  

Switching from serotonin reuptake inhibitors to agomelatine in patients with refractory obsessive-compulsive disorder: a 3 month follow-up case series [PDF]

open access: yes, 2011
Serotonin reuptake inhibitors (SRIs) currently represent the cornerstone of obsessive-compulsive disorder (OCD) pharmacotherapy. However, OCD is characterized by high rates of partial and/or absent response to standard, recommended treatments, often ...
Michele Fornaro
core   +2 more sources

Sleep quality and sleepiness in adults with multiple myeloma. Is melatonin a potential treatment?

open access: yesPhysiological Reports, Volume 14, Issue 5, March 2026.
Abstract Sleep disturbances significantly impact quality of life in cancer patients, yet remain poorly characterized in multiple myeloma (MM). This observational study aimed to characterize sleep profiles in MM patients and evaluate the therapeutic potential of exogenous melatonin.
Mariana Fiori   +5 more
wiley   +1 more source

Circadian, Sleep and Caloric Intake Phenotyping in Type 2 Diabetes Patients With Rare Melatonin Receptor 2 Mutations and Controls: A Pilot Study

open access: yesFrontiers in Physiology, 2020
BackgroundMelatonin modulates circadian rhythms in physiology and sleep initiation. Genetic variants of the MTNR1B locus, encoding the melatonin MT2 receptor, have been associated with increased type 2 diabetes (T2D) risk. Carriers of the common intronic
Akram Imam   +17 more
doaj   +1 more source

Molecular mechanisms of the sleep wake cycle : therapeutic applications to insomnia [PDF]

open access: yes, 2017
The aim of this review is to explore the molecular mechanism and genetic components of the sleepwake cycle and insomnia. Moreover, we wanted to review the correlation between primary insomnia and its comorbidities.
Grima, Melanie   +2 more
core   +1 more source

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