Results 121 to 130 of about 11,078 (168)

Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells. [PDF]

J Exp Clin Cancer Res
Sabol HM, Paxton BC, Anloague A, Kaur J, Nester MR, Khan S, Smith J, Croucher PI, McDonald MM, Montgomery CO, Stambough JB, Barnes CL, Ambrogini E, Ebetino FH, Schinke C, Ashby C, Delgado-Calle J.   +16 more
europepmc   +1 more source

Bladder Cancer: Uncovering the Predictive Role of NOTCH as an Emerging Candidate Biomarker for Therapeutic Strategies. [PDF]

Cancers (Basel)
Cusumano C, Squillante F, Roma M, Miano R, Felli MP.   +4 more
europepmc   +1 more source

In Vitro Single-Cell Transcriptomic Profiling of Cultured Stem Cells From Apical Papilla and Dental Pulp Stem Cells: Unveiling Cellular Heterogeneity. [PDF]

Int Dent J
Shah MS, Sayegh MA, Khalil MM, Sundarabupathi M, AlKhnbashi O, Samaranayake L, Khyriem C, Sultana M, Egusa H, Jamal M.   +9 more
europepmc   +1 more source

Genotype-phenotype correlations in a Scottish CADASIL cohort and comparison with sporadic small vessel disease. [PDF]

Eur Stroke J
Neilson SJ, Boadu W, Sitaram A, Davidson R, Moreton F, Dickie DA, Dawson J, Muir KW.   +7 more
europepmc   +1 more source

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Overexpression of the Notch3 receptor in non-functioning pituitary tumours

Journal of Clinical Neuroscience, 2012
Human non-functioning pituitary adenomas cause hypopituitarism or the compression of adjacent structures. At present, there is no available medical treatment for these tumours. The Notch3 pathway has an important role in the progression of non-functioning pituitary adenomas.
Zengli, Miao, Yifeng, Miao, Yuchang, Lin, Xiaojie, Lu   +3 more
openaire   +2 more sources

Functional Diversity among Notch1, Notch2, and Notch3 Receptors

Biochemical and Biophysical Research Communications, 2002
To clarify functional diversities among the Notch receptors, we generated truncated forms of Notch1, Notch2, and Notch3 comprising the intracellular domain (aN1, aN2, and aN3) and investigated their transcriptional activities for HES1 and HES5 promoters driving the luciferase reporter gene (HES1-Luc and HES5-Luc).
Kiyoshi, Shimizu, Shigeru, Chiba, Toshiki, Saito, Keiki, Kumano, Yoshio, Hamada, Hisamaru, Hirai   +5 more
openaire   +2 more sources

Physical Interaction of Delta1, Jagged1, and Jagged2 with Notch1 and Notch3 Receptors

Biochemical and Biophysical Research Communications, 2000
The Delta/Serrate/LAG-2 (DSL) domain-containing proteins, Delta1, Jagged1, and Jagged2, are considered to be ligands for Notch receptors. However, the physical interaction between the three DSL proteins and respective Notch receptors remained largely unknown.
K, Shimizu, S, Chiba, T, Saito, K, Kumano, H, Hirai   +4 more
openaire   +2 more sources