Results 91 to 100 of about 22,923 (160)
A Spaetzle-like role for nerve growth factor beta in vertebrate immunity to Staphylococcus aureus [PDF]
, 2014 Many key components of innate immunity to infection are shared between Drosophila and humans. However, the fly Toll ligand Spaetzle is not thought to have a vertebrate equivalent.
A. Kaser +75 more
core +1 more source
Опухоли головы и шеи, 2017 Objective. To study the change of expression of TrkA, p75 receptors and their ratio on the human anaplastic astrocytoma, glioblastoma and medulloblastoma cells cultures exposed to nerve growth factor (NGF) and its combination with cisplatin or ...
A. N. Chernov
doaj +1 more source
Steroid Receptors and Vertebrate Evolution [PDF]
arXiv, 2019 Considering that life on earth evolved about 3.7 billion years ago, vertebrates are young, appearing in the fossil record during the Cambrian explosion about 542 to 515 million years ago. Results from sequence analyses of genomes from bacteria, yeast, plants, invertebrates and vertebrates indicate that receptors for adrenal steroids (aldosterone ...
arxiv
The oncogenic neurotrophin receptor tropomyosin-related kinase variant, TrkAIII
Journal of Experimental & Clinical Cancer Research, 2018 Oncogenes derived from the neurotrophin receptor tropomyosin-related kinase TrkA act as drivers in sub-populations of a wide-range of human cancers. This, combined with a recent report that both adult and childhood cancers driven by novel oncogenic TrkA ...
Antonietta Rosella Farina +6 more
doaj +1 more source
Accuracy of direct gradient sensing by cell-surface receptors [PDF]
arXiv, 2009 Chemotactic cells of eukaryotic organisms are able to accurately sense shallow chemical concentration gradients using cell-surface receptors. This sensing ability is remarkable as cells must be able to spatially resolve small fractional differences in the numbers of particles randomly arriving at cell-surface receptors by diffusion.
arxiv
Molecular Metabolism, 2022 Objective: Brown adipogenesis and thermogenesis in brown and beige adipose tissue (AT) involve vascular remodeling and sympathetic neuronal guidance. Here, we investigated the molecular mechanism coordinating these processes.
Alexes C. Daquinag +3 more
doaj
Chemical sensing by cell-surface chemoreceptor arrays: the roles of receptor cooperativity and adaptation [PDF]
arXiv, 2012 Most sensory cells use cross-membrane chemoreceptors to detect chemical signals in the environment. The biochemical properties and spatial organization of chemoreceptors play important roles in achieving and maintaining sensitivity and accuracy of chemical sensing.
arxiv
Antidepressant-like Effects of Neuropeptide SF (NPSF) [PDF]
World Journal of Research and Review (WJRR) ISSN:2455-3956,
Volume-4, Issue-5, May 2017 Pages 26-30, 2020 Neuropeptide SF (NPSF) is a member of RFamide neuropeptides that play diverse roles in central nervous system. Little is know about the effects of NPSF on brain functions. Antidepressant-like effect of NPSF was studied in modified mice FST. NPSF showed the antidepressant-like effects by decreasing the immobility time and increasing the climbing and ...
arxiv
Journal of Pharmacological Sciences, 2010 Novel agents that inhibit nerve growth factor signaling are required for the treatment of inflammatory pain. The present study investigated the effect of local administration of inhibitory peptide of TrkA (IPTRK3), a synthetic cell-penetrating peptide ...
Koyo Ueda +6 more
doaj
Expression of NGF, Trka and p75 in human cartilage
European Journal of Histochemistry, 2009 Nerve growth factor (NGF) exerts its action through two types of receptor: high-affinity tyrosine kinase A receptor (trkA) and low-affinity p75 receptor.
A Gigante +5 more
doaj +1 more source